Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Death, Sudden D003645 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Eye Burns D005126 13 associated lipids
Acidosis D000138 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Polycythemia Vera D011087 13 associated lipids
Uveitis D014605 14 associated lipids
Angina, Unstable D000789 14 associated lipids
Thrombocytopenia D013921 15 associated lipids
Neutropenia D009503 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Carotid Stenosis D016893 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Celiac Disease D002446 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Choline Deficiency D002796 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Ulcer D014456 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Albuminuria D000419 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Cough D003371 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Chiba Y et al. Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. 1998 Ann. Thorac. Surg. pmid:9456104
Erez E et al. Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin? 1998 Ann. Thorac. Surg. pmid:9456103
Yanagisawa H et al. Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. 1997 Kidney Blood Press. Res. pmid:9453451
Parra T et al. Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. 1998 J. Lab. Clin. Med. pmid:9452128
Moore RM et al. Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. 1998 Jan-Feb Vet Surg pmid:9449176
Dent G et al. Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9448055
Snapper JR et al. Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. 1998 Am. J. Respir. Crit. Care Med. pmid:9445282
Kurosawa M et al. Heterogeneity of mast cells in mastocytosis and inhibitory effect of ketotifen and ranitidine on indolent systemic mastocytosis. 1997 J. Allergy Clin. Immunol. pmid:9440541
Sorem KA and Siler-Khodr TM Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation. 1997 Nov-Dec J Matern Fetal Med pmid:9438218
Sheu JR et al. Triflavin inhibits platelet-induced vasoconstriction in de-endothelialized aorta. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9437193
Qureshi MA and Gore AB Vitamin E exposure modulates prostaglandin and thromboxane production by avian cells of the mononuclear phagocytic system. 1997 Immunopharmacol Immunotoxicol pmid:9436047
Akarsu ES et al. Effect of ciliary neurotrophic factor on body temperature and cerebrospinal fluid prostanoids in the cat. 1998 Brain Res. Bull. pmid:9434196
Famaey JP In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. 1997 Inflamm. Res. pmid:9427063
Gresele P et al. Platelet activation markers in patients with peripheral arterial disease--a prospective comparison of different platelet function tests. 1997 Thromb. Haemost. pmid:9423790
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Oosaki R et al. Urinary excretion of leukotriene E4 and 11-dehydrothromboxane B2 in patients with spontaneous asthma attacks. 1997 Int. Arch. Allergy Immunol. pmid:9414142
Alanko J et al. Catechol estrogens as inhibitors of leukotriene synthesis. 1998 Biochem. Pharmacol. pmid:9413936
Davì G et al. Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group. 1997 Am. J. Respir. Crit. Care Med. pmid:9412557
Gerdemann R et al. [Effect of flunixin meglumine on plasma prostanoid concentrations in horses with colic in the perioperative period]. 1997 DTW. Dtsch. Tierarztl. Wochenschr. pmid:9410724
Davi G et al. In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409316