Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Packham MA et al. | Duration of the effect of aspirin on the synthesis of thromboxane by density subpopulations of rabbit platelets stimulated with thrombin. | 1985 | Blood | pmid:3926022 |
Cattaneo M et al. | Human platelet aggregation and release reaction induced by platelet activating factor (PAF-acether)--effects of acetylsalicylic acid and external ionized calcium. | 1985 | Thromb. Haemost. | pmid:3927505 |
Mobley A and Tai HH | Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3927908 |
Jakubowski JA et al. | Cumulative antiplatelet effect of low-dose enteric coated aspirin. | 1985 | Br. J. Haematol. | pmid:3927970 |
Mehta J et al. | Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides. | 1985 | J. Lab. Clin. Med. | pmid:3928780 |
Callahan KS et al. | Enhancement of the antiaggregatory activity of prostacyclin by propranolol in human platelets. | 1985 | Circulation | pmid:2986877 |
Sawada M et al. | Enzyme-immunoassay of thromboxane B2 at the picogram level. | 1985 | Prostaglandins | pmid:3929333 |
Apprill P et al. | Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors. | 1985 | Circulation | pmid:2988822 |
Fukuda Y | [Plasma prostaglandin and thromboxane levels in asthmatic children]. | 1985 | Arerugi | pmid:2992423 |
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Mehta P et al. | Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. | 1985 | Am J Pediatr Hematol Oncol | pmid:2994511 |
Wilson TW and Tan LK | Low plasma renin activity in diabetes. Relation to urine prostaglandin excretion. | 1985 | Diabetes | pmid:3881302 |
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Mitchell JA et al. | Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets. | 1985 | Prostaglandins Leukot Med | pmid:3883366 |
Wang JP et al. | Antiplatelet effect of hsien-ho-t'sao (Agrimonia pilosa). | 1985 | Am. J. Chin. Med. | pmid:3927704 |
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Paajanen H and Kormano M | Prostacyclin (PGI2) and thromboxane (TXA2) levels during intravenous contrast medium administration in CT. | 1985 | Eur J Radiol | pmid:3896802 |
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Prosdocimi M et al. | Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. | 1985 | Am. J. Physiol. | pmid:3838623 |
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Rinaldo JE and Dauber JH | Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. | 1985 | Circ. Shock | pmid:4053294 |
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Shohami E and Gross J | An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. | 1985 | J. Neurochem. | pmid:3923156 |
Tobian L et al. | Prostaglandin alterations in barely hypertensive Dahl S rats. | 1985 | Trans. Assoc. Am. Physicians | pmid:3842205 |
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