Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gremmel T et al. | Differential impact of inflammation on six laboratory assays measuring residual arachidonic acid-inducible platelet reactivity during dual antiplatelet therapy. | 2013 | J. Atheroscler. Thromb. | pmid:23739624 |
Nakamura A et al. | Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension. | 2013 | Circ. J. | pmid:23676973 |
Bai L et al. | [Effects of electro-acupuncture at Zusanli point on gastric and intestinal blood flow in rats with acute necrotizing pancreatitis]. | 2013 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:24490517 |
Aukema HM et al. | Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome. | 2013 | Br. J. Nutr. | pmid:23151363 |
Kong X et al. | High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats. | 2013 | J. Vasc. Surg. | pmid:23069071 |
Kovarik JJ et al. | Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes. | 2013 | Immunology | pmid:23398566 |
Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |
Chen CY et al. | Functional analysis of human thromboxane synthase polymorphic variants. | 2012 | Pharmacogenet. Genomics | pmid:22735388 |
Wen SH et al. | Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation. | 2012 | Shock | pmid:22777122 |
Pelligand L et al. | Pharmacokinetic/pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation. | 2012 | J. Vet. Pharmacol. Ther. | pmid:21767277 |
Wenzel F et al. | Determination of thromboxane formation, soluble CD40L release and thrombopoietin clearance in apheresis platelet concentrates. | 2012 | Platelets | pmid:21806498 |
Cesari M et al. | Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. | 2012 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:22389462 |
Dragani A et al. | Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism. | 2012 | Thromb. Haemost. | pmid:22782530 |
Saito Y et al. | Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22427514 |
Skarke C et al. | Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. | 2012 | Clin. Pharmacol. Ther. | pmid:22278334 |
Chen C et al. | [Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22979933 |
Etulain J et al. | Acidosis downregulates platelet haemostatic functions and promotes neutrophil proinflammatory responses mediated by platelets. | 2012 | Thromb. Haemost. | pmid:22159527 |
Ju HK et al. | Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rkâ‚ reveals attenuated 12-HETE production. | 2012 | J. Proteome Res. | pmid:22873173 |
Matsuura E et al. | On aspirin treatment but not baseline thromboxane B2 levels predict adverse outcomes in patients with acute coronary syndromes. | 2012 | J. Thromb. Haemost. | pmid:22784188 |
Chandrasekaran CV et al. | In vitro comparative evaluation of non-leaves and leaves extracts of Andrographis paniculata on modulation of inflammatory mediators. | 2012 | Antiinflamm Antiallergy Agents Med Chem | pmid:22882083 |