Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mitchell MD et al. Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. 1979 J. Reprod. Fertil. pmid:423152
Tremoli E et al. Platelet thromboxanes and serum-cholesterol. 1979 Lancet pmid:84115
Makheia AN et al. Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. 1979 Lancet pmid:86023
Lewy RI et al. Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. 1979 Lancet pmid:87990
Güllner HG et al. Prostacyclin overproduction in Bartter's syndrome. 1979 Lancet pmid:90861
Davis TM et al. Prostacyclin and thromboxane metabolites in diabetes. 1979 Lancet pmid:90875
Best LC et al. Mode of action of dipyridamole on human platelets. 1979 Thromb. Res. pmid:229583
Marcus AJ The role of prostaglandins in platelet function. 1979 Prog Hematol pmid:230534
Spagnuolo C et al. PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. 1979 Prostaglandins pmid:230539
Jonsson CE et al. Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury. 1979 Acta Physiol. Scand. pmid:232367
Karmazyn M and Dhalla NS Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. 1979 Prostaglandins Med pmid:233217
Boura AL and Murphy RD Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. 1978 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:699382
Davies GC et al. Thromboxane B2 and fibrinopeptide A levels in platelet consumption and thrombosis. 1978 Surg Forum pmid:401227
Mitchell MD et al. Possible role for prostacyclin in human parturition. 1978 Prostaglandins pmid:373020
Morita I et al. Characterization of thromboxane B2 and 6-ketoprostaglandin F alpha by combined gas chromatography and chemical-ionization mass spectrometry. 1978 J. Chromatogr. pmid:681479
Mitchell MD et al. Production of thromboxane B2 by intra-uterine tissues from pregnant goats in vitro. 1978 J. Endocrinol. pmid:681871
Fitzpatrick FA et al. An antiserum against 9,11-azo-15-hydroxyprosta-5,13-dienoic acid recognises and binds prostaglandin endoperoxides. 1978 Nature pmid:652034
Cerskus AL et al. Effects of indomethacin and sulfinpyrazone on in vivo formation of thromboxane B2 and prostaglandin D2 during arachidonate infusion in rabbits. 1978 Thromb. Res. pmid:653641
Mitchell MD et al. Thromboxane B2 in amniotic fluid before and during labour. 1978 Br J Obstet Gynaecol pmid:656348
Raz A et al. Biosynthesis of thromboxane B2 and 12-L-hydroxy-5,8,10-heptadecatrienoic acid in human platelets. Evidence for a common enzymatic pathway. 1978 Eur. J. Biochem. pmid:658053
Salmon JA A radioimmunoassay for 6-keto-prostaglandin F1alpha. 1978 Prostaglandins pmid:663275
Davidson EM et al. The release of thromboxane B2 by rabbit peritoneal polymorphonuclear leucocytes [proceedings]. 1978 Br. J. Pharmacol. pmid:667479
Goldstein IM et al. Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. 1978 J. Exp. Med. pmid:702055
Anhut H et al. Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. 1978 Prostaglandins pmid:704912
Nelson NA et al. Synthesis of thromboxane B2 metabolites. 1978 Prostaglandins pmid:704927
Marion J and Wolfe LS Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. 1978 Prostaglandins pmid:704928
Kitchen EA et al. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. 1978 Prostaglandins pmid:704931
Sors H et al. Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. 1978 Prostaglandins pmid:704933
Turk J et al. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. 1978 Prostaglandins pmid:704934
Raz A and Aharony D Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. 1978 Res. Commun. Chem. Pathol. Pharmacol. pmid:705027
Chang WC et al. Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. 1978 Biochem. Pharmacol. pmid:619892
Goetzl EJ and Gorman RR Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). 1978 J. Immunol. pmid:621391
Yoshimoto T et al. Selective inhibition of prostaglandin endoperoxide thromboxane isomerase by 1-carboxyalkylimidazoles. 1978 Prostaglandins pmid:725083
Anderson MW et al. Kinetic studies on the conversion of prostaglandin endoperoxide PGH2 by thromboxane synthase. 1978 Prostaglandins pmid:725086
Mitchell MD et al. Concentrations of thromboxane B2 in the maternal and foetal plasma of sheep during late pregnancy and induced parturition [proceedings]. 1978 J. Endocrinol. pmid:731165
Anhut H et al. Release of 15-keto-13, 14-dihydro-thromboxane B2 and prostaglandin D2 during anaphylaxis as measured by radioimmunoassay. 1978 Naunyn Schmiedebergs Arch. Pharmacol. pmid:740052
McMillan RM et al. Malonaldehyde formation in intact platelets is catalysed by thromboxane synthase. 1978 Biochem. J. pmid:743261
Chignard M et al. Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs. 1978 Biochem. Biophys. Res. Commun. pmid:743319
Mitchell MD and Robinson JS Concentrations of 6-oxo-prostaglandin F1 alpha and thromboxane B2 in the tracheal fluid of foetal sheep. 1978 J. Endocrinol. pmid:744937
Agradi E et al. Influence of short term dietary supplementation of different lipids on aggregation and arachidonic acid metabolism in rabbit platelets. 1978 Prostaglandins pmid:748984
Fitzpatrick FA and Gorman RR A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. 1978 Biochim. Biophys. Acta pmid:629996
Malik KU Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. 1978 Circ. Res. pmid:27321
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
Roberts LJ et al. Metabolism of thromboxane B2 in the monkey. 1978 J. Biol. Chem. pmid:97291
Mitchell MD et al. Production of thromboxane B2 by the intra-uterine tissues from late pregnant Rhesus monkeys (Macaca mulatta) in vitro. 1978 J. Endocrinol. pmid:101641
Barac G [Does thromboxane B2 influence renal blood flow? (proceedings)]. 1978 Arch. Int. Physiol. Biochim. pmid:80176
Engineer DM et al. Modulation of slow-reacting substance of anaphylaxis and histamine release by prostacyclin and thromboxanes [proceedings]. 1978 J. Physiol. (Lond.) pmid:81301
Best LC et al. Dipyridamole and platelet function. 1978 Lancet pmid:81402
Adcock JJ et al. The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. 1978 Prostaglandins pmid:81495
Hyman AL et al. Prostaglandins and the lung. 1978 Am. Rev. Respir. Dis. pmid:339796