Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Bisordi JE et al. Interaction of vasopressin and prostaglandins in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777397
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
Galli C et al. Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. 1980 Prog Food Nutr Sci pmid:6779348
Best LC et al. Studies on the role of calcium in the control of thromboxane B2 production. 1980 Artery pmid:6783015
Crutchley DJ et al. Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. 1980 Am. Rev. Respir. Dis. pmid:6155814
Patrono C et al. Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. 1980 Agents Actions Suppl. pmid:6787852
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Silver MJ et al. A model system for studying initial events in atherosclerosis. 1980 Artery pmid:7000044
Best LC et al. Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. 1980 Biochim. Biophys. Acta pmid:6251913
Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
Poyser NL and Scott FM Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. 1980 J. Reprod. Fertil. pmid:7001011
Lands WE et al. Recent concepts on platelet function and dietary lipids in coronary thrombosis, vasospasm and angina. 1980 Herz pmid:7007191
Subbiah MT et al. Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. 1980 Pharmacology pmid:7220591
Ali AE et al. Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. 1980 Prostaglandins pmid:7008090
Ohtsu E and Matsuzawa T Metabolic alterations in the endogenous formation of 6 keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in the brain-stem of stroke-resistant spontaneously hypertensive rats. 1980 J. Nutr. Sci. Vitaminol. pmid:7229740
Vargaftig BB et al. Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. 1980 Eur. J. Pharmacol. pmid:7009169
Giri SN and Krishna GA Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. 1980 J Pharmacol Methods pmid:7009992
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Jécsai G and Bagdány S Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. 1980 Acta Biochim. Biophys. Acad. Sci. Hung. pmid:7282294
Hwang DH Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. 1980 Prostaglandins Med pmid:7413850
Cerskus AL et al. Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone. 1980 Thromb. Res. pmid:7414555
Tada M et al. Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease. 1980 Adv Myocardiol pmid:7423053
Matsumoto M et al. Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. 1980 Thromb. Haemost. pmid:7423441
Davies GC et al. Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass. 1980 Circulation pmid:6965618
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Galli C et al. Modulation of prostaglandin production in tissues by dietary essential fatty acids. 1980 Acta Med. Scand. Suppl. pmid:6935943
Wong PY et al. The role of calmodulin in prostaglandin metabolism. 1980 Ann. N. Y. Acad. Sci. pmid:6940495
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Cooper JD et al. Prostaglandin production associated with the pulmonary vascular response to complement activation. 1980 Surgery pmid:7394704
Dupont J et al. Effects of dietary essential fatty acid concentration upon prostanoid synthesis in rats. 1980 J. Nutr. pmid:7400858
Rao GH et al. Influence of epinephrine on the aggregation response of aspirin-treated platelets. 1980 Prostaglandins Med pmid:7403340
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Hassid A and Dunn MJ Microsomal prostaglandin biosynthesis of human kidney. 1980 J. Biol. Chem. pmid:7358683
Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Van Praag D and Farber SJ Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. 1980 Adv Prostaglandin Thromboxane Res pmid:7369029
Lindgren JA et al. Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6247886
Kot PA et al. Modification of the cardiovascular actions of prostaglandins by thromboxane B2. 1980 Adv Prostaglandin Thromboxane Res pmid:7369035
Gorman RR Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. 1980 Adv Prostaglandin Thromboxane Res pmid:6247892
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lewy RI Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. 1980 Haemostasis pmid:7372200
Wise WC et al. Ibuprofen improves survival from endotoxic shock in the rat. 1980 J. Pharmacol. Exp. Ther. pmid:7452480
Subbiah MT et al. Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. 1980 Thromb. Haemost. pmid:7455983
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751
Lewy RI et al. Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. 1980 Circulation pmid:7371128
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618