Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Angina Pectoris, Variant D000788 3 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Gross GJ and Moore J Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. 2004 Pharmacology pmid:15161995
Suzuki N et al. Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. 2004 Prostaglandins Other Lipid Mediat. pmid:15165035
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Craft JA et al. Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. 2004 Blood Coagul. Fibrinolysis pmid:15311156
Ferroni P et al. Platelet activation in type 2 diabetes mellitus. 2004 J. Thromb. Haemost. pmid:15304032
Di Nunno L et al. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. 2004 J. Med. Chem. pmid:15369392
Mak IT et al. Cardiac pathologic effects of azidothymidine (AZT) in Mg-deficient mice. 2004 Cardiovasc. Toxicol. pmid:15371632
Valeri CR et al. In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. 2004 J Trauma pmid:15280746
Singer P and Wirth M Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15253884
Bruno A et al. Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. 2004 Stroke pmid:14963281
Kwak SH et al. Effects of propofol on endotoxin-induced acute lung injury in rabbit. 2004 J. Korean Med. Sci. pmid:14966342
Scott G et al. Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. 2004 J Clin Pharmacol pmid:14747429
Arrebola MM et al. In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. 2004 J. Cardiovasc. Pharmacol. pmid:14668571
Freitas CF et al. Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. 2004 J. Cardiovasc. Pharmacol. pmid:14668575
Cotter G et al. Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? 2004 Am. Heart J. pmid:14760328
Fan JG et al. [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. 2004 Zhonghua Gan Zang Bing Za Zhi pmid:15623379
Vega-Ostertag M et al. Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. 2004 Arthritis Rheum. pmid:15457460
Noverr MC and Huffnagle GB Regulation of Candida albicans morphogenesis by fatty acid metabolites. 2004 Infect. Immun. pmid:15501745
Rocca B et al. Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. 2004 Exp. Hematol. pmid:15504548
Chou DS et al. Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. 2004 Lipids pmid:15506238
He W et al. Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis. 2004 J Tradit Chin Med pmid:15510809
Chiang N et al. Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15471991
Kawata K et al. The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. 2003 Nov-Dec Hepatogastroenterology pmid:14696445
Lang I et al. Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. 2003 Eur. J. Cell Biol. pmid:12751902
Molina V et al. Synergistic effect of D-003 and aspirin on experimental thrombosis models. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711246
Chavarría ME et al. Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. 2003 Am. J. Obstet. Gynecol. pmid:12712098
Dogné JM et al. Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538090
De La Cruz P et al. Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. 2003 Naunyn Schmiedebergs Arch. Pharmacol. pmid:12595963
Uchida M et al. Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. 2003 Anesth. Analg. pmid:12598238
Zaitsu M et al. Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. 2003 Am. J. Hematol. pmid:12555215
Sidhu P et al. Tissue chamber model of acute inflammation in farm animal species. 2003 Res. Vet. Sci. pmid:12507568
Wolfram R et al. Daily prickly pear consumption improves platelet function. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12878452
Yu CC and Lai YL Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. 2003 Life Sci. pmid:12927588
Zhuang HP et al. [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. 2003 Hunan Yi Ke Da Xue Xue Bao pmid:12934393
Castellani S et al. Thromboxane inhibition improves renal perfusion and excretory function in severe congestive heart failure. 2003 J. Am. Coll. Cardiol. pmid:12849673
Pettus BJ et al. Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. 2003 J. Biol. Chem. pmid:12855693
Shimada N et al. Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients. 2003 Ren Fail pmid:12911161
Yi H et al. [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. 2003 Zhonghua Gan Zang Bing Za Zhi pmid:14636441
Kankuri E et al. Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. 2003 Thromb. Res. pmid:14592552
Zhang C et al. Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. 2003 J. Hypertens. pmid:14597858
Wang ZF et al. The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. 2003 HBPD INT pmid:14599960
Eder K et al. Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. 2003 J. Nutr. pmid:14652352
Li JS et al. [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. 2003 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:14552688
Gu L et al. [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15224660
Dong WG et al. Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. 2003 World J. Gastroenterol. pmid:14606091
Li D et al. Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. 2003 Biomed. Environ. Sci. pmid:15011964
Huang RJ et al. [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12764908
Li ZG et al. [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12764922
Lei D et al. Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract. 2003 J. Agric. Food Chem. pmid:12643677
Park WH et al. The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity. 2003 Int. Immunopharmacol. pmid:12810354