Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Yang Deficiency D016711 3 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Hu Y et al. Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. 2009 Immunopharmacol Immunotoxicol pmid:19874221
Huntjens DR et al. Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. 2009 Eur J Pain pmid:18774319
Jespersen B et al. Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. 2009 Nephrol. Dial. Transplant. pmid:19193738
Chen SS et al. Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. 2009 Diabet. Med. pmid:19236624
Kanazawa S et al. Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. 2009 Platelets pmid:19172526
Calapai G et al. Cardiovascular biomarkers in groups of established smokers after a decade of smoking. 2009 Basic Clin. Pharmacol. Toxicol. pmid:19175368
Kapetanovic IM et al. Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. 2009 Chem. Biol. Interact. pmid:18992230
Lauring B et al. Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. 2009 J Clin Pharmacol pmid:19833861
Eriksson AC et al. Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. 2009 J Transl Med pmid:19508722
Cattaneo M Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". 2009 Circulation pmid:19546394
Schiff M et al. Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. 2009 Curr Med Res Opin pmid:19678751
Cook VL et al. Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. 2009 Am. J. Vet. Res. pmid:19645580
Blais N et al. Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). 2009 Thromb. Haemost. pmid:19652893
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Larson MK et al. Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. 2008 Thromb. Haemost. pmid:18841286
Kaehler S et al. S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. 2008 Pharmacology pmid:18043009
Graff J et al. Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. 2008 J. Antimicrob. Chemother. pmid:18156609
Delgado-Lista J et al. Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. 2008 Am. J. Clin. Nutr. pmid:18258620
Tanen DA et al. Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. 2008 Ann Pharmacother pmid:18698012
Rao CV et al. Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. 2008 Int. J. Oncol. pmid:18813794