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Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
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Leese PT et al. |
The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. |
2003 |
J Clin Pharmacol |
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Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. |
2003 |
Eur. J. Cell Biol. |
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Molina V et al. |
Synergistic effect of D-003 and aspirin on experimental thrombosis models. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Yregård L et al. |
Influence of local anaesthetics on inflammatory activity postburn. |
2003 |
Burns |
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Comparison of nasal and oral inhalation during exhaled breath condensate collection. |
2003 |
Am. J. Respir. Crit. Care Med. |
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Vani G et al. |
Histone H1 modulates immune status in experimental breast cancer. |
2003 |
Chemotherapy |
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Xia Z et al. |
Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. |
2003 |
J. Thorac. Cardiovasc. Surg. |
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Rossoni G et al. |
Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. |
2003 |
Eur. J. Pharmacol. |
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Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
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Yokoyama Y et al. |
Role of thromboxane in producing portal hypertension following trauma-hemorrhage. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Lombard JH et al. |
High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12456391
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Sheu JR et al. |
Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. |
2003 |
Exp. Biol. Med. (Maywood) |
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Bellou A et al. |
Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. |
2003 |
Shock |
pmid:12558148
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De León EJ et al. |
A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. |
2003 |
J. Pharm. Pharmacol. |
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Dong WG et al. |
Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. |
2003 |
World J. Gastroenterol. |
pmid:14606091
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Fujimoto Y et al. |
Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets. |
2003 |
Toxicol. Appl. Pharmacol. |
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Halushka MK et al. |
Genetic variation in cyclooxygenase 1: effects on response to aspirin. |
2003 |
Clin. Pharmacol. Ther. |
pmid:12545150
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Yokoyama Y et al. |
Role of thromboxane A2 in early BDL-induced portal hypertension. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12431905
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Nagase T et al. |
A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12505870
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Hart RG et al. |
Aspirin dosage and thromboxane synthesis in patients with vascular disease. |
2003 |
Pharmacotherapy |
pmid:12741431
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Pfeiffer S et al. |
Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. |
2003 |
Transplantation |
pmid:12698079
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Arifah AK et al. |
Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. |
2003 |
J. Vet. Pharmacol. Ther. |
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Ji Y et al. |
Thrombosis and its significance after experimental pulmonary thromboembolism. |
2003 |
Chin. Med. J. |
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Davì G et al. |
Platelet activation in obese women: role of inflammation and oxidant stress. |
2002 Oct 23-30 |
JAMA |
pmid:12387653
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Hayashi M et al. |
Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. |
2002 Nov-Dec |
Eur. J. Haematol. |
pmid:12460234
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Wolfram RM et al. |
Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. |
2002 May-Jun |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12144875
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Alarayyed NA et al. |
Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. |
2002 Aug-Sep |
Platelets |
pmid:12189011
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Pinheiro RM and Calixto JB |
Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. |
2002 |
Inflamm. Res. |
pmid:12558194
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Saldeen P et al. |
Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism. |
2002 |
J. Matern. Fetal. Neonatal. Med. |
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The effect of submaximal exercise on platelet aggregation during late follicular and midluteal phases in women. |
2002 |
Thromb. Res. |
pmid:12590951
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Küsters S et al. |
Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. |
2002 |
Arzneimittelforschung |
pmid:11878205
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Schelzig H et al. |
Role of recombinant hirudin in a pig-to-human lung transplantation model. |
2002 |
Transplant. Proc. |
pmid:12270449
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Huang CG et al. |
Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells. |
2002 |
Thromb. Res. |
pmid:12297129
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Lees P and Landoni MF |
Pharmacodynamics and enantioselective pharmacokinetics of racemic carprofen in the horse. |
2002 |
J. Vet. Pharmacol. Ther. |
pmid:12485349
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Lassus P et al. |
Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants. |
2002 |
Early Hum. Dev. |
pmid:11893431
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Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11893597
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[Relationship between cyclooxygenase-2 protein expression, prostaglandins levels and biologic behavior in ovarian carcinoma tissue]. |
2002 |
Zhonghua Fu Chan Ke Za Zhi |
pmid:12487927
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Wainwright CL et al. |
NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs. |
2002 |
Br. J. Pharmacol. |
pmid:11959790
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[Changes of blood vessel active substances in acute pulmonary embolism induced by echinococus granulous cyst in rabbits]. |
2002 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:12490126
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Sheu JR et al. |
Mechanisms involved in the antiplatelet activity of midazolam in human platelets. |
2002 |
Anesthesiology |
pmid:11873041
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Horiguchi T et al. |
Study on the usefulness of seratrodast in the treatment of chronic pulmonary emphysema. |
2002 |
Arzneimittelforschung |
pmid:12442639
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Zaitsu M et al. |
Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468261
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The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468270
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Dai CF et al. |
[Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. |
2002 |
Zhonghua Nan Ke Xue |
pmid:12479132
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Khan I et al. |
Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam. |
2002 |
Scand. J. Gastroenterol. |
pmid:12523593
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Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. |
2002 |
Circulation |
pmid:12451006
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Leahy KM et al. |
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. |
2002 |
Cancer Res. |
pmid:11830509
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Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. |
2002 |
Prostaglandins Other Lipid Mediat. |
pmid:12428679
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Ma LP et al. |
Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. |
2002 |
J Assoc Acad Minor Phys |
pmid:11852667
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Ochi T and Goto T |
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. |
2002 |
Br. J. Pharmacol. |
pmid:11834626
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De La Cruz JP et al. |
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction. |
2002 |
Br. J. Pharmacol. |
pmid:12429581
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Bruno A et al. |
Aspirin and urinary 11-dehydrothromboxane B(2) in African American stroke patients. |
2002 |
Stroke |
pmid:11779889
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Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. |
2002 |
J. Cardiovasc. Pharmacol. |
pmid:11791012
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Bayorh MA et al. |
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats. |
2002 |
Peptides |
pmid:11814618
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Jeng JH et al. |
Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. |
2002 |
Free Radic. Biol. Med. |
pmid:11978487
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Streppa HK et al. |
Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. |
2002 |
Am. J. Vet. Res. |
pmid:16206787
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Jiang Z et al. |
[The changes of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha(6-keto-PGF1 alpha) in the lungs of rats drowned in hypothermic-sea-water]. |
2002 |
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi |
pmid:14694611
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Saareks V et al. |
Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. |
2002 |
Pharmacol. Toxicol. |
pmid:12403056
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Kudolo GB et al. |
Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. |
2002 |
Thromb. Res. |
pmid:12590952
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Obase Y et al. |
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. |
2002 |
Chest |
pmid:11796443
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Gordon SM et al. |
Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: replicate clinical trials in a tissue injury model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12189364
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Effects of enteric-coated, low-dose aspirin on parameters of platelet function. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:12197849
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Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. |
2002 |
J. Biol. Chem. |
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Khan AA et al. |
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12152003
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Tzanakakis GN et al. |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
pmid:12630766
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Kirchheiner J et al. |
Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12152005
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Wang L et al. |
Enhancement of human platelet activation by the combination of low concentrations of collagen and rabbit anticardiolipin antibodies. |
2002 |
Br. J. Haematol. |
pmid:12199800
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Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors. |
2002 |
Eur J Med Chem |
pmid:12204472
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Cipollone F et al. |
Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. |
2002 |
Circulation |
pmid:12135935
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Association between ibuprofen, aspirin therapy found. |
2002 |
J Am Dent Assoc |
pmid:12136787
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Rinder HM et al. |
Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. |
2002 |
J Clin Pharmacol |
pmid:12162470
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Wong DA et al. |
Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2). |
2002 |
J. Exp. Med. |
pmid:12163563
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Jankov RP et al. |
Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:12119234
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Giardiello FM et al. |
Primary chemoprevention of familial adenomatous polyposis with sulindac. |
2002 |
N. Engl. J. Med. |
pmid:11932472
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Signorello MG et al. |
Effect of homocysteine on arachidonic acid release in human platelets. |
2002 |
Eur. J. Clin. Invest. |
pmid:11952814
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Yamasaki M et al. |
No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. |
2002 |
Eur. J. Pharmacol. |
pmid:11937106
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Eikelboom JW et al. |
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. |
2002 |
Circulation |
pmid:11940542
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Knijff-Dutmer EA et al. |
Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis. |
2002 |
Rheumatology (Oxford) |
pmid:11961179
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Hayashi M et al. |
The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. |
2002 |
Acta Obstet Gynecol Scand |
pmid:11966476
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Leese PT et al. |
Valdecoxib does not impair platelet function. |
2002 |
Am J Emerg Med |
pmid:12098171
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Tsukamoto H et al. |
Simultaneous quantification of prostaglandins, isoprostane and thromboxane in cell-cultured medium using gas chromatography-mass spectrometry. |
2002 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:12076690
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Sakai H et al. |
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon. |
2002 |
Br. J. Pharmacol. |
pmid:12023941
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Jung K et al. |
The effect of dietary intervention through the modification of fatty acids composition and antioxidant vitamin intake on plasma TXB(2) level in Korean postmenopausal women with hypercholesterolemia. |
2002 |
J. Korean Med. Sci. |
pmid:12068132
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Jung YS et al. |
Antithrombotic effect of onion in streptozotocin-induced diabetic rat. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12054917
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van Kraaij DJ et al. |
A comparison of the effects of nabumetone vs meloxicam on serum thromboxane B2 and platelet function in healthy volunteers. |
2002 |
Br J Clin Pharmacol |
pmid:12047490
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Appleyard CB et al. |
Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis. |
2002 |
Dig. Dis. Sci. |
pmid:12353846
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Saldeen P et al. |
Structural, functional and circulatory placental changes associated with impaired glucose metabolism. |
2002 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:12381475
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Zhang H et al. |
[Perioperative lung injury in ventricular septal defect with severe pulmonary hypertension, a clinical study of 31 cases]. |
2002 |
Zhonghua Yi Xue Za Zhi |
pmid:12425808
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Jones CJ et al. |
In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. |
2002 |
Am. J. Vet. Res. |
pmid:12428662
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Buluç M et al. |
Effect of misoprostol and indomethacin on cyclooxygenase induction and eicosanoid production in carrageenan-induced air pouch inflammation in rats. |
2002 |
Prostaglandins Other Lipid Mediat. |
pmid:12428691
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Gray PA et al. |
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. |
2002 |
Br. J. Pharmacol. |
pmid:12429575
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Valeri CR et al. |
Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy. |
2002 |
Transfusion |
pmid:12430680
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Yokoyama C et al. |
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. |
2002 |
Circulation |
pmid:12403673
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Evgenov OV et al. |
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. |
2002 |
Eur. Respir. J. |
pmid:12412689
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Bergh K et al. |
Production of prostaglandin e(2) by iridial melanocytes exposed to latanoprost acid, a prostaglandin F(2 alpha) analogue. |
2002 |
J Ocul Pharmacol Ther |
pmid:12419090
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Chen TL et al. |
[Effects of fast decompression on prostaglandins content in cerebral tissue of guinea pigs]. |
2002 |
Space Med Med Eng (Beijing) |
pmid:12222577
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Kim H et al. |
Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells. |
2002 |
Pharmacology |
pmid:12393940
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Shashikant MP et al. |
Physicochemical properties of perfluorochemical liquids influence ventilatory requirements, pulmonary mechanics, and microvascular permeability during partial liquid ventilation following intestinal ischemia/reperfusion injury. |
2002 |
Crit. Care Med. |
pmid:12394959
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Ferlito M et al. |
Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production. |
2002 |
J. Endotoxin Res. |
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