Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Glomerulonephritis, Membranous D015433 6 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Wounds and Injuries D014947 20 associated lipids
Weil Disease D014895 2 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Hsu MF et al. Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A. 2008 Eur. J. Pharmacol. pmid:18834875
Kaneko I et al. Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. 2008 Biochem. Biophys. Res. Commun. pmid:18190789
Parsons JP et al. Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. 2008 J Asthma pmid:18569228
Natarajan G et al. Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. 2008 Am J Perinatol pmid:18726836
Santilli F et al. Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. 2008 Blood pmid:18541722
Mitsopoulos P et al. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. 2008 Int J Pharm pmid:18694812
Yokoyama Y et al. Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. 2008 Shock pmid:17885643
Meen O et al. No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. 2008 Scand. J. Clin. Lab. Invest. pmid:17934975
Zhao S et al. Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. 2008 Placenta pmid:17936899
Larson MK et al. Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. 2008 Thromb. Haemost. pmid:18841286
Aslam R et al. Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18215184
Toscano CD et al. NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. 2008 Neurotoxicology pmid:18834901
Lee CR et al. Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. 2008 Clin. Pharmacol. Ther. pmid:17495879
Gao L et al. [Effects of supplementing qi and activating blood circulation method on platelet aggregation rate, adhesion rate and thromboxane B2 level in patients with stable angina pectoris and intolerable to aspirin]. 2008 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:18543479
Patrignani P et al. Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. 2008 Pharmacogenet. Genomics pmid:18551041
Cheuk BL and Cheng SW Can local secretion of prostaglandin E2, thromboxane B2, and interleukin-6 play a role in ruptured abdominal aortic aneurysm? 2008 World J Surg pmid:17992560
Francois H et al. A role for the thromboxane receptor in L-NAME hypertension. 2008 Am. J. Physiol. Renal Physiol. pmid:18684890
Guthikonda S et al. Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy. 2008 Thromb. Haemost. pmid:18612542
Kaehler S et al. S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. 2008 Pharmacology pmid:18043009
Elander N et al. Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. 2008 Biochem. Biophys. Res. Commun. pmid:18485889
Abdelwhab S and Elshinnawy S Pulmonary hypertension in chronic renal failure patients. 2008 Am. J. Nephrol. pmid:18635926
Graff J et al. Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. 2008 J. Antimicrob. Chemother. pmid:18156609
Delgado-Lista J et al. Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. 2008 Am. J. Clin. Nutr. pmid:18258620
Tanen DA et al. Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. 2008 Ann Pharmacother pmid:18698012
Nocun M et al. French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. 2008 Biomed. Pharmacother. pmid:17698319
Park MK et al. Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. 2008 Phytother Res pmid:17724769
Rao CV et al. Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. 2008 Int. J. Oncol. pmid:18813794
Rajec J et al. Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk. 2008 Bratisl Lek Listy pmid:18814431
Helgason CM et al. Platelet aggregation and recruitment with aspirin-clopidogrel therapy. 2008 Cerebrovasc. Dis. pmid:18349532
Momen A et al. Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18326807
Skoglund C et al. C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. 2008 Immunol. Cell Biol. pmid:18332893
Menzies D et al. Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. 2008 J. Allergy Clin. Immunol. pmid:18313127
Geske FJ et al. AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. 2008 Mol Diagn Ther pmid:18288882
Hasan J et al. Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. 2008 Prostaglandins Other Lipid Mediat. pmid:18096423
Hinz B et al. Impact of naproxen sodium at over-the-counter doses on cyclooxygenase isoforms in human volunteers. 2008 Int J Clin Pharmacol Ther pmid:18397691
Bruce EC et al. Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. 2008 Psychosom Med pmid:18378867
Wooten JG et al. Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. 2008 Am. J. Vet. Res. pmid:18380576
Eikelboom JW et al. Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. 2008 Circulation pmid:18838564
Banting A et al. Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. 2008 Vet. Rec. pmid:18953074
Ruan KH et al. An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. 2008 FEBS J. pmid:19021758
Jiang H et al. The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases. 2008 J Tradit Chin Med pmid:19004202
Otani Y et al. Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. 2007 May-Jun J Invest Surg pmid:17613692
Jiang J et al. Endothelin-1 blockade prevents COX2 induction and TXA2 production in the fructose hypertensive rat. 2007 Mar-Apr Can. J. Physiol. Pharmacol. pmid:17612651
Csanyi G et al. Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. 2007 Jul-Aug Pharmacol Rep pmid:17901574
Komers R et al. Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. 2007 Jan-Feb Clin. Exp. Pharmacol. Physiol. pmid:17201733
González-Correa JA et al. Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. 2007 Aug-Sep Vascul. Pharmacol. pmid:17581795
Ansari HR et al. Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17921329
Luceri C et al. p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo. 2007 Br. J. Nutr. pmid:17313706
Dawood MY and Khan-Dawood FS Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. 2007 Prostaglandins Other Lipid Mediat. pmid:17259081
Yang YY et al. Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis. 2007 Clin. Sci. pmid:17176248