Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Glomerulonephritis, Membranous D015433 6 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Wounds and Injuries D014947 20 associated lipids
Weil Disease D014895 2 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Zhang C et al. Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. 2004 J. Cardiovasc. Pharmacol. pmid:15071353
Brunkwall JS et al. Papaverine effects on PGI2 and TXA2 release from the canine vascular wall. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1508951
Arnold JH et al. Production of platelet thromboxane A2 and arterial prostacyclin I2 from hypercholesterolemic rats. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1508954
Evangelista V et al. Defibrotide inhibits platelet activation by cathepsin G released from stimulated polymorphonuclear leukocytes. 1992 Thromb. Haemost. pmid:1509406
Ishitsuka Y et al. Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. 2004 J. Pharm. Pharmacol. pmid:15099446
Leonhardt A et al. Reference intervals and developmental changes in urinary prostanoid excretion in healthy newborns, infants and children. 1992 Acta Paediatr. pmid:1511190
Caprani A et al. Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. 2004 Bioelectromagnetics pmid:15114641
Rabinovici R et al. Biological responses to exchange transfusion with liposome-encapsulated hemoglobin. 1992 Circ. Shock pmid:1511503
Di Minno G and Violi F Aspirin resistance and diabetic angiopathy: back to the future. 2004 Thromb. Res. pmid:15115664
Torsney E et al. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. 2004 Circ. Res. pmid:15117816
Ghuysen A et al. Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. 2004 J. Pharmacol. Exp. Ther. pmid:15121765
Akbiyik F et al. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. 2004 Blood pmid:15130939
Menzies-Gow NJ et al. Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. 2004 Equine Vet. J. pmid:15147137
Hammer C et al. Bridging to transplant: allogeneic heart transplantation after xenografting. 1992 Jul-Aug J. Heart Lung Transplant. pmid:1515437
Orosz L et al. Blood glucose and diabetic retinopathy. 1992 BMJ pmid:1515807
Gross GJ and Moore J Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. 2004 Pharmacology pmid:15161995
Suzuki N et al. Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. 2004 Prostaglandins Other Lipid Mediat. pmid:15165035
Nejad HH and Bottje WG Glutathione depletion and rabbit renal medulla 6-ketoPGF1 alpha and TxB2: levels in vivo and following homogenate incubation in vitro. 1992 Int. J. Biochem. pmid:1516728
Korkushko OV et al. [Some mechanisms of the development of endothelial disfunction in aging]. 2004 Fiziol Zh pmid:15174205
Kawano T et al. Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. 2004 Int. Arch. Allergy Immunol. pmid:15178893
Barbara J et al. Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. 2004 Clin. Exp. Allergy pmid:15196289
Wu KJ et al. [Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15196341
Riutta A et al. Solid-phase extraction of urinary 11-dehydrothromboxane B2 for reliable determination with radioimmunoassay. 1992 Anal. Biochem. pmid:1519756
Van Ryn J et al. Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. 2004 J Clin Pharmacol pmid:15199082
Imai T et al. [Role of thromboxane A2 and prostaglandin I2 in the increase of airway responsiveness in dogs after ozone exposure]. 1992 Arerugi pmid:1520068
Aikawa K et al. Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. 2004 Coron. Artery Dis. pmid:15201617
Barbieri SS et al. Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. 2004 Free Radic. Biol. Med. pmid:15203187
Goerig M et al. A new role for nicotine: selective inhibition of thromboxane formation by direct interaction with thromboxane synthase in human promyelocytic leukaemia cells differentiating into macrophages. 1992 Mar-Apr Clin Investig pmid:1521038
Kawada N et al. TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. 2004 Am. J. Physiol. Renal Physiol. pmid:15213069
Matsumoto Y et al. Effects of Y-20811, a thromboxane A2 synthetase inhibitor, on experimentally induced coronary thrombosis in anesthetized dogs. 1992 Eur. J. Pharmacol. pmid:1521557
Lorenzoni R et al. Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. 2004 Am. Heart J. pmid:15215815
Levin JH et al. Estradiol stimulates the secretion of prostacyclin and thromboxane from endometrial stromal cells in culture. 1992 Fertil. Steril. pmid:1521648
Harizi H et al. Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. 2004 Cell. Immunol. pmid:15219461
Meagher LC et al. Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2. 1992 J. Leukoc. Biol. pmid:1522386
Gu L et al. [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15224660
Kojima F et al. Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. 2004 Arthritis Res. Ther. pmid:15225371
Farndale RW et al. Measurement of platelet arachidonic acid metabolism. 2004 Methods Mol. Biol. pmid:15226540
Radvanyi-Hofmann H et al. Characterization of a thrombopathy (type delta storage pool disease) affecting a pig colony. 1992 Nouv Rev Fr Hematol pmid:1523094
Teng CM et al. Antiplatelet actions of some coumarin compounds isolated from plant sources. 1992 Thromb. Res. pmid:1523611
Singer P and Wirth M Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15253884
Barrière G et al. PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells. 2004 May-Jun Anticancer Res. pmid:15274299
Valeri CR et al. In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. 2004 J Trauma pmid:15280746
Heering P et al. The role of thromboxane and prostacyclin in ciclosporin-induced nephrotoxicity. 1992 Nephron pmid:1528337
Sheu JR et al. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. 2004 Br. J. Pharmacol. pmid:15289295
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Byrick RJ et al. Ibuprofen pretreatment does not prevent hemodynamic instability after cemented arthroplasty in dogs. 1992 Anesth. Analg. pmid:1530164
Ferroni P et al. Platelet activation in type 2 diabetes mellitus. 2004 J. Thromb. Haemost. pmid:15304032
Visioli F et al. Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. 2005 Eur J Nutr pmid:15309433
MacDermot J et al. The identity of IgE receptors (Fc epsilon RII) that mediate cellular activation of human macrophages: evidence against a role for CD23. 1992 Mol. Immunol. pmid:1530985
Craft JA et al. Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. 2004 Blood Coagul. Fibrinolysis pmid:15311156