Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
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Authors Title Published Journal PubMed Link
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Barton MH et al. Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. 1997 Am. J. Vet. Res. pmid:9361896
Baskett A et al. Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. 1997 Am. J. Vet. Res. pmid:9361895
Lahoz C et al. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. 1997 Eur. J. Clin. Invest. pmid:9352251
Neupert W et al. Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases. 1997 Br. J. Pharmacol. pmid:9351505
Supanz S et al. Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. 1997 Arzneimittelforschung pmid:9342416
Zahavi M and Zahavi J Concomitant in vitro platelet hypofunction and increased thromboxane B2 (TXB2) generation and enhanced in vivo platelet activation. A distinct syndrome in thrombosis? 1997 Eur. J. Haematol. pmid:9338626
Chavali SR et al. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. 1997 Int. Arch. Allergy Immunol. pmid:9338609
Hashimoto Y et al. Characteristics of protein kinase C-independent exocytosis in human platelets. 1997 Thromb. Res. pmid:9336873
Matrougui K et al. Impaired nitric oxide- and prostaglandin-mediated responses to flow in resistance arteries of hypertensive rats. 1997 Hypertension pmid:9336397
Moser L et al. ACE inhibitor effects on platelet function in stages I-II hypertension. 1997 J. Cardiovasc. Pharmacol. pmid:9335405
Uteshev DB and Uteshev BS [Adhesive molecules as drugs and objects of pharmacological effect in myocardial ischemia and reperfusion]. 1997 May-Jun Eksp Klin Farmakol pmid:9324410
Swails WS et al. Effect of a fish oil structured lipid-based diet on prostaglandin release from mononuclear cells in cancer patients after surgery. 1997 Sep-Oct JPEN J Parenter Enteral Nutr pmid:9323688
Berlin I et al. [Comparison between effects of morning and evening administration of effervescent calcium carbasalate (equivalent of 160 mg aspirin) on the gastroduodenal mucosa in healthy volunteers]. 1997 Pathol. Biol. pmid:9309270
Tanaka M et al. Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats. 1997 Biol. Neonate pmid:9303217
Abate A et al. Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. 1997 Inflamm. Res. pmid:9297549
Trang LE et al. Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. 1977 Scand. J. Rheumatol. pmid:929121
Cipollone F et al. Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina. 1997 Circulation pmid:9286937
Santillan-Doherty P et al. Plasma thromboxane B2 concentrations and pulmonary vascular resistance during lung reperfusion. 1997 Jul-Aug J Invest Surg pmid:9284000
Freese R and Mutanen M Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. 1997 Am. J. Clin. Nutr. pmid:9280178