Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Berg J et al. | Isoenzyme-specific cyclooxygenase inhibitors: a whole cell assay system using the human erythroleukemic cell line HEL and the human monocytic cell line Mono Mac 6. | 1997 | J Pharmacol Toxicol Methods | pmid:9279772 |
Lewis K et al. | Effect of neuropeptide Y on bradykinin-induced release of prostacyclin and thromboxane from guinea pig perfused lung. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9276148 |
Xing X and Xia S | [The injury of liver sinusoidal endothelial cells in a rat's isolated liver perfusion (ILP) model for regional chemotherapy]. | 1996 | Zhonghua Wai Ke Za Zhi | pmid:9275689 |
Ku K et al. | Influences of dietary omega-3 polyunsaturated fatty acids on the recovery of cardiac and renal functions after preservation in hyperlipidemic rats. | 1997 | Transplantation | pmid:9275102 |
Azevedo I et al. | Increased spontaneous release of tumour necrosis factor-alpha by alveolar macrophages from wheezy infants. | 1997 | Eur. Respir. J. | pmid:9272917 |
Chang TS et al. | Thromboxane A2 synthase inhibition and thromboxane A2 receptor blockade by 2-[(4-cyanophenyl)amino]-3-chloro-1,4-naphthalenedione (NQ-Y15) in rat platelets. | 1997 | Biochem. Pharmacol. | pmid:9271330 |
Serebruany VL et al. | Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor? | 1997 | Mol. Aspects Med. | pmid:9266521 |
De La Cruz JP et al. | Effects of S-adenosyl-L-methionine on platelet thromboxane and vascular prostacyclin. | 1997 | Biochem. Pharmacol. | pmid:9264331 |
Nanji AA et al. | Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9262373 |
Tulppala M et al. | Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production. | 1997 | Hum. Reprod. | pmid:9262298 |
Hishinuma T et al. | Microdetermination of the thromboxane B3 gas chromatography-selected-ion monitoring using [18O]thromboxane B3 as an internal standard. | 1997 | Prostaglandins | pmid:9261859 |
Slepko N et al. | Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture. | 1997 | J. Neurosci. Res. | pmid:9260740 |
Cenni E et al. | CD62, thromboxane B2, and beta-thromboglobulin: a comparison between different markers of platelet activation after contact with biomaterials. | 1997 | J. Biomed. Mater. Res. | pmid:9260099 |
van Kooten F et al. | Platelet activation and lipid peroxidation in patients with acute ischemic stroke. | 1997 | Stroke | pmid:9259748 |
Teng CM et al. | Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. | 1997 | J. Pharm. Pharmacol. | pmid:9255715 |
Brinkmann A et al. | The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction. | 1997 | Anesth. Analg. | pmid:9249099 |
Kotuliaková K et al. | Human polymorphonuclear leukocytes: effect of chloroquine on aggregation, arachidonic acid liberation and thromboxane B2 generation. | 1996 | Gen. Physiol. Biophys. | pmid:9248834 |
González E et al. | Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus. | 1997 | Prostaglandins | pmid:9247972 |
Szebeni J et al. | Complement activation and thromboxane secretion by liposome-encapsulated hemoglobin in rats in vivo: inhibition by soluble complement receptor type 1. | 1997 | Artif Cells Blood Substit Immobil Biotechnol | pmid:9242930 |
Johnson RD et al. | Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast. | 1997 | Am. J. Obstet. Gynecol. | pmid:9240586 |