Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Cheng WW and Zhang ZJ | [Low-dose aspirin preventing pregnancy induced hypertension]. | 1991 | Zhonghua Fu Chan Ke Za Zhi | pmid:1804603 |
Wang ZH | [Correlation between serotonin and prostaglandins in peritoneal fluid collected from patients with pelvic congestion]. | 1993 | Zhonghua Fu Chan Ke Za Zhi | pmid:8243156 |
Chen JS and Bi CQ | [Plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 levels in normal pregnancy and pregnancy-induced hypertension]. | 1988 | Zhonghua Fu Chan Ke Za Zhi | pmid:3383697 |
Shan MQ et al. | [Comparative study on effects of Rubiae Radix et Rhizoma and carbonized Rubiae Radix et Rhizoma on acute blood stasis rat model]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:24946554 |
Ma K et al. | [Study on comparative pharmacology of series of Muskone]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17061560 |
Fu JH et al. | [Protective effects of saponines of stem and leaf of Panax notoginseng on acute myocardial ischemia in anaesthetic dogs]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:16548173 |
Gu L et al. | [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. | 2003 | Zhongguo Zhong Yao Za Zhi | pmid:15224660 |
Lu G et al. | [Effect of xueling on relating substances of renal hypertension in rats]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11601304 |
Zhu S et al. | [Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16161448 |
Zhang JY et al. | [Study on therapeutic effects of series of muskone on myocardial infarction canines]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17225541 |
Li XM et al. | [Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17672345 |
Liu P et al. | [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15631091 |
Yan Y et al. | [Study on mechanism of eye-signs in blood stasis syndrome]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9206243 |
Wang SR et al. | [Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8339039 |
Liu ZQ et al. | [Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577356 |
Lin CL et al. | [Therapeutic mechanism of combination therapy of ligustrazine and nitrendipine in treating patients with chronic obstructive pulmonary disease]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577373 |
Yan DH et al. | [Study on experimental parameters for diagnosing ganyang huafeng syndrome of cerebral infarction]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9772617 |
Tang QZ et al. | [Effect of buyang huanwu decoction on platelet function and fibrinolytic activity of unstable angina pectoris patients]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322871 |
Chen SX et al. | [Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322873 |
Wu Y et al. | [Clinical study on improving effect of Buyang Huanwu decoction on plasma thromboxane B2, 6-keto-prostaglandin F1 alpha, endothelin and calcitonin gene related peptide in primary nephrotic syndrome patients]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11475715 |
Lang J et al. | [Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11475719 |
Lin S et al. | [Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477811 |
Huang R et al. | [Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477904 |
Liang XC et al. | [Study on relationship of lipid peroxide in coronary heart disease with and without diabetes]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732128 |
Xu J et al. | [Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477921 |
Liang-min LD et al. | [Effect of age on hemostasis and plasma level of TXB2 and 6-keto-PGF1 alpha]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732148 |
Li H | [Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732157 |
Gu MJ and Liu ZM | [Prevention of toxicity of cyclosporine A on rat pancreatic islet beta-cells by Ligustrazine]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8111213 |
Hu WL and Ma YJ | [Effect of glycerol-induced acute renal failure in rabbit with Ligusticum wallichii on thromboxane B2, 6-keto-prostaglandin F1 alpha/thromboxane B2]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8111216 |
Wang S et al. | [Effects of ligustrazine on plasma platelet aggregation rate, thromboxane B2, 6-keto-prostaglandin F1 alpha and von Willebrand's factor in patients with acute onset of cor pulmonale]. | 1999 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11783174 |
Zhou X et al. | [Clinical and experimental study on effect of Shuguan granule on mid-late rheumatoid arthritis]. | 1999 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11783301 |
Hu Z et al. | [Experimental study of influence of yiqi huoxue serial recipes on basement membrane in membranous nephritis in rabbits]. | 1999 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11783306 |
Xu X et al. | [Relation between traditional Chinese medicinal syndrome differentiation and blood platelet function in 310 cases of blood stasis]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8136643 |
Xu L et al. | [Clinical and experimental study on effect of Chanbei Kechuanping in treating bronchial asthma]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789166 |
Wei J et al. | [Clinical and experimental study on effects of ji shen mixture for infantile acute glomerulonephritis]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8136648 |
Han G et al. | [Inhibitory effect of panicoin on platelet activation and its mechanism]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789213 |
Yang SX et al. | [Comparison of lipoperoxidative damage in plasma and platelet with the ratio of thromboxane A2 and prostaglandin I2 in blood stasis syndrome with coronary heart disease]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8155941 |
Song WD et al. | [Relationship between local effect of cortisol used by chronic bronchitis patients and syndrome differentiation in TCM]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719090 |
Wang XM et al. | [Study on advanced non-small cell lung cancer patients with Qi deficiency and blood stasis syndrome]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719106 |
Zhang T et al. | [Clinical observation on preventing and treating coronary atherosclerotic heart disease with tongmai jiangzhi oral liquid]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11367649 |
Deng CQ et al. | [Comparison of effect of Astragalus membranaceus and huoxuefang on thromboxane, prostacyclin and adenosine cyclic monophosphate in cerebral reperfusion injury in rabbits]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7647534 |
Jiang HW et al. | [Clinical study in treating qi-deficiency and blood-stasis syndrome of angina pectoris with qi xue granule]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1301847 |
Bao YM et al. | [Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:21066890 |
Gao L et al. | [Effects of supplementing qi and activating blood circulation method on platelet aggregation rate, adhesion rate and thromboxane B2 level in patients with stable angina pectoris and intolerable to aspirin]. | 2008 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:18543479 |
Zhu PJ | [Therapeutic changes in nephrotic syndrome treated with yiqi huoxue jiedu decoction and corticosteroid]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1477504 |
Jin YQ and Li XQ | [Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8251718 |
Sang Y et al. | [Effects of tangshenkang capsule on diabetic nephropathy]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9387731 |
Wang JW et al. | [Effects of puerarin on the vascular active factor related to cerebral vasospasm after aneurysm subarachnoid hemorrhage]. | 2012 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:22574584 |
Han JA and Hu WY | [Progress in the study on protective effect of saponins Panax notoginseng on ischemic brain damage]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9387754 |
Lu CS et al. | [Experimental study on anti-atherosclerotic effect of tongmai jiangzhi oral liquor]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8580696 |
Wang CH et al. | [Clinical and experimental study on effect of Chinese herbal drugs on producing prostaglandin in gastric mucosa]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7865999 |
Wang Z et al. | [Clinical and experimental study on treatment of bronchial asthma with pingchuan oral liquid]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938808 |
Liu XH et al. | [Study of anti-cerebral thromboembolism injection's activity on experimental arterial thrombosis and its therapeutical mechanism]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7580067 |
Yu K et al. | [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938829 |
Shi X et al. | [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938858 |
Wang XP et al. | [Therapeutic effects and mechanisms of tetramethylpyrazine on lung injury in acute haemorrhagic necrotizing pancreatitis in rats]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8312699 |
Miao X et al. | [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938860 |
Ding Q | [Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1392491 |
Zhou Q | [Experimental study of atherosclerosis and cholelithiasis with the same treatment. I. Effects of yiqi huoxue and shugan liqi agents in atherosclerosis of rabbit]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1392494 |
Huang RJ et al. | [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764908 |
Sun ZT et al. | [Clinical and experimental study on treating bronchial asthma with xingbei granule]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863090 |
Li ZG et al. | [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764922 |
Zhang XY and Qian XM | [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863112 |
Wu JX et al. | [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863132 |
Fu CJ et al. | [Effect of ligustrazine on isolated myocardial ischemic reperfusion injury in rats]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8400774 |
Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |
Shao CR et al. | [Clinical and experimental study on Ligusticum wallichii mixture in preventing and treating bronchial asthma]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7841753 |
Chen BN et al. | [Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities]. | 2004 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:15495823 |
Zhu F et al. | [Experimental study on anti-inflammatory and analgesic effects of electroacupuncture combined with medium frequency therapy in model rats with lumbar nerve root compression]. | 2011 | Zhongguo Zhen Jiu | pmid:21894700 |
Zeng HH et al. | [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186611 |
Wang Z et al. | [Na [125I]-labelled 6-keto-PGF1 alpha and thromboxane B2]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2943448 |
Wang Z | [Radioimmunoassay of thromboxane B2]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2944644 |
Wang Z et al. | [Preliminary report on the application of thromboxane B2 radioimmunoassay]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2953485 |
Wang L and Wang Z | [The effects of ilexonin A on AA metabolism]. | 1991 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:1831714 |
Xiao D | [Inhibition of phorbol ester and A23187-stimulated prostaglandins synthesis in macrophages by anisodamine]. | 1990 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2147587 |
Yu Y et al. | [Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats]. | 1998 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:11367732 |
Lin Y and Sun M | [Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase]. | 1995 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:8575046 |
Qu C et al. | Effect of fenofibrate on the secretion of endothelium-derived contracting factors in hypertensive rats. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:22776656 |
Li H | [The effects of electro-acupuncture on exudate volume and TXB2, 6-keto-PGF1 alpha content in the pleural cavity after carrageenin-induced pleurisy in rats]. | 1987 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2964932 |
Xu SH | [Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH]. | 1988 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2978253 |
Wang YL et al. | Effect of ubiquinone on ischemic arrhythmia in conscious rats. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781279 |
Wang Z et al. | [Sodium ferulate is an inhibitor of thromboxane A2 synthetase]. | 1988 | Zhongguo Yao Li Xue Bao | pmid:3218538 |
Fu JM et al. | [Effects of oxyfedrine on platelet thromboxane A2 and aorta prostacyclins formations]. | 1988 | Zhongguo Yao Li Xue Bao | pmid:3218539 |
Rui YC et al. | [Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2128432 |
Fang YX et al. | Beneficial changes in prostacyclin and thromboxane A2 induced by ginsenosides in myocardial infarction and reperfusion injury in dogs. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2954367 |
Chu GX and Chen X | Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2275384 |
Zhang YL et al. | [Protective action of sophoridine on acute myocardial infarction in anesthetized dogs]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781291 |
Ren YJ et al. | Inhibitory effects of nimodipine on platelet aggregation and thrombosis. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374642 |
Shan CW et al. | Inhibitory effects of procainamide on rabbit platelet aggregation and thromboxane B2 production in vitro. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374644 |
Zhang P et al. | [Effects of methylflavonolamine on TXA2 and PGI2 plasma levels in rabbits with myocardial infarction]. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8237408 |
Zhang PW et al. | Influence of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on vascular endothelial epoprostenol and platelet aggregation. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7660825 |
Du ZY and Huang YH | Effects of tetrandrine on production of leukotriene B4 and thromboxane B2 in rabbit blood. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8249626 |
Xiao D et al. | Effects of quercetin on platelet and reperfusion-induced arrhythmias in rats. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8010047 |
Xuan B et al. | Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. | 1994 | Zhongguo Yao Li Xue Bao | pmid:8010106 |
Sun XM et al. | [Effect of 2-naphthyl-3- (3,4-dimethoxy) phenyl-propenoic acid on the metabolism of arachidonic acid in rabbit platelets]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2403015 |
Rui YC et al. | [Effect of dazoxiben on cerebrovascular resistance in rabbits]. | 1989 | Zhongguo Yao Li Xue Bao | pmid:2624120 |
Wang YZ et al. | Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7597920 |
Chen XS et al. | Effects of CI-930, a novel phosphodiesterase III inhibitor, on platelet aggregation and arachidonic acid metabolism. | 1990 | Zhongguo Yao Li Xue Bao | pmid:1966575 |
Jiang YY et al. | [Effects of econazole and clotrimazole on TXB2 and PGE2 production in calcimycin-stimulated neutrophils and arachidonic acid-stimulated platelets]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781294 |
Huang CG et al. | [Effects of berberine on synthesis of platelet TXA2 and plasma PGI2 in rabbits]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1824005 |