Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Pallio G et al. Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis. 2016 Eur. J. Pharmacol. pmid:27450484
Peng LL et al. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. 2016 Acta Pharmacol. Sin. pmid:27641736
Maga P et al. 11-dehydro thromboxane B2 levels after percutaneous transluminal angioplasty in patients with peripheral arterial occlusive disease during a one year follow-up period. 2016 J. Physiol. Pharmacol. pmid:27511998
Morel A et al. The increased level of COX-dependent arachidonic acid metabolism in blood platelets from secondary progressive multiple sclerosis patients. 2016 Mol. Cell. Biochem. pmid:27507559
Olszowski T et al. The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages. 2015 Biol Trace Elem Res pmid:25645360
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Liu TF et al. [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. 2015 Beijing Da Xue Xue Bao pmid:26679651
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Lüdicke F et al. A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers. 2015 Biomarkers pmid:26616146
Di Minno MN et al. Increased platelet reactivity in Klinefelter men: something new to consider. 2015 Andrology pmid:26216452
Gavriilaki E et al. Platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857917
Véricel E et al. Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. 2015 Thromb. Haemost. pmid:25832443
Khanna V et al. Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? 2015 J. Thromb. Haemost. pmid:25809653
Wu F et al. Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension. 2015 Chin. Med. J. pmid:25591555
Paikin JS et al. Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial. 2015 J. Thromb. Haemost. pmid:25546465
Bautista-Pérez R et al. Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. 2015 Am. J. Physiol. Renal Physiol. pmid:25354938
Drew RC et al. Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26371168