Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Heidemann SM et al. | Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359020 |
Mita H et al. | Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359019 |
Spokas EG et al. | Whole-blood assays for evaluation of thromboxane synthase inhibition. | 1999 | Methods Mol. Biol. | pmid:10343321 |
Stanczyk FZ et al. | Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers. | 1999 | Contraception | pmid:10342082 |
Tegeder I et al. | Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. | 1999 | Clin. Pharmacol. Ther. | pmid:10340919 |
Ishihara S et al. | Effects of long-term hemofiltration on circulating mediators and superoxide production during continuous endotoxin administration. | 1999 | J Trauma | pmid:10338409 |
Davis KA et al. | Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusion. | 1999 | J Trauma | pmid:10338399 |
Liguori A et al. | Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10335906 |
Salomon P and Halawa B | [Levels of neuropeptide Y and thromboxane B2 in patients with variant angina]. | 1998 | Pol. Arch. Med. Wewn. | pmid:10335040 |
Kanji VK et al. | Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. | 1999 | Transplant. Proc. | pmid:10331052 |