Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Fibrosis D005355 23 associated lipids
Hypoxia D000860 23 associated lipids
Pulmonary Edema D011654 23 associated lipids
Birth Weight D001724 23 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Anemia D000740 21 associated lipids
Myocardial Infarction D009203 21 associated lipids
Helicobacter Infections D016481 21 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Pleurisy D010998 20 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Singh D et al. Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. 1981 Am. J. Hematol. pmid:6274189
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Webb PJ et al. Do prostacyclin and thromboxane play a role in endotoxic shock? 1981 Br J Surg pmid:7025959
Parks WM et al. Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. 1981 J. Pharmacol. Exp. Ther. pmid:7026767
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Roselló J et al. Quantitative profiling of the metabolic cascade of arachidonic acid by capillary gas chromatography mass spectrometry. 1981 Biomed. Mass Spectrom. pmid:7236862
Stuart MJ Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. 1981 Am. J. Hematol. pmid:7030066
Dembélé-Duchesne MJ et al. Some new prospects in the mechanism of control of arachidonate metabolism in human placenta and amnion. 1981 Prostaglandins pmid:6801732
Cook JA et al. Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. 1981 Circ. Shock pmid:7237685
Lorenz R et al. Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. 1981 Eur. J. Pharmacol. pmid:7238575
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Townsend ER et al. Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. 1981 Circ. Res. pmid:7249281
McCann DS et al. Radioimmunoassay for plasma thromboxane B2. 1981 Clin. Chem. pmid:7273401
Gilani SH and Persaud TV Embryopathic effects of thromboxane B2 in the chick. 1981 Prostaglandins Med pmid:7267828
Anderson CB et al. Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. 1981 Transplant. Proc. pmid:7268892
Coker SJ et al. Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. 1981 Nature pmid:6894485
Bishai I and Coceani F Transformations of prostaglandin H2 in the cat brain. 1981 Biochim. Biophys. Acta pmid:6894549
Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Halushka PV et al. Protective effects of aspirin in endotoxic shock. 1981 J. Pharmacol. Exp. Ther. pmid:6894770
Feuerstein N et al. Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. 1981 Br. J. Pharmacol. pmid:6894882
Karmazyn M et al. Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage. 1981 J. Pharmacol. Exp. Ther. pmid:6894943
Seitz M et al. The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. 1981 Agents Actions pmid:7340450
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Grimm LJ et al. Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation. 1981 Thromb. Res. pmid:6801806
Worthington RE and Nakeff A Thromboxane synthesis in megakaryocytes isolated by centrifugal elutriation. 1981 Blood pmid:6786393
Igarashi K et al. Effect of polyamines on prostaglandin synthesis in various cell-free systems. 1981 Biochem. Biophys. Res. Commun. pmid:6800368
Landgraf-Leurs MM et al. Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. 1981 Prostaglandins pmid:6798637
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
Galli C et al. Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. 1980 Prog Food Nutr Sci pmid:6779348
Best LC et al. Studies on the role of calcium in the control of thromboxane B2 production. 1980 Artery pmid:6783015
Crutchley DJ et al. Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. 1980 Am. Rev. Respir. Dis. pmid:6155814
Patrono C et al. Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. 1980 Agents Actions Suppl. pmid:6787852
Cella G et al. In vivo platelet release reaction in patients with heart valve prosthesis. 1980 Haemostasis pmid:6157609
Silver MJ et al. A model system for studying initial events in atherosclerosis. 1980 Artery pmid:7000044
Best LC et al. Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. 1980 Biochim. Biophys. Acta pmid:6251913
Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
Poyser NL and Scott FM Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. 1980 J. Reprod. Fertil. pmid:7001011
Lands WE et al. Recent concepts on platelet function and dietary lipids in coronary thrombosis, vasospasm and angina. 1980 Herz pmid:7007191
Subbiah MT et al. Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. 1980 Pharmacology pmid:7220591
Ali AE et al. Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. 1980 Prostaglandins pmid:7008090
Ohtsu E and Matsuzawa T Metabolic alterations in the endogenous formation of 6 keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in the brain-stem of stroke-resistant spontaneously hypertensive rats. 1980 J. Nutr. Sci. Vitaminol. pmid:7229740
Vargaftig BB et al. Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. 1980 Eur. J. Pharmacol. pmid:7009169
Giri SN and Krishna GA Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. 1980 J Pharmacol Methods pmid:7009992
Zapol WM et al. Plasma thromboxane and prostacyclin metabolites in sheep partial cardiopulmonary bypass. 1980 Trans Am Soc Artif Intern Organs pmid:7018060
Güllner HG et al. Correction of increased prostacyclin production in Bartter's syndrome by indomethacin. 1980 Trans. Assoc. Am. Physicians pmid:7018063
Wise WC et al. Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock. 1980 Circ. Res. pmid:7189697
Zamecnik J et al. Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. 1980 Adv Prostaglandin Thromboxane Res pmid:6990719
Frame MH et al. Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. 1980 Adv Prostaglandin Thromboxane Res pmid:6990724
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Jécsai G and Bagdány S Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. 1980 Acta Biochim. Biophys. Acad. Sci. Hung. pmid:7282294
Hwang DH Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. 1980 Prostaglandins Med pmid:7413850
Cerskus AL et al. Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone. 1980 Thromb. Res. pmid:7414555
Tada M et al. Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease. 1980 Adv Myocardiol pmid:7423053
Matsumoto M et al. Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. 1980 Thromb. Haemost. pmid:7423441
Davies GC et al. Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass. 1980 Circulation pmid:6965618
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Galli C et al. Modulation of prostaglandin production in tissues by dietary essential fatty acids. 1980 Acta Med. Scand. Suppl. pmid:6935943
Wong PY et al. The role of calmodulin in prostaglandin metabolism. 1980 Ann. N. Y. Acad. Sci. pmid:6940495
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Güllner HG et al. The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. 1980 Adv Prostaglandin Thromboxane Res pmid:6892749
Liggins GC et al. Production rates of prostaglandin F, 6-keto-PGF1 alpha and thromboxane B2 by perifused human endometrium. 1980 Prostaglandins pmid:6892962
Subbiah MT and Dietemeyer D Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats. 1980 Biochem Med pmid:6893150
Dupont J et al. Effects of dietary essential fatty acid concentration upon prostanoid synthesis in rats. 1980 J. Nutr. pmid:7400858
Rao GH et al. Influence of epinephrine on the aggregation response of aspirin-treated platelets. 1980 Prostaglandins Med pmid:7403340
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Hassid A and Dunn MJ Microsomal prostaglandin biosynthesis of human kidney. 1980 J. Biol. Chem. pmid:7358683
Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Van Praag D and Farber SJ Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. 1980 Adv Prostaglandin Thromboxane Res pmid:7369029
Kot PA et al. Modification of the cardiovascular actions of prostaglandins by thromboxane B2. 1980 Adv Prostaglandin Thromboxane Res pmid:7369035
Gorman RR Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. 1980 Adv Prostaglandin Thromboxane Res pmid:6247892
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lewy RI Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. 1980 Haemostasis pmid:7372200
Bishai I and Coceani F Metabolism of PGH2 in the feline brain. 1980 Adv Prostaglandin Thromboxane Res pmid:7376980
Galli C et al. Factors affecting brain prostaglandin formation. 1980 Adv Prostaglandin Thromboxane Res pmid:7376983
Blotman F et al. PGE2, PGF2 alpha, and TXB2 biosynthesis by human rheumatoid synovia. 1980 Adv Prostaglandin Thromboxane Res pmid:7377017
Powell WS Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. 1980 Prostaglandins pmid:6258197
Katori M et al. Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. 1980 Adv Prostaglandin Thromboxane Res pmid:7377020
Crutchley DJ et al. Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. 1980 Adv Prostaglandin Thromboxane Res pmid:7377022
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Hwang DW et al. Species variation in serum levels of prostaglandins and their precursor acids. 1980 Lipids pmid:7432104
Bolton HS et al. Prostaglandin synthesis by adult heart myocytes. 1980 J. Mol. Cell. Cardiol. pmid:7441771
Dejana E et al. Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats. 1980 Br. J. Haematol. pmid:7448129
Subbiah MT et al. Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. 1980 Thromb. Haemost. pmid:7455983
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751
Lewy RI et al. Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. 1980 Circulation pmid:7371128
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618
Best LC et al. The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets. 1980 Clin. Sci. pmid:7190885
Heggers JP et al. Histological demonstration of prostaglandins and thromboxanes in burned tissue. 1980 J. Surg. Res. pmid:6987462
Meyers KM et al. An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. 1980 Thromb. Res. pmid:7209869