Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Chiba Y et al. Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass. 1998 Ann. Thorac. Surg. pmid:9456104
Erez E et al. Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin? 1998 Ann. Thorac. Surg. pmid:9456103
Yanagisawa H et al. Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys. 1997 Kidney Blood Press. Res. pmid:9453451
Parra T et al. Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. 1998 J. Lab. Clin. Med. pmid:9452128
Moore RM et al. Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. 1998 Jan-Feb Vet Surg pmid:9449176
Dent G et al. Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9448055
Snapper JR et al. Role of endothelin in endotoxin-induced sustained pulmonary hypertension in sheep. 1998 Am. J. Respir. Crit. Care Med. pmid:9445282
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Sorem KA and Siler-Khodr TM Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation. 1997 Nov-Dec J Matern Fetal Med pmid:9438218
Sheu JR et al. Triflavin inhibits platelet-induced vasoconstriction in de-endothelialized aorta. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9437193
Qureshi MA and Gore AB Vitamin E exposure modulates prostaglandin and thromboxane production by avian cells of the mononuclear phagocytic system. 1997 Immunopharmacol Immunotoxicol pmid:9436047
Akarsu ES et al. Effect of ciliary neurotrophic factor on body temperature and cerebrospinal fluid prostanoids in the cat. 1998 Brain Res. Bull. pmid:9434196
Famaey JP In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. 1997 Inflamm. Res. pmid:9427063
Gresele P et al. Platelet activation markers in patients with peripheral arterial disease--a prospective comparison of different platelet function tests. 1997 Thromb. Haemost. pmid:9423790
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Oosaki R et al. Urinary excretion of leukotriene E4 and 11-dehydrothromboxane B2 in patients with spontaneous asthma attacks. 1997 Int. Arch. Allergy Immunol. pmid:9414142
Alanko J et al. Catechol estrogens as inhibitors of leukotriene synthesis. 1998 Biochem. Pharmacol. pmid:9413936
Davì G et al. Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group. 1997 Am. J. Respir. Crit. Care Med. pmid:9412557
Gerdemann R et al. [Effect of flunixin meglumine on plasma prostanoid concentrations in horses with colic in the perioperative period]. 1997 DTW. Dtsch. Tierarztl. Wochenschr. pmid:9410724
Davi G et al. In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409316