Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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DeFilippis AP et al. | Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24370448 |
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Kim TW et al. | Evaluation of pharmacokinetic and pharmacodynamic properties of cimicoxib in fasted and fed horses. | 2015 | N Z Vet J | pmid:25075617 |
Pinto FC et al. | Effect of volume replacement during combined experimental hemorrhagic shock and traumatic brain injury in prostanoids, brain pathology and pupil status. | 2015 | Arq Neuropsiquiatr | pmid:26083885 |
Liu TF et al. | [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. | 2015 | Beijing Da Xue Xue Bao | pmid:26679651 |
Holland B et al. | Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25378135 |
Lüdicke F et al. | A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers. | 2015 | Biomarkers | pmid:26616146 |
Di Minno MN et al. | Increased platelet reactivity in Klinefelter men: something new to consider. | 2015 | Andrology | pmid:26216452 |
Ryu R et al. | Ethanol Extract of Persimmon Tree Leaves Improves Blood Circulation and Lipid Metabolism in Rats Fed a High-Fat Diet. | 2015 | J Med Food | pmid:26061228 |
Larsen SB et al. | Determinants of reduced antiplatelet effect of aspirin in patients with stable coronary artery disease. | 2015 | PLoS ONE | pmid:25993271 |
Paikin JS et al. | Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial. | 2015 | J. Thromb. Haemost. | pmid:25546465 |
Bautista-Pérez R et al. | Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25354938 |
Drew RC et al. | Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26371168 |