Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Canales A et al. | The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype. | 2010 Sep-Oct | Nutr Hosp | pmid:21336431 |
Maddens BE et al. | Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. | 2010 | Vet. Immunol. Immunopathol. | pmid:19815297 |
Derhaschnig U et al. | Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia. | 2010 | Platelets | pmid:20608787 |
Cheng Y and Li ZK | [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. | 2010 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:20584647 |
Boutaud O and Oates JA | Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. | 2010 | Methods Mol. Biol. | pmid:20645166 |
Kawaguchi T et al. | The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. | 2010 | Cell Biol. Int. | pmid:20522022 |
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Butler BD et al. | Circadian study of decompression sickness symptoms and response-associated variables in rats. | 2010 | Chronobiol. Int. | pmid:20205563 |
Boizel R et al. | Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes. | 2010 | Diabetologia | pmid:20535444 |
Liu H et al. | Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. | 2010 | Cardiovasc Drugs Ther | pmid:19997773 |
Cavalca V et al. | Simultaneous quantification of 8-iso-prostaglandin-F(2alpha) and 11-dehydro thromboxane B(2) in human urine by liquid chromatography-tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:19825360 |
Fukushima H et al. | Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. | 2010 | Am. J. Med. Genet. A | pmid:20583254 |
Sato R et al. | Inhibition of secretory phospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model. | 2010 | Exp. Lung Res. | pmid:20426527 |
Ferrante E et al. | Determinants of thromboxane biosynthesis in rheumatoid arthritis: Role of RAGE and oxidant stress. | 2010 | Free Radic. Biol. Med. | pmid:20541603 |
Hepgül G et al. | Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. | 2010 | Dig. Dis. Sci. | pmid:19294507 |
Iwasaki W et al. | Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. | 2010 | Shock | pmid:19543146 |
Yen PL et al. | Effects of deep-frying oil on blood pressure and oxidative stress in spontaneously hypertensive and normotensive rats. | 2010 | Nutrition | pmid:19592221 |
Huntjens DR et al. | Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. | 2010 | Eur J Pain | pmid:19679500 |
Addad F et al. | Response variability to aspirin and one-year prediction of vascular events in patients with stable coronary artery disease. | 2010 | J. Thromb. Thrombolysis | pmid:19381450 |