Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pleurisy D010998 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Anemia D000740 21 associated lipids
Myocardial Infarction D009203 21 associated lipids
Helicobacter Infections D016481 21 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypoxia D000860 23 associated lipids
Fibrosis D005355 23 associated lipids
Pulmonary Edema D011654 23 associated lipids
Birth Weight D001724 23 associated lipids
Cattle Diseases D002418 24 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hyperemia D006940 25 associated lipids
Ascites D001201 25 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Nasal Polyps D009298 26 associated lipids
Endotoxemia D019446 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Gastritis D005756 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Endometriosis D004715 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Proteinuria D011507 30 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Stroke D020521 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Uremia D014511 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Burns D002056 34 associated lipids
Anaphylaxis D000707 35 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Fever D005334 35 associated lipids
Heart Failure D006333 36 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Lung Diseases D008171 37 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Hypotension D007022 41 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Canales A et al. The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype. 2010 Sep-Oct Nutr Hosp pmid:21336431
Maddens BE et al. Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. 2010 Vet. Immunol. Immunopathol. pmid:19815297
Derhaschnig U et al. Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia. 2010 Platelets pmid:20608787
Cheng Y and Li ZK [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. 2010 Nan Fang Yi Ke Da Xue Xue Bao pmid:20584647
Boutaud O and Oates JA Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. 2010 Methods Mol. Biol. pmid:20645166
Kawaguchi T et al. The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. 2010 Cell Biol. Int. pmid:20522022
Alusik S et al. The inhibitory effect of statins on urinary 11-dehydrothromboxane levels. 2010 Int Angiol pmid:20502413
Mangalpally KK et al. Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. 2010 J. Thromb. Thrombolysis pmid:20502945
Butler BD et al. Circadian study of decompression sickness symptoms and response-associated variables in rats. 2010 Chronobiol. Int. pmid:20205563
Boizel R et al. Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes. 2010 Diabetologia pmid:20535444
Liu H et al. Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. 2010 Cardiovasc Drugs Ther pmid:19997773
Cavalca V et al. Simultaneous quantification of 8-iso-prostaglandin-F(2alpha) and 11-dehydro thromboxane B(2) in human urine by liquid chromatography-tandem mass spectrometry. 2010 Anal. Biochem. pmid:19825360
Fukushima H et al. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. 2010 Am. J. Med. Genet. A pmid:20583254
Sato R et al. Inhibition of secretory phospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model. 2010 Exp. Lung Res. pmid:20426527
Ferrante E et al. Determinants of thromboxane biosynthesis in rheumatoid arthritis: Role of RAGE and oxidant stress. 2010 Free Radic. Biol. Med. pmid:20541603
Hepgül G et al. Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. 2010 Dig. Dis. Sci. pmid:19294507
Iwasaki W et al. Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. 2010 Shock pmid:19543146
Yen PL et al. Effects of deep-frying oil on blood pressure and oxidative stress in spontaneously hypertensive and normotensive rats. 2010 Nutrition pmid:19592221
Huntjens DR et al. Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. 2010 Eur J Pain pmid:19679500
Addad F et al. Response variability to aspirin and one-year prediction of vascular events in patients with stable coronary artery disease. 2010 J. Thromb. Thrombolysis pmid:19381450