Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gossmann J et al. | Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? | 2001 | Kidney Blood Press. Res. | pmid:11435743 |
Dubé JN et al. | Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder. | 2001 | Br. J. Haematol. | pmid:11442478 |
Tran HS et al. | Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. | 2001 | Crit. Care Med. | pmid:11445706 |
Coelho-Filho OR et al. | Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. | 2001 | Int. J. Cardiol. | pmid:11461744 |
Wojakowski W and Gmiński J | Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease. | 2001 | Scand. J. Clin. Lab. Invest. | pmid:11465346 |
Rosón MI et al. | Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions. | 2001 | Arch. Physiol. Biochem. | pmid:11471069 |
Catella-Lawson F et al. | Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. | 2001 | Am. J. Cardiol. | pmid:11472700 |
Zoja C et al. | Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis. | 2001 | Kidney Int. | pmid:11473648 |
Wu Y et al. | [Clinical study on improving effect of Buyang Huanwu decoction on plasma thromboxane B2, 6-keto-prostaglandin F1 alpha, endothelin and calcitonin gene related peptide in primary nephrotic syndrome patients]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11475715 |
Lang J et al. | [Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11475719 |
Lin S et al. | [Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477811 |
Huang R et al. | [Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477904 |
Xu J et al. | [Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11477921 |
Urquhart P et al. | Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487303 |
Rebrov BA | [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. | 2001 Mar-Apr | Urologiia | pmid:11490711 |
Valeri CR et al. | Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. | 2001 | Transfusion | pmid:11493727 |
Khan HH et al. | Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. | 2000 | Acta Pharmacol. Sin. | pmid:11501061 |
Chen G et al. | [The effect of the molecular triggers of hemostatic activity on thrombosis in early stage of electrical injuries]. | 1999 | Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi | pmid:11501103 |
Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
Ploner F et al. | Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs. | 2001 | Shock | pmid:11508865 |