Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Brown C et al. | Effects of age and steroid treatment on prostaglandin production by the rat uterus in relation to implantation. | 1984 | J. Reprod. Fertil. | pmid:6583409 |
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Schenkein HA and Rutherford RB | Effects of serum on C3b-stimulated release of prostaglandins and thromboxane B2 from human monocytes. | 1984 | Immunopharmacology | pmid:6511367 |
Fung WP et al. | Effect of ethanol on gastric secretion of thromboxane B2. | 1984 | Med. J. Malaysia | pmid:6513851 |
Watanabe J et al. | Effect of prostaglandin synthetase inhibitors on platelet aggregation and thromboxane production in diabetes mellitus. | 1984 | Tohoku J. Exp. Med. | pmid:6515648 |
Ditter H and Matthias FR | Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. | 1984 | VASA | pmid:6516562 |
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Block HU et al. | Estimation of thromboxane B2 in the clotting human whole blood by gas chromatography. | 1984 | Biomed. Biochim. Acta | pmid:6517904 |
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Keinänen-Kiukaanniemi S et al. | Decreased thromboxane production in migraine patients during headache-free period. | 1984 | Headache | pmid:6519984 |
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Hornych A et al. | [Changes in plasma prostaglandins in normal subjects in an orthostatic position. Comparison with the response of the renin-aldosterone system]. | 1984 | Presse Med | pmid:6242503 |
Lampugnani MG and de Gaetano G | Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. | 1984 | Am. J. Physiol. | pmid:6433724 |
Koike K et al. | Platelet secretion defect in patients with the attention deficit disorder and easy bruising. | 1984 | Blood | pmid:6692042 |
Vesterqvist O et al. | Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. | 1984 | Thromb. Res. | pmid:6695361 |
Davì G et al. | Platelet function changes in acute myocardial infarction. | 1984 | Adv. Exp. Med. Biol. | pmid:6695571 |
Mehta J et al. | Thromboxane release in coronary artery disease: spontaneous versus pacing-induced angina. | 1984 | Am. Heart J. | pmid:6695662 |
Klotz TA et al. | Urinary excretion of thromboxane B2 in patients with venous thromboembolic disease. | 1984 | Chest | pmid:6697787 |
Maddox Y et al. | A routine source of human peritoneal macrophages. | 1984 | Scand. J. Immunol. | pmid:6701470 |
Schieppati A et al. | The metabolism of arachidonic acid by platelets in nephrotic syndrome. | 1984 | Kidney Int. | pmid:6434788 |
Lefkowith JB et al. | Macrophage-dependent arachidonate metabolism in hydronephrosis. | 1984 | Kidney Int. | pmid:6434790 |
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Ditter H et al. | Comparison of sympathomimetic amines with collagen, calcium ionophor and adenosine diphosphate in their effects on thromboxane formation of human platelet rich plasma. | 1984 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:6083951 |
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Goldyne ME | Heterogeneity in leukocyte preparations: effects on defining eicosanoid metabolism by human lymphocytes and monocytes. | 1984 | J. Allergy Clin. Immunol. | pmid:6088610 |
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Burch RM and Halushka PV | Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder. | 1984 | Arch. Biochem. Biophys. | pmid:6422855 |
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Pedersen AK and FitzGerald GA | Dose-related kinetics of aspirin. Presystemic acetylation of platelet cyclooxygenase. | 1984 | N. Engl. J. Med. | pmid:6436696 |