Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jiang J et al. | Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on Major Eicosanoids: A Systematic Review and Meta-Analysis from 18 Randomized Controlled Trials. | 2016 | PLoS ONE | pmid:26808318 |
Santilli F et al. | Pentraxin 3 and Platelet Activation in Obese Patients After Gastric Banding. | 2016 | Circ. J. | pmid:26632534 |
Mayer AM et al. | Classical and Alternative Activation of Cyanobacterium Oscillatoria sp. Lipopolysaccharide-Treated Rat Microglia in vitro. | 2016 | Toxicol. Sci. | pmid:26609141 |
Siewiera K et al. | Long-term untreated streptozotocin-diabetes leads to increased expression and elevated activity of prostaglandin H2 synthase in blood platelets. | 2016 | Platelets | pmid:26325148 |
Olszowski T et al. | The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages. | 2015 | Biol Trace Elem Res | pmid:25645360 |
Al-Husseini A et al. | Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. | 2015 | PLoS ONE | pmid:25785937 |
Mateu A et al. | Cross-talk between TLR4 and PPARγ pathways in the arachidonic acid-induced inflammatory response in pancreatic acini. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26510582 |
Sahota T et al. | Model-based prediction of the acute and long-term safety profile of naproxen in rats. | 2015 | Br. J. Pharmacol. | pmid:25884765 |
Violi F et al. | Reply: platelet activation and pneumonia: is soluble p-selectin the right marker? | 2015 | J. Am. Coll. Cardiol. | pmid:25857924 |
Gurbel PA et al. | Platelet activation and pneumonia: is soluble p-selectin the right marker? | 2015 | J. Am. Coll. Cardiol. | pmid:25857923 |
Violi F et al. | Reply: myocardial infarction in patients with pneumonia. | 2015 | J. Am. Coll. Cardiol. | pmid:25857922 |
Savas G and Kalay N | Myocardial infarction in patients with pneumonia. | 2015 | J. Am. Coll. Cardiol. | pmid:25857921 |
Santos-Gallego CG and Badimon J | Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? | 2015 | J. Am. Coll. Cardiol. | pmid:25857920 |
Violi F et al. | Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? | 2015 | J. Am. Coll. Cardiol. | pmid:25857919 |
Khan AR et al. | Platelet activation and myocardial infarction in patients with pneumonia: are statins the answer? | 2015 | J. Am. Coll. Cardiol. | pmid:25857918 |
Gavriilaki E et al. | Platelets interplay between pneumonia and cardiovascular events: establishing a link? | 2015 | J. Am. Coll. Cardiol. | pmid:25857917 |
Véricel E et al. | Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. | 2015 | Thromb. Haemost. | pmid:25832443 |
Khanna V et al. | Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? | 2015 | J. Thromb. Haemost. | pmid:25809653 |
Wu F et al. | Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension. | 2015 | Chin. Med. J. | pmid:25591555 |
Karamouzis I et al. | Enhanced oxidative stress and platelet activation in patients with Cushing's syndrome. | 2015 | Clin. Endocrinol. (Oxf) | pmid:24923553 |