Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Menorrhagia D008595 4 associated lipids
Thrombasthenia D013915 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Sirois P et al. Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1 alpha thromboxane B2 and histamine on selected smooth muscle preparations. 1981 J. Pharm. Pharmacol. pmid:6115037
Hales CA et al. Role of thromboxane and prostacyclin in pulmonary vasomotor changes after endotoxin in dogs. 1981 J. Clin. Invest. pmid:7021593
Hyman AL et al. Prostaglandins and the lung. 1981 Med. Clin. North Am. pmid:7024664
Rosenfeld J et al. Extractive alkylation of prostaglandins. 1981 Prostaglandins pmid:7010456
Ylikorkala O et al. Effect of cytostatics on prostaglandin F2 alpha prostacyclin, and thromboxane in patients with gynecologic malignancies. 1981 Obstet Gynecol pmid:7024882
Tanaka M et al. Increased prostacyclin synthesizing activity in human ripening uterine cervix. 1981 Prostaglandins pmid:7010458
Siess W et al. Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation. 1981 Thromb. Haemost. pmid:7025338
Gonzalez-Crussi F et al. Prostaglandins in histiocytosis-X. PG synthesis by histiocytosis-X cells. 1981 Am. J. Clin. Pathol. pmid:6970520
Araki H et al. Mechanism of protection against arachidonate induced sudden death by glucocorticoid. 1981 Prostaglandins pmid:7232764
Roselló J et al. Quantitative profiling of the metabolic cascade of arachidonic acid by capillary gas chromatography mass spectrometry. 1981 Biomed. Mass Spectrom. pmid:7236862
Tyler HM et al. Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. 1981 Lancet pmid:6110861
Vermylen J et al. Thromboxane synthetase inhibition as antithrombotic strategy. 1981 Lancet pmid:6112447
Feuerstein N et al. 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. 1981 J. Pharm. Pharmacol. pmid:6115021
Foegh ML et al. Urine i-TXB2 in renal allograft rejection. 1981 Lancet pmid:6115199
Utsunomiya T et al. Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). 1981 Ann. Surg. pmid:6117260
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Kelly KL and Laychock SG Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. 1981 Prostaglandins pmid:6803305
Lagarde M et al. Inhibition of thrombin-induced platelet arachidonic acid release by 15-hydroperoxy-arachidonic acid. 1981 Biochem. Biophys. Res. Commun. pmid:7259783
Livio M et al. Differential effects of itanoxone--a new hypolipidemic and hypouricemic drug--on platelet and vascular prostaglandin generation in rats. 1981 Atherosclerosis pmid:7259827
Sterin-Borda L et al. Stimulating effect of thromboxane B2 on isolated rat atria. 1981 Experientia pmid:7262286
Roberts LJ et al. Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. 1981 J. Biol. Chem. pmid:7263660
Zijlstra FJ and Vincent JE Contractile characteristics of the rat stomach strip and the rabbit aorta and mesenteric artery. 1981 J Pharmacol Methods pmid:7265989
Hirsh PD et al. Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. 1981 N. Engl. J. Med. pmid:6894016
Allan G and Levi R Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro. 1981 J. Pharmacol. Exp. Ther. pmid:6894166
Malemud CJ et al. Prostaglandin biosynthesis by lapine articular chondrocytes in culture. 1981 Biochim. Biophys. Acta pmid:6894251
Ohnishi H et al. Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2. 1981 Prostaglandins Med pmid:6894333
Sobel M et al. Circulating platelet products in unstable angina pectoris. 1981 Circulation pmid:6450001
Russell NH et al. Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. 1981 Thromb. Res. pmid:6794179
Mezzano D et al. Evidence that platelet buoyant density, but not size, correlates with platelet age in man. 1981 Am. J. Hematol. pmid:7270546
Strano A et al. Thromboxane formation by platelets and platelet sensitivity to prostacyclin in patients with acute myocardial infarction. 1981 Thromb. Haemost. pmid:7036402
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Spagnuolo PJ et al. Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. 1980 J. Clin. Invest. pmid:6772674
Best LC et al. The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. 1980 Thromb. Haemost. pmid:6773171
Olund A et al. Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. 1980 Prostaglandins pmid:6775353
Bisordi JE et al. Interaction of vasopressin and prostaglandins in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777397
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
Galli C et al. Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. 1980 Prog Food Nutr Sci pmid:6779348
Best LC et al. Studies on the role of calcium in the control of thromboxane B2 production. 1980 Artery pmid:6783015
Challis JR and Patrick JE The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. 1980 Semin. Perinatol. pmid:6992278
Ahnfelt-Rønne I et al. Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. 1980 Agents Actions pmid:6992544
Gullner HG et al. Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. 1980 Prostaglandins Med pmid:6994153
Patrono C et al. Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. 1980 Agents Actions Suppl. pmid:6787852
Brodie MJ et al. Is prostacyclin in the major pro-inflammatory prostanoid in joint fluid? 1980 Life Sci. pmid:6999274
Cella G et al. In vivo platelet release reaction in patients with heart valve prosthesis. 1980 Haemostasis pmid:6157609
Silver MJ et al. A model system for studying initial events in atherosclerosis. 1980 Artery pmid:7000044
Best LC et al. Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. 1980 Biochim. Biophys. Acta pmid:6251913
Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
Poyser NL and Scott FM Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. 1980 J. Reprod. Fertil. pmid:7001011
Lands WE et al. Recent concepts on platelet function and dietary lipids in coronary thrombosis, vasospasm and angina. 1980 Herz pmid:7007191
Subbiah MT et al. Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. 1980 Pharmacology pmid:7220591
Ali AE et al. Prostaglandin and thromboxane production by fibroblasts and vascular endothelial cells. 1980 Prostaglandins pmid:7008090
Ohtsu E and Matsuzawa T Metabolic alterations in the endogenous formation of 6 keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in the brain-stem of stroke-resistant spontaneously hypertensive rats. 1980 J. Nutr. Sci. Vitaminol. pmid:7229740
Vargaftig BB et al. Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. 1980 Eur. J. Pharmacol. pmid:7009169
Giri SN and Krishna GA Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. 1980 J Pharmacol Methods pmid:7009992
Mathé AA et al. Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. 1980 Lancet pmid:6101355
Mestel F et al. Severe bleeding associated with defective thromboxane synthetase. 1980 Lancet pmid:6101498
Pareti FI et al. Platelets and the vessel wall: how much aspirin? 1980 Lancet pmid:6101829
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Zahavi J et al. Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. 1980 Lancet pmid:6106784
Jécsai G and Bagdány S Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. 1980 Acta Biochim. Biophys. Acad. Sci. Hung. pmid:7282294
Hwang DH Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. 1980 Prostaglandins Med pmid:7413850
Cerskus AL et al. Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone. 1980 Thromb. Res. pmid:7414555
Tada M et al. Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease. 1980 Adv Myocardiol pmid:7423053
Matsumoto M et al. Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. 1980 Thromb. Haemost. pmid:7423441
Davies GC et al. Elevated plasma fibrinopeptide A and thromboxane B2 levels during cardiopulmonary bypass. 1980 Circulation pmid:6965618
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Galli C et al. Modulation of prostaglandin production in tissues by dietary essential fatty acids. 1980 Acta Med. Scand. Suppl. pmid:6935943
Wong PY et al. The role of calmodulin in prostaglandin metabolism. 1980 Ann. N. Y. Acad. Sci. pmid:6940495
Galli C et al. Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. 1980 Pharmacol Res Commun pmid:7393988
Oka M and Manku MS Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. 1980 Prostaglandins Med pmid:7394062
Karmali RA et al. Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. 1980 Prostaglandins Med pmid:7394064
Cooper JD et al. Prostaglandin production associated with the pulmonary vascular response to complement activation. 1980 Surgery pmid:7394704
Dupont J et al. Effects of dietary essential fatty acid concentration upon prostanoid synthesis in rats. 1980 J. Nutr. pmid:7400858
Rao GH et al. Influence of epinephrine on the aggregation response of aspirin-treated platelets. 1980 Prostaglandins Med pmid:7403340
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Hassid A and Dunn MJ Microsomal prostaglandin biosynthesis of human kidney. 1980 J. Biol. Chem. pmid:7358683
Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Van Praag D and Farber SJ Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. 1980 Adv Prostaglandin Thromboxane Res pmid:7369029
Kot PA et al. Modification of the cardiovascular actions of prostaglandins by thromboxane B2. 1980 Adv Prostaglandin Thromboxane Res pmid:7369035
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lewy RI Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. 1980 Haemostasis pmid:7372200
Powell WS Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. 1980 Prostaglandins pmid:6258197
Cook JA et al. Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. 1980 J. Clin. Invest. pmid:7350199
Stuart MJ et al. Effect of cholesterol on production of thromboxane b2 by platelets in vitro. 1980 N. Engl. J. Med. pmid:7350406
Kent L et al. Differential response of articular chondrocyte populations to thromboxane B2 and analogs of prostaglandin cyclic endoperoxides. 1980 Prostaglandins pmid:7384546
Wise WC et al. Ibuprofen improves survival from endotoxic shock in the rat. 1980 J. Pharmacol. Exp. Ther. pmid:7452480
Subbiah MT et al. Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. 1980 Thromb. Haemost. pmid:7455983
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751
Lewy RI et al. Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. 1980 Circulation pmid:7371128
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618
Vanderhoek JY et al. 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. 1980 J. Biol. Chem. pmid:6771259
Ali M et al. Inhibition of human platelet cyclooxygenase by alpha-tocopherol. 1980 Prostaglandins Med pmid:6771778