Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Menorrhagia D008595 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mitchell MD et al. Possible role for prostacyclin in human parturition. 1978 Prostaglandins pmid:373020
Goldstein IM et al. Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. 1978 J. Exp. Med. pmid:702055
Anhut H et al. Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. 1978 Prostaglandins pmid:704912
Nelson NA et al. Synthesis of thromboxane B2 metabolites. 1978 Prostaglandins pmid:704927
Marion J and Wolfe LS Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. 1978 Prostaglandins pmid:704928
Kitchen EA et al. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. 1978 Prostaglandins pmid:704931
Sors H et al. Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. 1978 Prostaglandins pmid:704933
Turk J et al. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. 1978 Prostaglandins pmid:704934
Raz A and Aharony D Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. 1978 Res. Commun. Chem. Pathol. Pharmacol. pmid:705027
Chang WC et al. Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. 1978 Biochem. Pharmacol. pmid:619892
Goetzl EJ and Gorman RR Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). 1978 J. Immunol. pmid:621391
Agradi E et al. Influence of short term dietary supplementation of different lipids on aggregation and arachidonic acid metabolism in rabbit platelets. 1978 Prostaglandins pmid:748984
Fitzpatrick FA and Gorman RR A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. 1978 Biochim. Biophys. Acta pmid:629996
Malik KU Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. 1978 Circ. Res. pmid:27321
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
Boura AL and Murphy RD Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. 1978 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:699382
Lefer AM et al. Protective effects of a novel thromboxane analog in lethal traumatic shock. 1979 Prostaglandins Med pmid:552102
Kanzaki Y et al. Thromboxane as possible trigger of liver regeneration. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:535003
Lewy RI et al. Comparison of plasma concentrations of thromboxane B2 in Prinzmetal's variant angina and classical angina pectoris. 1979 Clin Cardiol pmid:544110
Best LC et al. Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. 1979 Biochem. Biophys. Res. Commun. pmid:117802