Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Raynaud Disease D011928 7 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Respiration Disorders D012120 5 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Retinal Diseases D012164 4 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Rhinitis D012220 10 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Sclerosis D012598 5 associated lipids
Seizures D012640 87 associated lipids
Shock D012769 11 associated lipids
Shock, Septic D012772 11 associated lipids
Sneezing D012912 6 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Ulcer D013276 75 associated lipids
Stomach Volvulus D013277 1 associated lipids
Streptococcal Infections D013290 4 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Thrombasthenia D013915 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thromboembolism D013923 6 associated lipids
Thrombosis D013927 49 associated lipids
Tooth, Impacted D014095 9 associated lipids
Ulcer D014456 16 associated lipids
Uremia D014511 33 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Uveitis D014605 14 associated lipids
Varicose Veins D014648 7 associated lipids
Vascular Diseases D014652 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Weil Disease D014895 2 associated lipids
Wounds and Injuries D014947 20 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Reperfusion Injury D015427 65 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Meyers KM et al. A dominant role of thromboxane formation in secondary aggregation of platelets. 1979 Nature pmid:503210
de Deckere EA et al. Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. 1979 Prostaglandins pmid:504696
Powell WS Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. 1979 Biochim. Biophys. Acta pmid:518891
Spagnuolo C et al. Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. 1979 Prostaglandins pmid:523683
Bennett A and Sanger GJ Trimethoquinol selectively antagonises longitudinal muscle contractions of rat isolated gastric fundus to thromboxane B2 and epoxymethano analogues of PGH2 [proceedings]. 1979 Br. J. Pharmacol. pmid:526738
Prancan AV et al. L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. 1979 Eur. J. Pharmacol. pmid:527664
Makheja AN et al. Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. 1979 Prostaglandins Med pmid:552092
Lefer AM et al. Protective effects of a novel thromboxane analog in lethal traumatic shock. 1979 Prostaglandins Med pmid:552102
Daniel EE et al. Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. 1979 Prostaglandins pmid:379920
Kanzaki Y et al. Thromboxane as possible trigger of liver regeneration. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:535003
Russell FA and Deykin D The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. 1979 Prostaglandins pmid:523671
Kelly JP et al. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. 1979 J. Immunol. pmid:109510
Whittle BJ Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. 1979 Acta Obstet Gynecol Scand Suppl pmid:111464
Robinson JS et al. Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. 1979 J. Endocrinol. pmid:112214
Burch RM et al. Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. 1979 J. Pharmacol. Exp. Ther. pmid:113526
Patrono C et al. Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. 1979 Agents Actions Suppl. pmid:115255
Wong PY and Cheung WY Calmodulin stimulates human platelet phospholipase A2. 1979 Biochem. Biophys. Res. Commun. pmid:116656
Okuma M and Uchino H Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. 1979 Blood pmid:116695
Best LC et al. Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. 1979 Biochem. Biophys. Res. Commun. pmid:117802
Kass MA and Holmberg NJ Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. 1979 Invest. Ophthalmol. Vis. Sci. pmid:761971