Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jarvis GE et al. | A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). | 2012 | J. Thromb. Haemost. | pmid:22103309 |
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Hui C et al. | Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases. | 2012 | Arch. Gynecol. Obstet. | pmid:22083312 |
Wang Z et al. | Aspirin resistance in off-pump coronary artery bypass grafting. | 2012 | Eur J Cardiothorac Surg | pmid:21636287 |
Li C et al. | Reversal of the anti-platelet effects of aspirin and clopidogrel. | 2012 | J. Thromb. Haemost. | pmid:22268852 |
RodrÃguez-Vilarrupla A et al. | PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. | 2012 | J. Hepatol. | pmid:22245887 |
Mullins KB et al. | Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. | 2012 | Vet Anaesth Analg | pmid:22248445 |
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Lee JJ et al. | Morusinol extracted from Morus alba inhibits arterial thrombosis and modulates platelet activation for the treatment of cardiovascular disease. | 2012 | J. Atheroscler. Thromb. | pmid:22472211 |
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Totani L et al. | Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. | 2012 | Thromb. Haemost. | pmid:22436970 |
Ajamieh H et al. | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | J. Gastroenterol. Hepatol. | pmid:22432744 |
Shatoor AS et al. | Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats. | 2012 | Thromb. Res. | pmid:22261477 |
Brentnall C et al. | Potency and selectivity of carprofen enantiomers for inhibition of bovine cyclooxygenase in whole blood assays. | 2012 | Res. Vet. Sci. | pmid:22703724 |
Salama MM et al. | Resistance to low-dose aspirin therapy among patients with acute coronary syndrome in relation to associated risk factors. | 2012 | J Clin Pharm Ther | pmid:23121257 |
Yokoyama H et al. | Theoretical investigation of aspirin dosage regimen to exhibit optimal antiplatelet effects and decrease risk of upper gastrointestinal lesions. | 2012 | Biol. Pharm. Bull. | pmid:23047244 |
Liou JT et al. | Levobupivacaine differentially suppresses platelet aggregation by modulating calcium release in a dose-dependent manner. | 2012 | Acta Anaesthesiol Taiwan | pmid:23026170 |
Thomason J et al. | Platelet cyclooxygenase expression in normal dogs. | 2011 Sep-Oct | J. Vet. Intern. Med. | pmid:21985141 |
Alcott CJ et al. | Clinical and immunomodulating effects of ketamine in horses with experimental endotoxemia. | 2011 Jul-Aug | J. Vet. Intern. Med. | pmid:21745244 |
Chakroun T et al. | The cyclooxygenase-1 C50T polymorphism is not associated with aspirin responsiveness status in stable coronary artery disease in Tunisian patients. | 2011 Jul-Aug | Genet Test Mol Biomarkers | pmid:21434767 |