Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Raynaud Disease D011928 7 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Respiration Disorders D012120 5 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Retinal Diseases D012164 4 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Rhinitis D012220 10 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Sclerosis D012598 5 associated lipids
Seizures D012640 87 associated lipids
Shock D012769 11 associated lipids
Shock, Septic D012772 11 associated lipids
Sneezing D012912 6 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Ulcer D013276 75 associated lipids
Stomach Volvulus D013277 1 associated lipids
Streptococcal Infections D013290 4 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Thrombasthenia D013915 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thromboembolism D013923 6 associated lipids
Thrombosis D013927 49 associated lipids
Tooth, Impacted D014095 9 associated lipids
Ulcer D014456 16 associated lipids
Uremia D014511 33 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Uveitis D014605 14 associated lipids
Varicose Veins D014648 7 associated lipids
Vascular Diseases D014652 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Weil Disease D014895 2 associated lipids
Wounds and Injuries D014947 20 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Reperfusion Injury D015427 65 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Säynävälammi P Effects of captopril on the urinary excretion of prostanoids and kallikrein in spontaneously hypertensive rats. 1986 Acta Pharmacol Toxicol (Copenh) pmid:3541494
Khan HH et al. Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. 2000 Acta Pharmacol. Sin. pmid:11501061
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
Wang YY et al. Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. 2004 Acta Pharmacol. Sin. pmid:15066215
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Peng LL et al. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. 2016 Acta Pharmacol. Sin. pmid:27641736
Kapui Z et al. The mechanism of cytoprotective effect of CHINOIN-127. 1992 Acta Physiol Hung pmid:1345193
Nagy S et al. A canine model of hyperdynamic sepsis induced by intestinal ischemia. 1990 Acta Physiol Hung pmid:2075825
Nádasy GL et al. Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. 1991 Acta Physiol Hung pmid:1763652
Somova L et al. Pathogenesis of cardiovascular disorders in streptozotocin-induced diabetes in rat. II. Correlation between lipid peroxides, thromboxane A2/prostacyclin, and platelet aggregation in different stages of diabetes. 1988 Acta Physiol Pharmacol Bulg pmid:3066112