Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yamamoto T et al. | Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198239 |
Kay-Mugford T and Conlon P | Possible inconsistencies in study on cyclooxygenase. | 1999 | Am. J. Vet. Res. | pmid:10188806 |
Mayer AM et al. | Escherichia coli lipopolysaccharide potentiation and inhibition of rat neonatal microglia superoxide anion generation: correlation with prior lactic dehydrogenase, nitric oxide, tumor necrosis factor-alpha, thromboxane B2, and metalloprotease release. | 1999 | Shock | pmid:10188770 |
Mitchell MD et al. | Production of thromboxane B2 by the intra-uterine tissues from late pregnant Rhesus monkeys (Macaca mulatta) in vitro. | 1978 | J. Endocrinol. | pmid:101641 |
Stenach N et al. | The effects of heparin bound surface modification (Carmeda Bioactive Surface) on human platelet alterations during simulated extracorporeal circulation. | 1992 | J Extra Corpor Technol | pmid:10148074 |
Takami M and Tsukada W | Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10102387 |
Hu MK et al. | Synthesis and evaluation of backbone/amide-modified analogs of leualacin. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10098664 |
van Genderen PJ et al. | Thromboxane-dependent platelet activation in vivo precedes arterial thrombosis in thrombocythaemia: a rationale for the use of low-dose aspirin as an antithrombotic agent. | 1999 | Br. J. Haematol. | pmid:10086775 |
van den Dorpel MA et al. | Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083130 |
Pestana M et al. | Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083119 |
Yi Z et al. | [Changes and evaluation of indexes on treating ganyanghuafengzheng with cerebral infarction by tianlongxifeng granulae]. | 1997 | Hunan Yi Ke Da Xue Xue Bao | pmid:10073023 |
Li W et al. | [Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension]. | 1997 | Hunan Yi Ke Da Xue Xue Bao | pmid:10072988 |
Zeng S and Guo ZG | Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072970 |
Shen ZQ et al. | Inhibitory effects of copper-aspirin complex on platelet aggregation. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072923 |
Takahashi H et al. | Ureteral obstruction reverses glomerular proliferation in immune complex glomerulonephritis. | 1999 | J. Lab. Clin. Med. | pmid:10072261 |
Fukushima C et al. | In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients. | 1999 | Ann. Allergy Asthma Immunol. | pmid:10071522 |
Mink SN et al. | Effect of bolus epinephrine on systemic hemodynamics in canine anaphylactic shock. | 1998 | Cardiovasc. Res. | pmid:10070496 |
Langberg H et al. | Metabolism and inflammatory mediators in the peritendinous space measured by microdialysis during intermittent isometric exercise in humans. | 1999 | J. Physiol. (Lond.) | pmid:10066916 |
van Kooten F et al. | Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage. | 1999 | Stroke | pmid:10066850 |
Jokela R et al. | Effect of in vitro stability of dietary fish oil on lipid peroxidation and prostanoids in vivo. | 1998 | Ups. J. Med. Sci. | pmid:10052110 |