Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Femoral Fractures D005264 7 associated lipids
Fatty Liver D005234 48 associated lipids
Facial Pain D005157 5 associated lipids
Eye Burns D005126 13 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Erythromelalgia D004916 1 associated lipids
Enteritis D004751 8 associated lipids
Endometriosis D004715 29 associated lipids
Embolism, Fat D004620 4 associated lipids
Edema, Cardiac D004489 1 associated lipids
Edema D004487 152 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Drowning D004332 2 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Diseases in Twins D004200 4 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Death, Sudden D003645 12 associated lipids
Cough D003371 19 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Coronary Disease D003327 70 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Contusions D003288 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colitis D003092 69 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Chest Pain D002637 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Celiac Disease D002446 16 associated lipids
Cattle Diseases D002418 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Byssinosis D002095 11 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kowalska MA et al. Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. 2000 Blood pmid:10891429
Bailey SR et al. Differential activation of platelets from normal and allergic ponies by PAF and ADP. 2000 Inflamm. Res. pmid:10893045
Rao AR and Prabhakar MC Screening methods for antiasthmatic agents. 2000 Methods Find Exp Clin Pharmacol pmid:10893704
Cayatte AJ et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10894809
Sugimoto KI et al. Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. 2000 Clin. Exp. Pharmacol. Physiol. pmid:10901388
Köfeler HC et al. Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. 2000 Br. J. Pharmacol. pmid:10903961
Toft G et al. Intravenously and topically applied magnesium in the prevention of arterial thrombosis. 2000 Thromb. Res. pmid:10904104
Giedrojć J et al. [Investigation of prostaglandins in supernatant of cultured monocytes]. 2000 Prz. Lek. pmid:10907365
Momi S et al. Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. 2000 Exp. Parasitol. pmid:10910715
Ogura Y et al. Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). 2000 Carcinogenesis pmid:10910946
MalatyalioÄŸlu E et al. Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. 2000 May-Jun J Matern Fetal Med pmid:10914626
Patrignani P et al. Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. 2000 Circulation pmid:10920066
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Wang JS et al. Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. 2000 Thromb. Haemost. pmid:10928481
Kamata K et al. Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. 2000 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10935533
Kim WG et al. Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. 2000 Int J Artif Organs pmid:10941636
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Porta C et al. Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. 2000 Haematologica pmid:10942928
Sane S et al. Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. 2000 J. Surg. Res. pmid:10945939