Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Femoral Fractures D005264 7 associated lipids
Fatty Liver D005234 48 associated lipids
Facial Pain D005157 5 associated lipids
Eye Burns D005126 13 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Erythromelalgia D004916 1 associated lipids
Enteritis D004751 8 associated lipids
Endometriosis D004715 29 associated lipids
Embolism, Fat D004620 4 associated lipids
Edema, Cardiac D004489 1 associated lipids
Edema D004487 152 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Drowning D004332 2 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Diseases in Twins D004200 4 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Death, Sudden D003645 12 associated lipids
Cough D003371 19 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Coronary Disease D003327 70 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Contusions D003288 3 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colitis D003092 69 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Chest Pain D002637 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Celiac Disease D002446 16 associated lipids
Cattle Diseases D002418 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Byssinosis D002095 11 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Säynävälammi P Effects of captopril on the urinary excretion of prostanoids and kallikrein in spontaneously hypertensive rats. 1986 Acta Pharmacol Toxicol (Copenh) pmid:3541494
Khan HH et al. Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. 2000 Acta Pharmacol. Sin. pmid:11501061
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
Wang YY et al. Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. 2004 Acta Pharmacol. Sin. pmid:15066215
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Peng LL et al. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. 2016 Acta Pharmacol. Sin. pmid:27641736
Kapui Z et al. The mechanism of cytoprotective effect of CHINOIN-127. 1992 Acta Physiol Hung pmid:1345193
Nagy S et al. A canine model of hyperdynamic sepsis induced by intestinal ischemia. 1990 Acta Physiol Hung pmid:2075825
Nádasy GL et al. Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. 1991 Acta Physiol Hung pmid:1763652
Somova L et al. Pathogenesis of cardiovascular disorders in streptozotocin-induced diabetes in rat. II. Correlation between lipid peroxides, thromboxane A2/prostacyclin, and platelet aggregation in different stages of diabetes. 1988 Acta Physiol Pharmacol Bulg pmid:3066112