Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sanger GJ and Bennett A | Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6103666 |
Lindgren JA et al. | Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247886 |
Gorman RR | Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247892 |
Harris RH et al. | Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6768234 |
Schlondorff D and Folkert VW | Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369028 |
Langs DA et al. | Thromboxane molecules are not hairpin conformers. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386281 |
Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
Flynn JT and Demling RH | Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. | 1982 | Adv Shock Res | pmid:6753534 |
Lefer AM and Crossley K | Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. | 1980 | Adv Shock Res | pmid:7304314 |
Hadding U et al. | Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. | 1982 | Adv. Exp. Med. Biol. | pmid:7158499 |