Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Nørregaard R et al. | Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20147610 |
Carroll RC et al. | Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance. | 2010 | Thromb. Res. | pmid:19962724 |
Dragani A et al. | Clinical and laboratory phenotype associated with the aspirin-like defect. | 2010 | Br. J. Haematol. | pmid:19814736 |
Maddens BE et al. | Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. | 2010 | Vet. Immunol. Immunopathol. | pmid:19815297 |
King JN et al. | In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. | 2010 | Res. Vet. Sci. | pmid:20004922 |
Zisman E et al. | Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients. | 2010 | Eur J Anaesthesiol | pmid:20035230 |
Oldenhof J et al. | Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. | 2010 | Curr Med Res Opin | pmid:20429831 |
Qu C et al. | Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20444882 |
Renda G et al. | Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance. | 2010 | Haematologica | pmid:21123440 |
Iagoda AV and Gladkikh NN | [Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities]. | 2010 | Ter. Arkh. | pmid:21086621 |
Warner JH et al. | Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. | 2010 | BMC Med Res Methodol | pmid:20233412 |
Bollinger JG et al. | Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization. | 2010 | Anal. Chem. | pmid:20704368 |
Antonino MJ et al. | Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone. | 2010 | Thromb. Res. | pmid:19446864 |
Iwasaki W et al. | Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. | 2010 | Shock | pmid:19543146 |
Dołegowska B et al. | Dynamics of thromboxane level changes during early phase of allograft reperfusion. | 2009 Sep-Oct | Clin Transplant | pmid:19298388 |
Tantry US et al. | Aspirin resistance. | 2009 Sep-Oct | Prog Cardiovasc Dis | pmid:19732606 |
Thomson VS et al. | Aspirin resistance in Indian patients with coronary artery disease and cardiovascular events. | 2009 Oct-Dec | J Postgrad Med | pmid:20083870 |
Goodman L et al. | Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model. | 2009 Jan-Feb | J. Vet. Intern. Med. | pmid:19175721 |
Capodanno D and Angiolillo DJ | Platelet monitoring for PCI: which test is the one to choose? | 2009 | Hamostaseologie | pmid:19882078 |
Li M et al. | Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. | 2009 | J. Vasc. Res. | pmid:19571576 |
McClelland S et al. | Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. | 2009 | Atherosclerosis | pmid:18514659 |
Huntjens DR et al. | Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. | 2009 | Eur J Pain | pmid:18774319 |
Xu Y et al. | Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19572944 |
Zhao L et al. | Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. | 2009 | Br. J. Pharmacol. | pmid:19220291 |
Shah KB et al. | The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. | 2009 | Hypertension | pmid:19597033 |
Ulbrich SE et al. | Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. | 2009 | Reproduction | pmid:19470711 |
Kanazawa S et al. | Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. | 2009 | Platelets | pmid:19172526 |
Calapai G et al. | Cardiovascular biomarkers in groups of established smokers after a decade of smoking. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19175368 |
Kapetanovic IM et al. | Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. | 2009 | Chem. Biol. Interact. | pmid:18992230 |
Seta F et al. | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19357295 |
Pettinella C et al. | Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. | 2009 | Thromb. Haemost. | pmid:19350112 |
Basselin M et al. | Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. | 2009 | Neuropsychopharmacology | pmid:19145225 |
Guagnano MT et al. | Determinants of platelet activation in hypertensives with microalbuminuria. | 2009 | Free Radic. Biol. Med. | pmid:19280705 |
Lo HM et al. | 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | 2009 | Pharmacology | pmid:19690443 |
Struthmann L et al. | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. | 2009 | J. Thromb. Haemost. | pmid:19691487 |
Omura Y et al. | Severe asthma with markedly increased asbestos of 2 types & TXB2, and markedly reduced acetylcholine, DHEA & drug uptake in parts of upper lungs, & similar abnormalities at respiratory & cardiac center of medulla oblongata: complete elimination of this asthma within 15 days using one optimal dose of astragalus & application of strong red light & EMF neutralizer on respiratory centers of abnormal medulla oblongata. | 2009 | Acupunct Electrother Res | pmid:19711774 |
Sobotková A et al. | Antioxidants change platelet responses to various stimulating events. | 2009 | Free Radic. Biol. Med. | pmid:19766712 |
Shen H et al. | Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). | 2009 | Am. J. Cardiol. | pmid:19660620 |
Leoncini G et al. | In retinal vein occlusion platelet response to thrombin is increased. | 2009 | Thromb. Res. | pmid:19660790 |
Canales A et al. | Platelet aggregation, eicosanoid production and thrombogenic ratio in individuals at high cardiovascular risk consuming meat enriched in walnut paste. A crossover, placebo-controlled study. | 2009 | Br. J. Nutr. | pmid:19068151 |
Lauring B et al. | Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. | 2009 | J Clin Pharmacol | pmid:19833861 |
Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
Cattaneo M | Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". | 2009 | Circulation | pmid:19546394 |
Schiff M et al. | Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. | 2009 | Curr Med Res Opin | pmid:19678751 |
Cook VL et al. | Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. | 2009 | Am. J. Vet. Res. | pmid:19645580 |
Blais N et al. | Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). | 2009 | Thromb. Haemost. | pmid:19652893 |
Zhang X et al. | Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. | 2009 | Pancreas | pmid:19657312 |
Liu FC et al. | A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. | 2009 | Biochem. Pharmacol. | pmid:19426675 |
Peng CY et al. | Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19429858 |
Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |