Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Ventricular Dysfunction, Left D018487 33 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Hypertension, Portal D006975 12 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Sclerosis D012598 5 associated lipids
Atherosclerosis D050197 85 associated lipids
beta-Thalassemia D017086 5 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Coronary Stenosis D023921 6 associated lipids
Bacteremia D016470 9 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Menorrhagia D008595 4 associated lipids
Dyslipidemias D050171 7 associated lipids
Pregnancy Complications D011248 19 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Cat Diseases D002371 12 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Weight Loss D015431 56 associated lipids
Endotoxemia D019446 27 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Lupus Nephritis D008181 8 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Obesity, Morbid D009767 8 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Weil Disease D014895 2 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Sneezing D012912 6 associated lipids
Helicobacter Infections D016481 21 associated lipids
Infertility D007246 3 associated lipids
Embolism, Fat D004620 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Heart Septal Defects D006343 2 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Hydatidiform Mole D006828 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Lumley P et al. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825385
Patrono C et al. Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825389
Zhao Y et al. Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825392
Vial JH et al. Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825534
Ritter JM et al. On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825568
Fuse I and Tai HH Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526540
Houtz P and Tai HH Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526560
Hayashi Y et al. Radioimmunoassay of 11-dehydro-thromboxane B2 using monoclonal antibody. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526561
Knospe J et al. Derivatization of prostaglandins to corresponding anilides and analysis by HPLC. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526562
De Caterina R et al. Characteristics of thromboxane production by the isolated-perfused rat heart. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959082
Samhoun MN et al. Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960144
Granström E and Kumlin M Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960161
Lecompte T et al. Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960162
Catella F et al. Analysis of multiple thromboxane metabolites in plasma and urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960166
Alessandrini P et al. Eicosanoid biosynthesis in human diabetes mellitus. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960175
Nihei C et al. Clinical study on effect of thromboxane A2 synthetase inhibitor (OKY-046) to clarify the regulation of cerebral blood flow in cerebral thrombosis. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960210
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936139
Kobayashi N et al. Effect of changes in prostaglandin synthesis by platelets and vessel wall on the formation of arterial thrombosis in rabbits. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936159
Nishikawa K et al. (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid (CV-4151): a potent, specific thromboxane A2 synthetase inhibitor. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936160
Takagi S and Den K Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936183