Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Ventricular Dysfunction, Left D018487 33 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Hypertension, Portal D006975 12 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Sclerosis D012598 5 associated lipids
Atherosclerosis D050197 85 associated lipids
beta-Thalassemia D017086 5 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Coronary Stenosis D023921 6 associated lipids
Bacteremia D016470 9 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Menorrhagia D008595 4 associated lipids
Dyslipidemias D050171 7 associated lipids
Pregnancy Complications D011248 19 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Cat Diseases D002371 12 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Weight Loss D015431 56 associated lipids
Endotoxemia D019446 27 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Lupus Nephritis D008181 8 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Obesity, Morbid D009767 8 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Weil Disease D014895 2 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Sneezing D012912 6 associated lipids
Helicobacter Infections D016481 21 associated lipids
Infertility D007246 3 associated lipids
Embolism, Fat D004620 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Heart Septal Defects D006343 2 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Hydatidiform Mole D006828 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Säynävälammi P Effects of captopril on the urinary excretion of prostanoids and kallikrein in spontaneously hypertensive rats. 1986 Acta Pharmacol Toxicol (Copenh) pmid:3541494
Khan HH et al. Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. 2000 Acta Pharmacol. Sin. pmid:11501061
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
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Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Peng LL et al. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. 2016 Acta Pharmacol. Sin. pmid:27641736
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Nagy S et al. A canine model of hyperdynamic sepsis induced by intestinal ischemia. 1990 Acta Physiol Hung pmid:2075825
Nádasy GL et al. Role of endothelium, oxygen and ionic milieu in the prostacyclin and thromboxane production of rat aortic tissue slices. 1991 Acta Physiol Hung pmid:1763652
Somova L et al. Pathogenesis of cardiovascular disorders in streptozotocin-induced diabetes in rat. II. Correlation between lipid peroxides, thromboxane A2/prostacyclin, and platelet aggregation in different stages of diabetes. 1988 Acta Physiol Pharmacol Bulg pmid:3066112