Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Langs DA et al. | Thromboxane molecules do not adopt the prostaglandin hairpin conformation. | 1979 | Nature | pmid:481594 |
Jonsson CE et al. | Prostaglandins and thromboxanes in burn injury in man. | 1979 | Scand J Plast Reconstr Surg | pmid:451477 |
Bailey JM et al. | Anti-inflammatory drugs in experimental atherosclerosis. Part 4. Inhibition of atherosclerosis in vivo and thromboxane synthesis and platelet aggregation in vitro. | 1979 | Atherosclerosis | pmid:454516 |
Taylor L et al. | Prostaglandin production by type II alveolar epithelial cells. | 1979 | Biochim. Biophys. Acta | pmid:435506 |
Folkert VW and Schlondorff D | Prostaglandin synthesis in isolated glomeruli. | 1979 | Prostaglandins | pmid:441427 |
Parker CW et al. | Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. | 1979 | J. Immunol. | pmid:448099 |
Needleman P et al. | Platelet and blood vessel arachidonate metabolism and interactions. | 1979 | J. Clin. Invest. | pmid:372240 |
Morley J et al. | Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. | 1979 | Prostaglandins | pmid:493559 |
Meyers KM et al. | A dominant role of thromboxane formation in secondary aggregation of platelets. | 1979 | Nature | pmid:503210 |
de Deckere EA et al. | Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. | 1979 | Prostaglandins | pmid:504696 |
Powell WS | Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. | 1979 | Biochim. Biophys. Acta | pmid:518891 |
Lewy RI et al. | Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina. | 1979 | Prostaglandins Med | pmid:575861 |
Ohuchi K et al. | Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma. | 1979 | Prostaglandins Med | pmid:583576 |
Roberts LJ et al. | Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. | 1979 | Biochim. Biophys. Acta | pmid:389290 |
Dutilh CE et al. | Study of the two pathways for arachidonate oxygenation in blood platelets. | 1979 | Lipids | pmid:34075 |
Kelly JP et al. | Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. | 1979 | J. Immunol. | pmid:109510 |
Whittle BJ | Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. | 1979 | Acta Obstet Gynecol Scand Suppl | pmid:111464 |
Robinson JS et al. | Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. | 1979 | J. Endocrinol. | pmid:112214 |
Dembińska-Kièć A et al. | Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. | 1979 | Atherosclerosis | pmid:224890 |
Peskar BA and Holland A | Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. | 1979 | Agents Actions Suppl. | pmid:294148 |