Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Spagnuolo PJ et al. | Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. | 1980 | J. Clin. Invest. | pmid:6772674 |
| Best LC et al. | The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. | 1980 | Thromb. Haemost. | pmid:6773171 |
| Stuart MJ et al. | The influence of albumin and calcium on human platelet arachidonic acid metabolism. | 1980 | Blood | pmid:6766753 |
| Challis JR and Patrick JE | The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. | 1980 | Semin. Perinatol. | pmid:6992278 |
| Ahnfelt-Rønne I et al. | Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. | 1980 | Agents Actions | pmid:6992544 |
| Crutchley DJ et al. | Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. | 1980 | Am. Rev. Respir. Dis. | pmid:6155814 |
| Cella G et al. | In vivo platelet release reaction in patients with heart valve prosthesis. | 1980 | Haemostasis | pmid:6157609 |
| Best LC et al. | Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. | 1980 | Biochim. Biophys. Acta | pmid:6251913 |
| Zapol WM et al. | Plasma thromboxane and prostacyclin metabolites in sheep partial cardiopulmonary bypass. | 1980 | Trans Am Soc Artif Intern Organs | pmid:7018060 |
| Güllner HG et al. | Correction of increased prostacyclin production in Bartter's syndrome by indomethacin. | 1980 | Trans. Assoc. Am. Physicians | pmid:7018063 |
| Salmon JA | Analysis of arachidonic acid metabolites by radioimmunoassay and physicochemical methods. | 1980 | Mater Med Pol | pmid:7019588 |
| Zamecnik J et al. | Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6990719 |
| Frame MH et al. | Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6990724 |
| Güllner HG et al. | The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6892749 |
| Liggins GC et al. | Production rates of prostaglandin F, 6-keto-PGF1 alpha and thromboxane B2 by perifused human endometrium. | 1980 | Prostaglandins | pmid:6892962 |
| Subbiah MT and Dietemeyer D | Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats. | 1980 | Biochem Med | pmid:6893150 |
| Ali M and McDonald JW | Synthesis of thromboxane B2 and 6-keto-prostaglandin F1 alpha by bovine gastric mucosal and muscle microsomes. | 1980 | Prostaglandins | pmid:6893365 |
| Ohuchi K et al. | Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. | 1980 | Prostaglandins Med | pmid:6893750 |
| Galli C et al. | Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. | 1980 | Pharmacol Res Commun | pmid:7393988 |
| Chiabrando C et al. | Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. | 1980 | Prostaglandins | pmid:6894036 |
| Oka M and Manku MS | Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. | 1980 | Prostaglandins Med | pmid:7394062 |
| Katori M et al. | Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377020 |
| Crutchley DJ et al. | Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377022 |
| Morris HG and Sherman NA | Prostaglandin-like substances in urine of asthmatic patients. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377024 |
| Schoene NW et al. | Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377026 |
| Smith EF et al. | Influence of thromboxane inhibition on the severity of myocardial ischemia in cats. | 1980 | Can. J. Physiol. Pharmacol. | pmid:7378931 |
| Ellwood DA et al. | Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. | 1980 | Prostaglandins | pmid:7384553 |
| Lagarde M et al. | Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. | 1980 | Prostaglandins | pmid:7384555 |
| Patrono C et al. | Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386257 |
| Langs DA et al. | Thromboxane molecules are not hairpin conformers. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386281 |
| Lefer AM et al. | Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6929517 |
| Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
| Moretti RL and Lin CY | Coronary vasoconstrictor extracted from blood plasma stimulates platelet lipoxidase activity. | 1980 | Prostaglandins | pmid:6770419 |
| Maggi FM et al. | Prostaglandin synthetase activity in vascular tissue of male and female rats. | 1980 | Prostaglandins | pmid:6770422 |
| Feinstein MB et al. | Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6770602 |
| Cook JA et al. | Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. | 1980 | J. Clin. Invest. | pmid:7350199 |
| Bolton HS et al. | Prostaglandin synthesis by adult heart myocytes. | 1980 | J. Mol. Cell. Cardiol. | pmid:7441771 |
| Dejana E et al. | Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats. | 1980 | Br. J. Haematol. | pmid:7448129 |
| Ylikorkala O and Viinikka L | Thromboxane A2 in pregnancy and puerperium. | 1980 | Br Med J | pmid:7448530 |
| Bone EA et al. | The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. | 1980 | Biochem. Soc. Trans. | pmid:7450206 |
| Mitchell MD | Prostaglandins at parturition and in the neonatal infant. | 1980 | Biochem. Soc. Trans. | pmid:7450282 |
| Best LC et al. | The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets. | 1980 | Clin. Sci. | pmid:7190885 |
| Heggers JP et al. | Histological demonstration of prostaglandins and thromboxanes in burned tissue. | 1980 | J. Surg. Res. | pmid:6987462 |
| Vanderhoek JY et al. | 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. | 1980 | J. Biol. Chem. | pmid:6771259 |
| Ali M et al. | Inhibition of human platelet cyclooxygenase by alpha-tocopherol. | 1980 | Prostaglandins Med | pmid:6771778 |
| Hagen AA et al. | Synthesis of prostaglandins and thromboxane B2 by cerebral arteries. | 1979 May-Jun | Stroke | pmid:462519 |
| Anhut H et al. | Thromboxane B2 release and 3H-noradrenaline accumulation by a synaptosomal fraction of rat brain. | 1979 Jul-Aug | Pol J Pharmacol Pharm | pmid:523340 |
| Pradalier A et al. | [Measurement of plasma and serum values of PGE2, PGF2 alpha and TXB2 during aspirin induced bronchospasm in asthmatics (author's transl)]. | 1979 Jul-Aug | Therapie | pmid:531778 |
| Mitchell MD et al. | Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. | 1979 | J. Reprod. Fertil. | pmid:423152 |
| Tobelem G et al. | Further studies on a specific platelet antibody found in Bernard-Soulier syndrome and its effects on normal platelet function. | 1979 | Br. J. Haematol. | pmid:427045 |
| Friedman LS et al. | Cardiovascular and pulmonary effects of thromboxane B2 in the dog. | 1979 | Circ. Res. | pmid:428069 |
| Ciabattoni G et al. | Characterization of furosemide-induced activation of the renal prostaglandin system. | 1979 | Eur. J. Pharmacol. | pmid:393525 |
| Jonsson CE et al. | Prostaglandins and thromboxanes in burn injury in man. | 1979 | Scand J Plast Reconstr Surg | pmid:451477 |
| Bailey JM et al. | Anti-inflammatory drugs in experimental atherosclerosis. Part 4. Inhibition of atherosclerosis in vivo and thromboxane synthesis and platelet aggregation in vitro. | 1979 | Atherosclerosis | pmid:454516 |
| Taylor L et al. | Prostaglandin production by type II alveolar epithelial cells. | 1979 | Biochim. Biophys. Acta | pmid:435506 |
| Folkert VW and Schlondorff D | Prostaglandin synthesis in isolated glomeruli. | 1979 | Prostaglandins | pmid:441427 |
| Parker CW et al. | Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. | 1979 | J. Immunol. | pmid:448099 |
| Needleman P et al. | Platelet and blood vessel arachidonate metabolism and interactions. | 1979 | J. Clin. Invest. | pmid:372240 |
| Morley J et al. | Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. | 1979 | Prostaglandins | pmid:493559 |
| Meyers KM et al. | A dominant role of thromboxane formation in secondary aggregation of platelets. | 1979 | Nature | pmid:503210 |
| de Deckere EA et al. | Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. | 1979 | Prostaglandins | pmid:504696 |
| Powell WS | Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. | 1979 | Biochim. Biophys. Acta | pmid:518891 |
| Spagnuolo C et al. | Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. | 1979 | Prostaglandins | pmid:523683 |
| Bennett A and Sanger GJ | Trimethoquinol selectively antagonises longitudinal muscle contractions of rat isolated gastric fundus to thromboxane B2 and epoxymethano analogues of PGH2 [proceedings]. | 1979 | Br. J. Pharmacol. | pmid:526738 |
| Prancan AV et al. | L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. | 1979 | Eur. J. Pharmacol. | pmid:527664 |
| Makheja AN et al. | Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. | 1979 | Prostaglandins Med | pmid:552092 |
| Lefer AM et al. | Protective effects of a novel thromboxane analog in lethal traumatic shock. | 1979 | Prostaglandins Med | pmid:552102 |
| Russell NH et al. | Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. | 1979 | Br. J. Haematol. | pmid:570847 |
| Daniel EE et al. | Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. | 1979 | Prostaglandins | pmid:379920 |
| Kanzaki Y et al. | Thromboxane as possible trigger of liver regeneration. | 1979 | Cell Mol Biol Incl Cyto Enzymol | pmid:535003 |
| Lewy RI et al. | Comparison of plasma concentrations of thromboxane B2 in Prinzmetal's variant angina and classical angina pectoris. | 1979 | Clin Cardiol | pmid:544110 |
| Russell FA and Deykin D | The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. | 1979 | Prostaglandins | pmid:523671 |
| Roberts LJ et al. | Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. | 1979 | Biochim. Biophys. Acta | pmid:389290 |
| Dutilh CE et al. | Study of the two pathways for arachidonate oxygenation in blood platelets. | 1979 | Lipids | pmid:34075 |
| Kelly JP et al. | Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. | 1979 | J. Immunol. | pmid:109510 |
| Whittle BJ | Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. | 1979 | Acta Obstet Gynecol Scand Suppl | pmid:111464 |
| Robinson JS et al. | Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. | 1979 | J. Endocrinol. | pmid:112214 |
| Burch RM et al. | Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. | 1979 | J. Pharmacol. Exp. Ther. | pmid:113526 |
| Patrono C et al. | Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. | 1979 | Agents Actions Suppl. | pmid:115255 |
| Wong PY and Cheung WY | Calmodulin stimulates human platelet phospholipase A2. | 1979 | Biochem. Biophys. Res. Commun. | pmid:116656 |
| Okuma M and Uchino H | Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. | 1979 | Blood | pmid:116695 |
| Best LC et al. | Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. | 1979 | Biochem. Biophys. Res. Commun. | pmid:117802 |
| Oelz O | [The arachidonic acid metabolites (prostaglandins, thromboxanes, prostacyclin, leucotrienes):basics and clinical implications (author's transl)]. | 1979 | Ther Umsch | pmid:119331 |
| Robak J and Kasperczyk H | [Prostaglandin synthetase components (author's transl)]. | 1979 | Postepy Biochem. | pmid:120943 |
| Tremoli E et al. | Platelet thromboxanes and serum-cholesterol. | 1979 | Lancet | pmid:84115 |
| Makheia AN et al. | Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. | 1979 | Lancet | pmid:86023 |
| Lewy RI et al. | Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. | 1979 | Lancet | pmid:87990 |
| Güllner HG et al. | Prostacyclin overproduction in Bartter's syndrome. | 1979 | Lancet | pmid:90861 |
| Davis TM et al. | Prostacyclin and thromboxane metabolites in diabetes. | 1979 | Lancet | pmid:90875 |
| Best L et al. | Effect of glucose on platelet thromboxane biosynthesis. | 1979 | Lancet | pmid:90876 |
| Ford-Hutchinson AW et al. | The aggregation of rat neutrophils by arachidonic acid: a possible bioassay for lipoxygenase activity. | 1979 | J. Pharm. Pharmacol. | pmid:43380 |
| Gorman RR et al. | Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction. | 1979 | Biochim. Biophys. Acta | pmid:216409 |
| Dembińska-Kièć A et al. | Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. | 1979 | Atherosclerosis | pmid:224890 |
| Fitzpatrick FA and Gorman RR | Regulatory role of cyclic adenosine 3',5'-monophosphate on the platelet cyclooxygenase and platelet function. | 1979 | Biochim. Biophys. Acta | pmid:216415 |
| Best LC et al. | Mode of action of dipyridamole on human platelets. | 1979 | Thromb. Res. | pmid:229583 |
| Marcus AJ | The role of prostaglandins in platelet function. | 1979 | Prog Hematol | pmid:230534 |
| Spagnuolo C et al. | PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. | 1979 | Prostaglandins | pmid:230539 |
| Jonsson CE et al. | Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury. | 1979 | Acta Physiol. Scand. | pmid:232367 |
| Karmazyn M and Dhalla NS | Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. | 1979 | Prostaglandins Med | pmid:233217 |
| Kass MA and Holmberg NJ | Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. | 1979 | Invest. Ophthalmol. Vis. Sci. | pmid:761971 |