Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Snider AJ et al. | Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis. | 2013 | PLoS ONE | pmid:23301082 |
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Larsen SB et al. | Increased platelet aggregation and serum thromboxane levels in aspirin-treated patients with prior myocardial infarction. | 2012 | Thromb. Haemost. | pmid:22534977 |
Macaluso M et al. | How biomarkers will change psychiatry. Part II: Biomarker selection and potential inflammatory markers of depression. | 2012 | J Psychiatr Pract | pmid:22805902 |
Shih CY and Chou TC | The antiplatelet activity of magnolol is mediated by PPAR-β/γ. | 2012 | Biochem. Pharmacol. | pmid:22750553 |
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Lee JJ et al. | Morusinol extracted from Morus alba inhibits arterial thrombosis and modulates platelet activation for the treatment of cardiovascular disease. | 2012 | J. Atheroscler. Thromb. | pmid:22472211 |
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Totani L et al. | Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. | 2012 | Thromb. Haemost. | pmid:22436970 |
Ajamieh H et al. | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | J. Gastroenterol. Hepatol. | pmid:22432744 |
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Yokoyama H et al. | Theoretical investigation of aspirin dosage regimen to exhibit optimal antiplatelet effects and decrease risk of upper gastrointestinal lesions. | 2012 | Biol. Pharm. Bull. | pmid:23047244 |