Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Barnett AH et al. Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. 1984 Lancet pmid:6145027
Schenkelaars EJ and Bonta IL Beta 2-adrenoceptor agonists reverse the leukotriene C4-induced release response of macrophages. 1984 Eur. J. Pharmacol. pmid:6151905
Teng CM et al. Biphasic effect on platelet aggregation by phospholipase a purified from Vipera russellii snake venom. 1984 Biochim. Biophys. Acta pmid:6426517
Vesterqvist O and Gréen K Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions. 1984 Prostaglandins pmid:6539491
Hsueh W et al. Identification of C3b as the major serum protein that stimulates prostaglandin and thromboxane synthesis by macrophages. 1984 Prostaglandins pmid:6240667
McCluskey ER et al. In vivo inhibition of thromboxane synthetase in infarcted canine myocardium. 1984 Biochem. Biophys. Res. Commun. pmid:6539597
Chan PK and Gentry PA Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol. 1984 Food Chem. Toxicol. pmid:6540739
Moufarrij NA et al. Thromboxane synthetase inhibition in acute focal cerebral ischemia in cats. 1984 J. Neurosurg. pmid:6542131
Hock CE and Lefer AM Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock. 1984 Circ. Shock pmid:6542462
Ito T et al. Selective thromboxane synthetase inhibitor and ischemic heart disease. 1984 Biomed. Biochim. Acta pmid:6542777
De Clerck F et al. Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. 1984 Agents Actions pmid:6543415
Menys VC and Davies JA Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben). 1984 Lab. Invest. pmid:6546403
Pedersen AK et al. Inhibition of thromboxane biosynthesis in serum: limitations of the measurement of immunoreactive 6-keto-PGF1 alpha. 1984 Thromb. Res. pmid:6546456
Novo S et al. Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs. 1984 Adv. Exp. Med. Biol. pmid:6546467
Ford WD et al. Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations. 1984 Arch. Dis. Child. pmid:6546658
Rosenblum WI and Hirsh PD Some interrelationships between glucose levels thromboxane production and prostacyclin production in normal and diabetic mice. 1984 Prostaglandins pmid:6546804
Saldeen P et al. Thromboxane production in umbilical vein grafts. 1984 Thromb. Res. pmid:6546814
Romero SD et al. Measurement of prostaglandins in the cerebrospinal fluid in cat, dog, and man. 1984 J. Neurochem. pmid:6593432
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Croft KD et al. Dietary modification of platelet and renal prostaglandins. 1984 Aust N Z J Med pmid:6393931
Garcia-Szabo RR et al. Comparison of alpha- and gamma-thrombin on lung fluid balance in anesthetized sheep. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6549181
Takeda H et al. [Comparison of centrifugal pump (bio pump) with roller pump: clinical study]. 1984 Kyobu Geka pmid:6549344
Chen LS et al. Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension. 1984 Jpn Heart J pmid:6549401
Ishihara Y et al. [Cigarette smoking and lung metabolism--effect of cigarette smoking on blood levels of 6-keto PGF1 alpha, thromboxane B2 and lipoperoxide in healthy volunteers]. 1984 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6549510
Cooper C et al. Production of prostaglandins and thromboxane by isolated cells from intracranial tumours. 1984 J. Neurol. Neurosurg. Psychiatr. pmid:6330309
Hwang DH et al. Zinc deficiency affects neither platelet arachidonic acid metabolism nor platelet aggregation in rats. 1984 J. Nutr. pmid:6582232
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Thromb. Haemost. pmid:6495252
Stahl RA et al. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. 1984 Am. J. Physiol. pmid:6507633
Kääpä P et al. Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. 1984 Pediatr. Res. pmid:6472947
Du JT et al. Sex differences in arachidonate cyclo-oxygenase products in elicited rat peritoneal macrophages. 1984 Biochim. Biophys. Acta pmid:6428458
Cuthbert AW et al. Mediators of the secretory response to kinins. 1984 Br. J. Pharmacol. pmid:6331559
Gachályi B et al. In vitro effect of cimetidine on ADP induced platelet aggregation and thromboxane A2 synthesis in man. 1984 Thromb. Res. pmid:6474407
Fitzpatrick F et al. Development of a gas chromatographic-mass spectrometric method using a stable isotope internal standard for quantitation of thromboxane B2. 1984 Thromb. Res. pmid:6474413
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Tohoku J. Exp. Med. pmid:6474447
Prinz RA et al. Platelet activation by human pancreatic fluid. 1984 J. Surg. Res. pmid:6482425
Wilson L and Huang LS Temporal response of uterine prostaglandins to estradiol treatment in the ovariectomized-pregnant rat. 1984 Prostaglandins pmid:6484214
Mackey WC et al. Aspirin decreases platelet uptake on Dacron vascular grafts in baboons. 1984 Ann. Surg. pmid:6233945
Brown C et al. Effects of age and steroid treatment on prostaglandin production by the rat uterus in relation to implantation. 1984 J. Reprod. Fertil. pmid:6583409
Luderer JR et al. Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon. 1984 Clin. Pharmacol. Ther. pmid:6428793
Ishii H et al. The effect of plasma on platelet function in hypercholesterolemic rabbits and the changes in fatty acid composition of the plasma. 1984 Thromb. Res. pmid:6234679
Del Maschio A et al. Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites. 1984 Eur. J. Pharmacol. pmid:6432556
Baughman RP et al. Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis. 1984 Am. Rev. Respir. Dis. pmid:6388445
Ninnemann JL and Stockland AE Participation of prostaglandin E in immunosuppression following thermal injury. 1984 J Trauma pmid:6231383
DiSesa VJ et al. Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization. 1984 Ann. Thorac. Surg. pmid:6388516
Takeda H et al. [Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation]. 1984 Kyobu Geka pmid:6389949
Olanoff LS et al. Effects of oleic acid on pulmonary capillary leak and thromboxanes. 1984 J. Surg. Res. pmid:6233456
Jackson EK et al. Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485. 1984 Life Sci. pmid:6330486
Hartung HP et al. Release of prostaglandin E and thromboxane from macrophages by stimulation with factor H. 1984 Clin. Exp. Immunol. pmid:6234114
Kawai C New horizons in cardiology. 1984 Int. J. Cardiol. pmid:6334040
McGoon MD and Vanhoutte PM Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine. 1984 J. Clin. Invest. pmid:6470141
Huang HC Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom. 1984 Toxicon pmid:6206608
Brunner D et al. Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus. 1984 Clin Ther pmid:6206948
Gragnoli G et al. [Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics]. 1984 Minerva Med. pmid:6207465
De Caterina R et al. Inhibition of platelet function by injectable isosorbide dinitrate. 1984 Am. J. Cardiol. pmid:6428211
Triolo G et al. Circulating immune complexes and platelet thromboxane synthesis in patients with insulin-dependent (type I) diabetes mellitus. 1984 Diabetes pmid:6611280
Coker SJ and Parratt JR The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. 1984 J. Mol. Cell. Cardiol. pmid:6366241
Alster P and Wennmalm A Effect of nicotine on the formation of prostacyclin-like activity and thromboxane in rabbit aorta and platelets. 1984 Br. J. Pharmacol. pmid:6367870
Girotti MJ et al. Effects of immunization on cardiopulmonary alterations of gram-negative endotoxemia. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6368499
Schieppati A et al. The metabolism of arachidonic acid by platelets in nephrotic syndrome. 1984 Kidney Int. pmid:6434788
Lefkowith JB et al. Macrophage-dependent arachidonate metabolism in hydronephrosis. 1984 Kidney Int. pmid:6434790
Lewis GP and Smith JR Prostaglandin endoperoxides and thromboxane A2 in thrombus formation in the hamster cheek pouch in vivo. 1984 Prostaglandins pmid:6435186
Pickard JD et al. Arterial eicosanoid production following chronic exposure to a periarterial haematoma. 1984 J. Neurol. Neurosurg. Psychiatr. pmid:6589362
MacDermot J et al. Synthesis of leukotriene B4, and prostanoids by human alveolar macrophages: analysis by gas chromatography/mass spectrometry. 1984 Prostaglandins pmid:6326199
Higashihara M et al. Interaction of Solanum tuberosum agglutinin with human platelets. 1984 Biochem. Biophys. Res. Commun. pmid:6732807
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by capillary gas chromatography and negative ion chemical ionization mass spectrometry. 1984 J. Chromatogr. pmid:6736155
Kelton JG et al. A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. 1984 Thromb. Res. pmid:6740573
Schultze G et al. Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. 1984 Transplant. Proc. pmid:6592863
Zipser RD et al. Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome. 1984 Gastroenterology pmid:6593268
Koskimies AI et al. Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility. 1984 Acta Obstet Gynecol Scand Suppl pmid:6594012
Branski D et al. Prostaglandins in small intestinal mucosa of children with celiac disease. 1984 J. Pediatr. Gastroenterol. Nutr. pmid:6594493
Woodcock BE et al. The platelet defect in acute myeloid leukaemia. 1984 J. Clin. Pathol. pmid:6595273
Steel LK et al. In vitro prostaglandin release from guinea pig parenchymal lung tissues is not stimulated by thymic peptides. 1984 Int. J. Immunopharmacol. pmid:6427124
Ogushi F et al. [In vitro release of arachidonate metabolites by human alveolar macrophages]. 1984 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6595434
Bommer J et al. Plastic filing from dialysis tubing induces prostanoid release from macrophages. 1984 Kidney Int. pmid:6595463
Kerry R et al. Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility. 1984 Biochem. Pharmacol. pmid:6147145
Seregi A et al. Decreased levels of brain cyclo-oxygenase products as a possible cause of increased seizure susceptibility in convulsion-prone gerbils. 1984 Brain Res. pmid:6430471
Willerson JT et al. Conversion from chronic to acute coronary artery disease: speculation regarding mechanisms. 1984 Am. J. Cardiol. pmid:6391133
Fareed J et al. Molecular markers of contrast media-induced adverse reactions. 1984 Semin. Thromb. Hemost. pmid:6393351
Takeda H et al. [Alternations in coagulation and fibrinolysis associated with extracorporeal circulation--the role of vasoactive prostanoids]. 1984 Rinsho Kyobu Geka pmid:6395300
Tada M et al. Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery. 1984 J. Mol. Cell. Cardiol. pmid:6398370
Stimler NP Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors. 1984 Biochem. Biophys. Res. Commun. pmid:6440564
Ylikorkala O Prostanoids in gynaecology. 1984 Ann. Clin. Res. pmid:6398666
Vapaatalo H et al. Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. 1984 Ann. Clin. Res. pmid:6398981
Mallarkey G and Smith GM In vivo platelet aggregation in the rat: dependence on extracellular divalent cation and inhibition by nonsteroidal anti-inflammatory drugs. 1984 Br. J. Pharmacol. pmid:6423018
Schafer AI et al. Unidirectional transfer of prostaglandin endoperoxides between platelets and endothelial cells. 1984 J. Clin. Invest. pmid:6423665
Driss F et al. Inhibition of platelet aggregation and thromboxane synthesis after intake of small amount of icosapentaenoic acid. 1984 Thromb. Res. pmid:6098051
Fuller RW et al. Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in culture. 1984 Clin. Sci. pmid:6091982
Dahl ML and Uotila P Salicylate does not interfere with aspirin in human blood in vivo. 1984 Prostaglandins Leukot Med pmid:6585840
Henke DC et al. Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography. 1984 Anal. Biochem. pmid:6091494
Dahl ML and Uotila P Thromboxane formation during blood clotting is decreased by verapamil. 1984 Prostaglandins Leukot Med pmid:6585842
Hall ER et al. The reduction of potential TXB2 levels when serum is preincubated at room temperature. 1984 Prostaglandins Leukot Med pmid:6585846
Codde JP et al. Validation of the direct radioimmunoassay of prostanoids in serum and kidney. 1984 Prostaglandins Leukot Med pmid:6587406
Shaala S et al. Local effect of thromboxane B2 on the contractility of the human non pregnant uterus. 1984 Prostaglandins Leukot Med pmid:6587408
Higgins AJ et al. Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate. 1984 Cornell Vet pmid:6587959
Meydani M et al. Effects of dietary methionine, methylmercury, and atrazine on ex-vivo synthesis of prostaglandin E1 and thromboxane B2. 1984 Prostaglandins Leukot Med pmid:6588393
Jouve R et al. Thromboxane B2, 6-keto-PGF1 alpha, PGE2, PGF2 alpha, and PGA1 plasma levels in arteriosclerosis obliterans: relationship to clinical manifestations, risk factors, and arterial pathoanatomy. 1984 Am. Heart J. pmid:6581715
Ylikorkala O and Tenhunen A Follicular fluid prostaglandins in endometriosis and ovarian hyperstimulation. 1984 Fertil. Steril. pmid:6363141
Turk J et al. Arachidonic acid metabolism in isolated pancreatic islets. I. Identification and quantitation of lipoxygenase and cyclooxygenase products. 1984 Biochim. Biophys. Acta pmid:6329307
Anderson CB et al. Renal thromboxane synthesis in excised kidney distal to renovascular lesions. 1984 JAMA pmid:6726983
Grignani G et al. Activation of platelet prostaglandin biosynthesis pathway during neoplastic cell-induced platelet aggregation. 1984 Thromb. Res. pmid:6729776