Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Diseases in Twins D004200 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Tremoli E et al. Metformin reduces platelet hypersensitivity in hypercholesterolemic rabbits. 1982 Atherosclerosis pmid:7073794
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Peterson MB et al. Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. 1982 Am. J. Physiol. pmid:7051860
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
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Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
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Mest HJ et al. Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. 1982 Prostaglandins Leukot Med pmid:6955811
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White JG and Rao GH Effects of a microtubule stabilizing agent on the response of platelets to vincristine. 1982 Blood pmid:6124288
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Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
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Srivastava KC and Awasthi KK A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. 1982 Prostaglandins Leukot Med pmid:6818563
Neri Serheri GG et al. Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. 1982 Haemostasis pmid:6279476
Dore-Duffy P Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. 1982 Prostaglandins Leukot Med pmid:6281810
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Miller OV et al. Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence. 1982 Biochim. Biophys. Acta pmid:6285985
Jackson CA et al. Relationship between platelet aggregation, thromboxane synthesis and albumin concentration in nephrotic syndrome. 1982 Br. J. Haematol. pmid:6810912
Robinson C et al. Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. 1982 Biochim. Biophys. Acta pmid:6751406
Schafer AI et al. Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets. 1982 Biochim. Biophys. Acta pmid:6812645
Uyama O et al. Plasma concentrations of 6-keto-prostaglandin F1 alpha in patients with hypertension, cerebrovascular disease or Takayasu's arteritis. 1982 Jan 1-15 Thromb. Res. pmid:6121391
Sakai K et al. Roles of endogenous prostacyclin and thromboxane A2 in the ischemic canine heart. 1982 Jan-Feb J. Cardiovasc. Pharmacol. pmid:6176788
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Shohami E et al. The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain. 1982 Jul-Aug Stroke pmid:6896589
Mest HJ et al. [Effect of stress on blood level of prostaglandins in students during exams]. 1982 May-Jun Farmakol Toksikol pmid:7095121
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
Mest HJ et al. The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man. 1983 Klin. Wochenschr. pmid:6341702
Hartung HP et al. Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. 1983 J. Immunol. pmid:6343486
Nuotto E et al. Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. 1983 Eur. J. Clin. Pharmacol. pmid:6628518
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Wallis RB Mechanisms of action of sulphinpyrazone. 1983 Thromb. Res. Suppl. pmid:6415857
Miller JB et al. Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. 1983 Biol. Reprod. pmid:6688954
Davì G et al. The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. 1983 Thromb. Haemost. pmid:6417815
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Hartung HP et al. Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. 1983 J. Immunol. pmid:6600482