Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Choline Deficiency D002796 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Svensson J and Samuelsson K Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. 1983 Thromb. Res. pmid:20218005
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Saldeen P et al. Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. 1983 Thromb. Res. pmid:6658723
Preston FE Aspirin, prostaglandins, and peripheral gangrene. 1983 Am. J. Med. pmid:6859070
Winter M et al. Synthesis of thromboxane B2 in uraemia and the effects of dialysis. 1983 Thromb. Res. pmid:6868024
Nordøy A et al. Platelets and coagulation in patients with familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6188328
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
Hartung HP and Toyka KV Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. 1983 Eur. J. Pharmacol. pmid:6191998
Tanganelli I et al. [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. 1983 Boll. Soc. Ital. Biol. Sper. pmid:6194801
Wientroub S et al. Changes in tissue concentration of prostaglandins during endochondral bone differentiation. 1983 Biochem. Biophys. Res. Commun. pmid:6582850
Horellou MH et al. Familial and constitutional bleeding disorder due to platelet cyclo-oxygenase deficiency. 1983 Am. J. Hematol. pmid:6404162
Salmon JA et al. The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. 1983 J. Pharm. Pharmacol. pmid:6141244
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Nerlich M et al. Effect of thermal injury on endotoxin-induced lung injury. 1983 Surgery pmid:6337423
Harlan J et al. Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. 1983 Br J Clin Pharmacol pmid:6337602
Ball HA et al. Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. 1983 Br J Clin Pharmacol pmid:6337603
Stratta P et al. Warning: platelet factor 4, beta-thromboglobulin and thromboxane in donor's plasma units. 1983 Thromb. Haemost. pmid:6189235
Dodd NJ et al. Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. 1983 Br J Clin Pharmacol pmid:6337605
Ylikorkala O et al. Maternal prostacyclin, thromboxane, and placental blood flow. 1983 Am. J. Obstet. Gynecol. pmid:6338724
de Kergommeaux BD et al. Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery. 1983 Prostaglandins Leukot Med pmid:6410417
Boughton-Smith NK et al. Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. 1983 Gut pmid:6416934
Bromberg Y and Pick E Unsaturated fatty acids as second messengers of superoxide generation by macrophages. 1983 Cell. Immunol. pmid:6307532
Vlasses PH et al. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6308685
Huval WV et al. Thromboxane mediation of cardiovascular dysfunction following aspiration. 1983 Surgery pmid:6308843
Hartung HP Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. 1983 FEBS Lett. pmid:6309563
Ahlquist DA et al. Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. 1983 Am. J. Physiol. pmid:6401937
Fischer S et al. The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in man. 1983 Circulation pmid:6352080
Davi' G et al. Platelet activation after adrenergic stimulation in hypertensive patients: effects of acebutolol. 1983 Eur. Heart J. pmid:6352266
FitzGerald GA et al. Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. 1983 J. Clin. Invest. pmid:6355181
Jouve R et al. [Plasma thromboxane B2 and capacity of the aorta to produce prostacyclin in arteriopathies of the lower extremities]. 1983 J Mal Vasc pmid:6355348
Mehta J et al. Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. 1983 Prostaglandins Leukot Med pmid:6356153
Henriksen RA and Brotherton AF Evidence that activation of platelets and endothelium by thrombin involves distinct sites of interaction. Studies with the dysthrombin, Thrombin Quick I. 1983 J. Biol. Chem. pmid:6358210
Kaliman J et al. [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. 1983 Wien. Klin. Wochenschr. pmid:6359724
Ylikorkala O et al. Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors. 1983 Gynecol. Oncol. pmid:6360817
Tada M et al. [Biochemistry of coronary artery disease--prostaglandins]. 1983 Rinsho Byori pmid:6361336
Hardisty RM et al. A new congenital defect of platelet secretion: impaired responsiveness of the platelets to cytoplasmic free calcium. 1983 Br. J. Haematol. pmid:6830700
Patrono C et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221569
Fletcher JR et al. Thromboxane inhibition in gram-negative sepsis fails to improve survival. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221586
Jørgensen KA et al. The survival of pig to rabbit renal xenografts during inhibition of thromboxane synthesis. 1983 Thromb. Res. pmid:6364449
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Hornstra G et al. Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221593
Mandrovnaia NV et al. [Age-related changes in prostacyclin and thromboxane B2 biosynthesis under normal conditions and in arterial hypertension]. 1983 Kardiologiia pmid:6366325
Tremoli E et al. North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221594
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
McDonald JW et al. Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. 1983 Circ. Res. pmid:6687354
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). 1983 Br J Clin Pharmacol pmid:6687429
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Sinzinger H and Firbas W [Cells of the vascular wall synthesize thromboxane]. 1983 Wien. Klin. Wochenschr. pmid:6369802
Bruckner G et al. Dietary trilinoelaidate: effects on hematological parameters, serum eicosanoids and tissue fatty acid composition in rats. 1983 J. Nutr. pmid:6687476
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Bessin P et al. Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs. 1983 Eur. J. Pharmacol. pmid:6687572
Ingerman-Wojenski CM et al. Early morphological changes in the endothelium of a peripheral artery of rabbits fed an atherogenic diet. 1983 Exp. Mol. Pathol. pmid:6687574
Schumacher WA and Lucchesi BR Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. 1983 J. Pharmacol. Exp. Ther. pmid:6418881
Sakamoto T [Studies on platelet function in toxemia of pregnancy]. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6223964
Mehta P et al. Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. 1983 J. Lab. Clin. Med. pmid:6411841
Hartung HP and Toyka KV Tuftsin stimulates the release of oxygen radicals and thromboxane from macrophages. 1983 Immunol. Lett. pmid:6687720
Winchester JF et al. Early indicators of renal allograft rejection. 1983 Kidney Int. Suppl. pmid:6224041
D'Angelo A et al. Effect of des-amino-D-arginine vasopressin (DDAVP) on plasma levels of platelet and endothelial cell release products. 1983 Thromb. Haemost. pmid:6687766
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Ku EC et al. Characterization of imidazo[1,5-a]pyridine-5-hexanoic acid (CGS 13080) as a selective thromboxane synthetase inhibitor using in vitro and in vivo biochemical models. 1983 Biochem. Biophys. Res. Commun. pmid:6687803
Anderegg K et al. Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat. 1983 Br. J. Pharmacol. pmid:6687819
Todd MH et al. The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs. 1983 Thromb. Res. pmid:6687961
Halushka PV et al. Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. 1983 Am. J. Med. pmid:6687979
Tsukatani E Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6688085
Fischer S et al. In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. 1983 Biochem. Pharmacol. pmid:6688182
Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
Srivastava KC and Awasthi KK Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. 1983 J. Chromatogr. pmid:6688256
Wilson L and Huang LS Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. 1983 Prostaglandins pmid:6688474
Robinson C and Hoult JR Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung. 1983 Biochim. Biophys. Acta pmid:6652102
Higgs GA et al. The source of thromboxane and prostaglandins in experimental inflammation. 1983 Br. J. Pharmacol. pmid:6652359
Anton RF et al. In vivo regional levels of PGE and thromboxane in mouse brain: effect of decapitation, focused microwave fixation, and indomethacin. 1983 Prostaglandins pmid:6658001
Mahoney D et al. Influence of dietary polyunsaturated fatty acids on renal & aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats. 1983 Prostaglandins pmid:6658002
Martin JF et al. The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. 1983 Thromb. Res. pmid:6658722
Cohen RA et al. 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. 1983 Am. J. Physiol. pmid:6660308
Cortellaro M et al. Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment. 1983 Thromb. Haemost. pmid:6665767
De Caterina R et al. Antiplatelet effects of isosorbide dinitrate in man. 1983 Z Kardiol pmid:6666233
Smith EF et al. RCS from human platelets: is it only thromboxane? 1983 Eur. J. Pharmacol. pmid:6667711
Sakanishi N et al. [Effect of reduced glutathione on endotoxin shock]. 1983 Masui pmid:6668649
Moonen P et al. An improved method for separation of thromboxane B2 by reversed phase liquid chromatography. 1983 Prostaglandins pmid:6669711
Karmali RA et al. Prostaglandins in breast cancer: relationship to disease stage and hormone status. 1983 Br. J. Cancer pmid:6416285
Gethmann U et al. Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro. 1983 Arch. Gynecol. pmid:6320749
Viinikka L et al. Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. 1983 Prostaglandins Leukot Med pmid:6576385
Fukumoto S and Tanaka K Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. 1983 Prostaglandins Leukot Med pmid:6576388
Kinney EL et al. Mechanism of action of amrinone: role of thromboxane synthetase inhibition. 1983 Prostaglandins Leukot Med pmid:6576389
Hawkey CJ et al. Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease. 1983 Gut pmid:6578172
Zijlstra FJ et al. Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip. 1983 Prostaglandins Leukot Med pmid:6578519
Roy L et al. Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. 1983 Am. J. Cardiol. pmid:6823861
Reuben SR et al. Effects of dazoxiben on exercise performance in chronic stable angina. 1983 Br J Clin Pharmacol pmid:6402000
Mahoney DP et al. Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. 1983 Prostaglandins Leukot Med pmid:6579570
Güllner HG et al. Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. 1983 Prostaglandins Leukot Med pmid:6580653
Rojas J et al. Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. 1983 Pediatr. Res. pmid:6402752
Sakanishi N et al. Thromboxane A2 and hemodynamic-biochemical parameters in canine endotoxin shock. 1983 Bull. Tokyo Med. Dent. Univ. pmid:6580966
Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Orlandi M et al. Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes. 1983 Prostaglandins Leukot Med pmid:6583712
Männistö J and Uotila P Cigarette smoke ventilation decreases thromboxane B2 metabolism in isolated rat lungs. 1983 Prostaglandins Leukot Med pmid:6583713
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
Sharon P et al. Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer. 1983 Scand. J. Gastroenterol. pmid:6584967
Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Hayashi Y et al. Enzyme immunoassay of thromboxane B2. 1983 Biochim. Biophys. Acta pmid:6407530
Carr BR et al. Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. 1983 J. Clin. Endocrinol. Metab. pmid:6313732