| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Femoral Fractures | D005264 | 7 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Acidosis | D000138 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Staphylococcal Infections | D013203 | 15 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| von Aulock S et al. | Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo. | 2003 | J. Immunol. Methods | pmid:12799039 |
| Yregård L et al. | Influence of local anaesthetics on inflammatory activity postburn. | 2003 | Burns | pmid:12781610 |
| Vigorita MG et al. | Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. | 2003 | Bioorg. Med. Chem. | pmid:12614885 |
| Vass G et al. | Comparison of nasal and oral inhalation during exhaled breath condensate collection. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12493648 |
| Gama de Abreu M et al. | One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. | 2003 | Anesth. Analg. | pmid:12505956 |
| Szebeni J et al. | Complement activation during hemorrhagic shock and resuscitation in swine. | 2003 | Shock | pmid:14501949 |
| Vani G et al. | Histone H1 modulates immune status in experimental breast cancer. | 2003 | Chemotherapy | pmid:14504437 |
| Xia Z et al. | Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. | 2003 | J. Thorac. Cardiovasc. Surg. | pmid:14666012 |
| Chen L et al. | Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12485821 |
| Lombard JH et al. | High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12456391 |
| Jones AE et al. | Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12639842 |
| Sheu JR et al. | Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. | 2003 | Exp. Biol. Med. (Maywood) | pmid:14681547 |
| De La Cruz JP et al. | Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers. | 2003 | Fundam Clin Pharmacol | pmid:12803576 |
| Guyton K et al. | Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. | 2003 | Shock | pmid:12813370 |
| Fujimoto Y et al. | Effects of endocrine disruptors on arachidonic acid metabolism in rabbit platelets. | 2003 | Toxicol. Appl. Pharmacol. | pmid:12781627 |
| Stephenson AH et al. | Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12609822 |
| Cipollone F et al. | Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. | 2003 | Circulation | pmid:12515743 |
| Fike CD et al. | Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12388340 |
| Nagase T et al. | A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12505870 |
| Dai H et al. | Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. | 2003 | Postgrad Med J | pmid:13679549 |
| Liu H et al. | Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. | 2003 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:12973949 |
| Hart RG et al. | Aspirin dosage and thromboxane synthesis in patients with vascular disease. | 2003 | Pharmacotherapy | pmid:12741431 |
| Pfeiffer S et al. | Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. | 2003 | Transplantation | pmid:12698079 |
| Arifah AK et al. | Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12667184 |
| Davì G et al. | Platelet activation in obese women: role of inflammation and oxidant stress. | 2002 Oct 23-30 | JAMA | pmid:12387653 |
| Hayashi M et al. | Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. | 2002 Nov-Dec | Eur. J. Haematol. | pmid:12460234 |
| Wolfram RM et al. | Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. | 2002 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12144875 |
| Alarayyed NA et al. | Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. | 2002 Aug-Sep | Platelets | pmid:12189011 |
| Ersöz G et al. | Effect of submaximal and incremental upper extremity exercise on platelet function and the role of blood shear stress. | 2002 | Thromb. Res. | pmid:12676189 |
| Connolly E et al. | Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty. | 2002 | J. Pharmacol. Exp. Ther. | pmid:11805196 |
| Pinheiro RM and Calixto JB | Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. | 2002 | Inflamm. Res. | pmid:12558194 |
| Saldeen P et al. | Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism. | 2002 | J. Matern. Fetal. Neonatal. Med. | pmid:12530613 |
| Bermejo BP et al. | Sesquiterpenes from Jasonia glutinosa: in vitro anti-inflammatory activity. | 2002 | Biol. Pharm. Bull. | pmid:11824534 |
| Ersöz G et al. | The effect of submaximal exercise on platelet aggregation during late follicular and midluteal phases in women. | 2002 | Thromb. Res. | pmid:12590951 |
| Küsters S et al. | Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. | 2002 | Arzneimittelforschung | pmid:11878205 |
| Lassus P et al. | Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants. | 2002 | Early Hum. Dev. | pmid:11893431 |
| Venuto R et al. | Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11893597 |
| Wainwright CL et al. | NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs. | 2002 | Br. J. Pharmacol. | pmid:11959790 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of midazolam in human platelets. | 2002 | Anesthesiology | pmid:11873041 |
| Horiguchi T et al. | Study on the usefulness of seratrodast in the treatment of chronic pulmonary emphysema. | 2002 | Arzneimittelforschung | pmid:12442639 |
| Zaitsu M et al. | Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468261 |
| Thomson M et al. | The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468270 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of magnesium in human platelets. | 2002 | Br. J. Haematol. | pmid:12472585 |
| Fiorucci S et al. | NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide. | 2002 | Circulation | pmid:12473561 |
| Rouvier J et al. | Aspirin resistance. | 2002 | Circulation | pmid:12473569 |
| Celik I et al. | Effects of ibuprofen on the physiology and outcome of rabbit endotoxic shock. | 2002 | BMC Infect. Dis. | pmid:12445332 |
| Dai CF et al. | [Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. | 2002 | Zhonghua Nan Ke Xue | pmid:12479132 |
| Khan I et al. | Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam. | 2002 | Scand. J. Gastroenterol. | pmid:12523593 |
| Miyataka M et al. | Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2. | 2002 | Hypertension | pmid:11897764 |
| Leahy KM et al. | Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. | 2002 | Cancer Res. | pmid:11830509 |
| Ozaki N et al. | Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428679 |
| Ma LP et al. | Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. | 2002 | J Assoc Acad Minor Phys | pmid:11852667 |
| De La Cruz JP et al. | Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction. | 2002 | Br. J. Pharmacol. | pmid:12429581 |
| Canbaz M et al. | Effects of tibolone on thromboxane B(2) levels in postmenopausal women. | 2002 | Gynecol. Obstet. Invest. | pmid:11803222 |
| Huang F et al. | Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. | 2002 | J. Cardiovasc. Pharmacol. | pmid:11791012 |
| Bayorh MA et al. | 1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats. | 2002 | Peptides | pmid:11814618 |
| Jeng JH et al. | Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. | 2002 | Free Radic. Biol. Med. | pmid:11978487 |
| Streppa HK et al. | Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. | 2002 | Am. J. Vet. Res. | pmid:16206787 |
| Jiang Z et al. | [The changes of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha(6-keto-PGF1 alpha) in the lungs of rats drowned in hypothermic-sea-water]. | 2002 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:14694611 |
| Saareks V et al. | Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. | 2002 | Pharmacol. Toxicol. | pmid:12403056 |
| Kudolo GB et al. | Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. | 2002 | Thromb. Res. | pmid:12590952 |
| Sinzinger H | Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12445490 |
| Obase Y et al. | Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. | 2002 | Chest | pmid:11796443 |
| Gordon SM et al. | Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: replicate clinical trials in a tissue injury model. | 2002 | Clin. Pharmacol. Ther. | pmid:12189364 |
| Van Hecken A et al. | Effects of enteric-coated, low-dose aspirin on parameters of platelet function. | 2002 | Aliment. Pharmacol. Ther. | pmid:12197849 |
| Gómez-Gaviro MV et al. | Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. | 2002 | J. Biol. Chem. | pmid:12147693 |
| Khan AA et al. | In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. | 2002 | Clin. Pharmacol. Ther. | pmid:12152003 |
| Vecino AM et al. | Phospholipase A2 activity in platelets of patients with uremia. | 2002 | Platelets | pmid:12487789 |
| Rinder HM et al. | Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. | 2002 | J Clin Pharmacol | pmid:12162470 |
| Wong DA et al. | Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2). | 2002 | J. Exp. Med. | pmid:12163563 |
| Kiemer AK et al. | Inhibition of cyclooxygenase-2 by natriuretic peptides. | 2002 | Endocrinology | pmid:11861506 |
| Huang K et al. | Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. | 2002 | Atherosclerosis | pmid:11947907 |
| Hu X et al. | [The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]. | 2002 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11953098 |
| Burleigh ME et al. | Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. | 2002 | Circulation | pmid:11956125 |
| Jankov RP et al. | Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. | 2002 | Am. J. Respir. Crit. Care Med. | pmid:12119234 |
| Giardiello FM et al. | Primary chemoprevention of familial adenomatous polyposis with sulindac. | 2002 | N. Engl. J. Med. | pmid:11932472 |
| Signorello MG et al. | Effect of homocysteine on arachidonic acid release in human platelets. | 2002 | Eur. J. Clin. Invest. | pmid:11952814 |
| Yamasaki M et al. | No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. | 2002 | Eur. J. Pharmacol. | pmid:11937106 |
| Eikelboom JW et al. | Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. | 2002 | Circulation | pmid:11940542 |
| Knijff-Dutmer EA et al. | Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis. | 2002 | Rheumatology (Oxford) | pmid:11961179 |
| Hayashi M et al. | The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. | 2002 | Acta Obstet Gynecol Scand | pmid:11966476 |
| Leese PT et al. | Valdecoxib does not impair platelet function. | 2002 | Am J Emerg Med | pmid:12098171 |
| Tsukamoto H et al. | Simultaneous quantification of prostaglandins, isoprostane and thromboxane in cell-cultured medium using gas chromatography-mass spectrometry. | 2002 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:12076690 |
| Sakai H et al. | E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon. | 2002 | Br. J. Pharmacol. | pmid:12023941 |
| Jung K et al. | The effect of dietary intervention through the modification of fatty acids composition and antioxidant vitamin intake on plasma TXB(2) level in Korean postmenopausal women with hypercholesterolemia. | 2002 | J. Korean Med. Sci. | pmid:12068132 |
| Jung YS et al. | Antithrombotic effect of onion in streptozotocin-induced diabetic rat. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12054917 |
| van Kraaij DJ et al. | A comparison of the effects of nabumetone vs meloxicam on serum thromboxane B2 and platelet function in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:12047490 |
| Appleyard CB et al. | Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis. | 2002 | Dig. Dis. Sci. | pmid:12353846 |
| Valeri CR et al. | Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy. | 2002 | Transfusion | pmid:12430680 |
| Wilner KD et al. | Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:12211219 |
| Molina V et al. | D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12213431 |
| Koizumi T et al. | Inhibition of endogenous nitric oxide during endotoxemia in awake sheep - effects of Nomega-nitro-l-arginine on the distribution of pulmonary vascular resistance and prostanoid products. | 2002 | Exp. Lung Res. | pmid:12217213 |
| Khan I et al. | Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. | 2002 | Nephron | pmid:12218313 |
| Yokoyama C et al. | Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. | 2002 | Circulation | pmid:12403673 |
| Evgenov OV et al. | Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. | 2002 | Eur. Respir. J. | pmid:12412689 |
| Bergh K et al. | Production of prostaglandin e(2) by iridial melanocytes exposed to latanoprost acid, a prostaglandin F(2 alpha) analogue. | 2002 | J Ocul Pharmacol Ther | pmid:12419090 |
| Chen TL et al. | [Effects of fast decompression on prostaglandins content in cerebral tissue of guinea pigs]. | 2002 | Space Med Med Eng (Beijing) | pmid:12222577 |
| Kim H et al. | Effect of mannitol on Helicobacter pylori-induced cyclooxygenase-2 expression in gastric epithelial AGS cells. | 2002 | Pharmacology | pmid:12393940 |
| Shashikant MP et al. | Physicochemical properties of perfluorochemical liquids influence ventilatory requirements, pulmonary mechanics, and microvascular permeability during partial liquid ventilation following intestinal ischemia/reperfusion injury. | 2002 | Crit. Care Med. | pmid:12394959 |
| Vaughan JE and Walsh SW | Oxidative stress reproduces placental abnormalities of preeclampsia. | 2002 | Hypertens Pregnancy | pmid:12517328 |