Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Luzak B et al. | Xanthohumol from hop cones (Humulus lupulus L.) prevents ADP-induced platelet reactivity. | 2017 | Arch. Physiol. Biochem. | pmid:27855519 |
Yu M et al. | The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations. | 2017 | Int J Mol Sci | pmid:28287417 |
Jin M et al. | Effects of pulmonary static inflation with 50% xenon on oxygen impairment during cardiopulmonary bypass for stanford type A acute aortic dissection: A pilot study. | 2017 | Medicine (Baltimore) | pmid:28272227 |
Kramkowski K et al. | Short-term treatment with nitrate is not sufficient to induce in vivo antithrombotic effects in rats and mice. | 2017 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:27743016 |
Obilade OA et al. | Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy. | 2017 | PLoS ONE | pmid:28880908 |
Xie P et al. | Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra. | 2017 | Biomed Res Int | pmid:28299338 |
Kosik-Bogacka DI et al. | The inflammatory effect of infection with Hymenolepis diminuta via the increased expression and activity of COX-1 and COX-2 in the rat jejunum and colon. | 2016 | Exp. Parasitol. | pmid:27466058 |
Pallio G et al. | Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis. | 2016 | Eur. J. Pharmacol. | pmid:27450484 |
Ferrari D et al. | Cyanidin-3-O-glucoside inhibits NF-kB signalling in intestinal epithelial cells exposed to TNF-α and exerts protective effects via Nrf2 pathway activation. | 2016 | Toxicol. Lett. | pmid:27793764 |
Peng LL et al. | Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. | 2016 | Acta Pharmacol. Sin. | pmid:27641736 |
Maga P et al. | 11-dehydro thromboxane B2 levels after percutaneous transluminal angioplasty in patients with peripheral arterial occlusive disease during a one year follow-up period. | 2016 | J. Physiol. Pharmacol. | pmid:27511998 |
Morel A et al. | The increased level of COX-dependent arachidonic acid metabolism in blood platelets from secondary progressive multiple sclerosis patients. | 2016 | Mol. Cell. Biochem. | pmid:27507559 |
Gonzalez-Paredes FJ et al. | Contribution of Cyclooxygenase End Products and Oxidative Stress to Intrahepatic Endothelial Dysfunction in Early Non-Alcoholic Fatty Liver Disease. | 2016 | PLoS ONE | pmid:27227672 |
Kakouros N et al. | Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery. | 2016 | J Am Heart Assoc | pmid:27068626 |
Becerra AZ et al. | Increases in ambient particulate matter air pollution, acute changes in platelet function, and effect modification by aspirin and omega-3 fatty acids: A panel study. | 2016 | J. Toxicol. Environ. Health Part A | pmid:27029326 |
Homoródi N et al. | The lack of aspirin resistance in patients with coronary artery disease. | 2016 | J Transl Med | pmid:26980433 |
Wannhoff A et al. | Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt. | 2016 | Aliment. Pharmacol. Ther. | pmid:26919285 |
Taneja A et al. | Biomarker exposure-response relationships as the basis for rational dose selection: Lessons from a simulation exercise using a selective COX-2 inhibitor. | 2016 | J Clin Pharmacol | pmid:26331692 |
Siewiera K et al. | Long-term untreated streptozotocin-diabetes leads to increased expression and elevated activity of prostaglandin H2 synthase in blood platelets. | 2016 | Platelets | pmid:26325148 |
Sugita R et al. | A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models. | 2016 | J. Pharmacol. Sci. | pmid:26906248 |