Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mitchell MD et al. | Possible role for prostacyclin in human parturition. | 1978 | Prostaglandins | pmid:373020 |
Davidson EM et al. | The release of thromboxane B2 by rabbit peritoneal polymorphonuclear leucocytes [proceedings]. | 1978 | Br. J. Pharmacol. | pmid:667479 |
Goldstein IM et al. | Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. | 1978 | J. Exp. Med. | pmid:702055 |
Anhut H et al. | Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. | 1978 | Prostaglandins | pmid:704912 |
Nelson NA et al. | Synthesis of thromboxane B2 metabolites. | 1978 | Prostaglandins | pmid:704927 |
Marion J and Wolfe LS | Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. | 1978 | Prostaglandins | pmid:704928 |
Agradi E et al. | Influence of short term dietary supplementation of different lipids on aggregation and arachidonic acid metabolism in rabbit platelets. | 1978 | Prostaglandins | pmid:748984 |
Fitzpatrick FA and Gorman RR | A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. | 1978 | Biochim. Biophys. Acta | pmid:629996 |
Malik KU | Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. | 1978 | Circ. Res. | pmid:27321 |
Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |