Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Smith AJ et al. | Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma. | 1995 | Br J Obstet Gynaecol | pmid:8534627 |
| Landoni MF and Lees P | Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling. | 1995 | Equine Vet. J. | pmid:8536660 |
| Shimizu Y et al. | Nafamostat mesilate prevents warm ischemia-reperfusion injury in canine pancreas autotransplantation. | 1995 | Transplant. Proc. | pmid:8539906 |
| Blache D et al. | Occurrence and biological effects of cholesteryl sulfate on blood platelets. | 1995 | Biochim. Biophys. Acta | pmid:8541337 |
| Lees P et al. | Pharmacodynamics and pharmacokinetics of carprofen in the horse. | 1994 | Equine Vet. J. | pmid:8542839 |
| Daugschies A | Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro. | 1995 | Exp. Parasitol. | pmid:8542999 |
| Kato A et al. | Role of thromboxane A2 and prostacyclin in uninephrectomy-induced attenuation of ischemic renal injury. | 1995 | Kidney Int. | pmid:8544417 |
| Morioka K et al. | Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8551788 |
| Wang TL et al. | The evolution of platelet aggregability in patients undergoing catheter ablation for supraventricular tachycardia with radiofrequency energy: the role of antiplatelet therapy. | 1995 | Pacing Clin Electrophysiol | pmid:8552510 |
| Liu W et al. | [Effects of selenium and vitamin E on arachidonic acid metabolism in experimental myocardial ischaemia]. | 1995 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:8556938 |
| Satterwhite JH and Boudinot FD | Effects of age on the pharmacodynamics of naproxen in the rat. | 1995 Sep-Oct | Exp. Gerontol. | pmid:8557098 |
| Kawikova I et al. | Bradykinin-induced release of thromboxane B2 into bronchoalveolar lavage fluid of guinea pigs: relationship to airflow obstruction. | 1995 | Eur. J. Pharmacol. | pmid:8566097 |
| Glaser K et al. | Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1. | 1995 | Eur. J. Pharmacol. | pmid:8566109 |
| Altavilla D et al. | G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-alpha biosynthesis. | 1995 | Eur. J. Pharmacol. | pmid:8566149 |
| Kobayashi I et al. | Saiboku-To, a herbal extract mixture, selectively inhibits 5-lipoxygenase activity in leukotriene synthesis in rat basophilic leukemia-1 cells. | 1995 | J Ethnopharmacol | pmid:8569245 |
| Sorem KA and Siler-Khodr TM | Placental prostanoid release in severe intrauterine growth retardation. | 1995 | Placenta | pmid:8570572 |
| Nakano T et al. | Effects of platelet depletion on PMA-induced acute lung injury in awake sheep. | 1995 | Respir Physiol | pmid:8570923 |
| Umeda F et al. | Prostaglandins and diabetic nephropathy. | 1995 Oct-Dec | J. Diabetes Complicat. | pmid:8573760 |
| Lin Y and Sun M | [Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase]. | 1995 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:8575046 |
| Kanamori S et al. | Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa. | 1995 | Clin. Exp. Pharmacol. Physiol. | pmid:8575110 |
| Gil B et al. | Effects of marine 2-polyprenyl-1,4-hydroquinones on phospholipase A2 activity and some inflammatory responses. | 1995 | Eur. J. Pharmacol. | pmid:8575515 |
| Somova L | Effects of iloprost on salt-sensitive Dahl rats. | 1995 | Methods Find Exp Clin Pharmacol | pmid:8577205 |
| Gold MS et al. | Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8577723 |
| Patrono C et al. | Characterization of biochemical and functional effects of antiplatelet drugs as a key to their clinical development. | 1995 | Thromb. Haemost. | pmid:8578493 |
| Cenni E et al. | Platelet and coagulation factor variations induced in vitro by polyethylene terephthalate (Dacron) coated with pyrolytic carbon. | 1995 | Biomaterials | pmid:8580259 |
| Lin Y | Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase. | 1995 | Chin. Med. Sci. J. | pmid:8580482 |
| Lu CS et al. | [Experimental study on anti-atherosclerotic effect of tongmai jiangzhi oral liquor]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8580696 |
| Panara MR et al. | Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin endoperoxide synthases. | 1995 | Br. J. Pharmacol. | pmid:8581280 |
| Hsu LY et al. | 2-Heteroaryl 2-substituted phenylketone derivatives and their inhibitory activity on platelet aggregation. | 1995 | J. Pharm. Pharmacol. | pmid:8583390 |
| Friedman M et al. | Neutrophil adhesion blockade with NPC 15669 decreases pulmonary injury after total cardiopulmonary bypass. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8583821 |
| Davì G et al. | Demonstration of Rickettsia Conorii-induced coagulative and platelet activation in vivo in patients with Mediterranean spotted fever. | 1995 | Thromb. Haemost. | pmid:8584998 |
| Habib A et al. | Increased expression of inducible cyclooxygenase-2 in human endothelial cells by antiphospholipid antibodies. | 1995 | Thromb. Haemost. | pmid:8585020 |
| Cargile JL et al. | Effects of tumor necrosis factor blockade on interleukin 6, lactate, thromboxane, and prostacyclin responses in miniature horses given endotoxin. | 1995 | Am. J. Vet. Res. | pmid:8585654 |
| Landoni MF et al. | Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587147 |
| Kane GC et al. | Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor. | 1995 | Prostaglandins | pmid:8588068 |
| Myers SI et al. | Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures. | 1995 | Prostaglandins | pmid:8588069 |
| Jawerbaum A et al. | Hyperglycemia promotes elevated generation of TXA2 in isolated rat uteri. | 1995 | Prostaglandins | pmid:8588071 |
| Pettigrew LC et al. | Delayed elevation of platelet activating factor in ischemic hippocampus. | 1995 | Brain Res. | pmid:8590061 |
| Pfister SL and Campbell WB | Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. | 1996 | Hypertension | pmid:8591886 |
| Zhou W et al. | Evidence for altered cellular calcium in the pathogenetic mechanism of acute pancreatitis in rats. | 1996 | J. Surg. Res. | pmid:8592406 |
| Yokoyama I et al. | Beneficial effect of donor pretreatment with thromboxane A2 synthase inhibitor on the graft survival in pig liver transplantation. | 1996 | J. Surg. Res. | pmid:8592420 |
| Landoni MF and Lees P | Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves. | 1995 | Chirality | pmid:8593252 |
| Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
| Berti F et al. | Protective effect of furosemide combined with non-steroidal anti-inflammatory drugs administered by inhalation route on guinea-pigs anaphylaxis model. | 1995 | Arzneimittelforschung | pmid:8595068 |
| Jesse RL et al. | Dehydroepiandrosterone inhibits human platelet aggregation in vitro and in vivo. | 1995 | Ann. N. Y. Acad. Sci. | pmid:8597466 |
| Makheia AN et al. | Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. | 1979 | Lancet | pmid:86023 |
| Sreedhara R et al. | Uremic patients have decreased shear-induced platelet aggregation mediated by decreased availability of glycoprotein IIb-IIIa receptors. | 1996 | Am. J. Kidney Dis. | pmid:8604704 |
| Sanderud J et al. | D-penicillamine inhibits the action of reactive oxygen species in the pig pulmonary circulation. | 1995 | J Perinat Med | pmid:8606345 |
| Huang JZ et al. | Study on characteristics of blast-fragment combined injury in dogs. | 1996 | J Trauma | pmid:8606426 |
| Tarnow P et al. | Effects of D-myo-Inositol-1,2,6-triphosphate on eicosanoid formation in burned skin. | 1996 | J. Surg. Res. | pmid:8606494 |
| Rocca B et al. | Increased thromboxane biosynthesis in essential thrombocythemia. | 1995 | Thromb. Haemost. | pmid:8607099 |
| Cochran JB et al. | Age-related mortality and adherent splenic cell mediator production to endotoxin in the rat. | 1995 | Shock | pmid:8608403 |
| Kritz H et al. | Isradipine increases vascular prostaglandin I2-formation while the thromboxane B2-synthesis is diminished. | 1995 | Thromb. Res. | pmid:8610276 |
| Aune B et al. | Hormone replacement therapy reduces the reactivity of monocytes and platelets in whole blood--a beneficial effect on atherogenesis and thrombus formation? | 1995 | Am. J. Obstet. Gynecol. | pmid:8610768 |
| Osterud B et al. | Effect of marine oils supplementation on coagulation and cellular activation in whole blood. | 1995 | Lipids | pmid:8614301 |
| Awni WM et al. | The pharmacokinetic and pharmacodynamic interactions between the 5-lipoxygenase inhibitor zileuton and the cyclo-oxygenase inhibitor naproxen in human volunteers. | 1995 | Clin Pharmacokinet | pmid:8620667 |
| Praticó D and FitzGerald GA | Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2. | 1996 | J. Biol. Chem. | pmid:8621535 |
| Hirashima Y et al. | Prevention of cerebrovasospasm following subarachnoid hemorrhage in rabbits by the platelet-activating factor antagonist, E5880. | 1996 | J. Neurosurg. | pmid:8622157 |
| Korn RL et al. | The effects of Carmeda Bioactive Surface on human blood components during simulated extracorporeal circulation. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8622305 |
| McAdam B et al. | Transdermal modification of platelet function: an aspirin patch system results in marked suppression of platelet cyclooxygenase. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8627531 |
| Jacoby RF et al. | Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam. | 1996 | Cancer Res. | pmid:8631000 |
| Suehiro T et al. | Thromboxane A2 in preservation-reperfusion injury: the effect of thromboxane A2 synthetase inhibitor. | 1996 | J. Surg. Res. | pmid:8632642 |
| Garvin PJ et al. | Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. | 1996 | Transplantation | pmid:8633364 |
| Thwaites BK et al. | Intravenous ketorolac tromethamine worsens platelet function during knee arthroscopy under spinal anesthesia. | 1996 | Anesth. Analg. | pmid:8638787 |
| Saji T et al. | [Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension]. | 1996 | J Cardiol | pmid:8642506 |
| Leung LK and Glauert HP | Reduction of the concentrations of prostaglandins E2 and F2alpha, and thromboxane B2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. | 1996 | Toxicol. Lett. | pmid:8644126 |
| Ikemura T et al. | KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils. | 1996 | Int. Arch. Allergy Immunol. | pmid:8645979 |
| Dehmlow C et al. | Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. | 1996 | Life Sci. | pmid:8649189 |
| Wahle KW and Peacock LI | Effects of isomeric cis and trans eighteen carbon monounsaturated fatty acids on porcine platelet function. | 1996 | Biochim. Biophys. Acta | pmid:8652649 |
| Haimovich B et al. | The FcgammaRII receptor triggers pp125FAK phosphorylation in platelets. | 1996 | J. Biol. Chem. | pmid:8663117 |
| Saitta A et al. | Effects of gallopamil on epinephrine and norepinephrine plasmatic levels and on TxB2 and beta-tg release in patients with coronary artery disease during adrenergic stimulus with cold pressor test. | 1995 Jul-Aug | Pharmacol. Res. | pmid:8668647 |
| Stein CM et al. | Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. | 1996 | Arthritis Rheum. | pmid:8670323 |
| Myers SI et al. | Regulation of eicosanoid synthesis in fibroblasts from inflamed gallbladders. | 1995 | Mol. Cell. Endocrinol. | pmid:8674862 |
| Tsunomori M et al. | 15-Hydroperoxyeicosapentaenoic acid inhibits arachidonic acid metabolism in rabbit platelets more potently than eicosapentaenoic acid. | 1996 | Biochim. Biophys. Acta | pmid:8679681 |
| Delatour P et al. | Pharmacodynamics and chiral pharmacokinetics of carprofen in calves. | 1996 | Br. Vet. J. | pmid:8680841 |
| Cervar M et al. | Altered release of endothelin-1,2 and thromboxane B2 from trophoblastic cells in pre-eclampsia. | 1996 | Eur. J. Clin. Invest. | pmid:8682152 |
| Taylor PM et al. | Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat. | 1996 | Res. Vet. Sci. | pmid:8685536 |
| Malý J et al. | Migraine--a haematological disorder? | 1995 | Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove | pmid:8685625 |
| Takase B et al. | Arachidonic acid metabolites in acute myocardial infarction. | 1996 | Angiology | pmid:8686958 |
| Jensen N et al. | Recovery of endothelial cells and prostanoid production in endothelial cell-seeded grafts. | 1996 | Eur J Vasc Endovasc Surg | pmid:8696898 |
| Nosál R et al. | The H1-histamine antagonist Dithiaden inhibits human platelets in vitro. | 1996 | Inflamm. Res. | pmid:8696916 |
| Sun B et al. | [The experimental observation on the procedure of atherosclerotic restenosis following PTCA]. | 1995 | Zhonghua Nei Ke Za Zhi | pmid:8697911 |
| Liu H et al. | [Effects of low dose aspirin on platelet function and prostaglandins metabolism in systemic and coronary circulation in patients with ischemia heart disease]. | 1995 | Zhonghua Nei Ke Za Zhi | pmid:8697924 |
| Howarth SR et al. | Role of thromboxane A2 in the vasoconstrictor response to endothelin-1, angiotensin II and 5-hydroxytryptamine in human placental vessels. | 1995 | Placenta | pmid:8710799 |
| Herrick AL et al. | Von Willebrand factor, thrombomodulin, thromboxane, beta-thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis. | 1996 | Ann. Rheum. Dis. | pmid:8712862 |
| Tishler M et al. | Salivary eicosanoid concentration in patients with Sjögren's syndrome. | 1996 | Ann. Rheum. Dis. | pmid:8712887 |
| Oláh L et al. | [Low doses of acetylsalicylic acid effectively inhibits thrombocyte aggregation after ischemic stroke]. | 1996 | Orv Hetil | pmid:8714038 |
| Kruse-Elliott KT et al. | Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist. | 1996 | Shock | pmid:8721386 |
| Yanase T et al. | Dibutyryl cAMP improves systemic vasoconstriction caused by endotoxin in dogs. | 1996 | Shock | pmid:8721389 |
| Grauer GF et al. | Effects of dietary n-3 fatty acid supplementation versus thromboxane synthetase inhibition on gentamicin-induced nephrotoxicosis in healthy male dogs. | 1996 | Am. J. Vet. Res. | pmid:8725828 |
| Isozaki H et al. | Urinary thromboxane B2 as an indicator of acute rejection in human liver transplantation. | 1996 | Surg. Today | pmid:8727944 |
| Xiong YL and Zhao HY | Effect of captopril on antithrombus function of endothelium. | 1995 | J. Tongji Med. Univ. | pmid:8731927 |
| Xiong YL and Zhao HY | Experimental studies on preventive effects of API0134 on vessel reocclusion after thrombolysis. | 1995 | J. Tongji Med. Univ. | pmid:8731957 |
| Liang XC et al. | [Study on relationship of lipid peroxide in coronary heart disease with and without diabetes]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732128 |
| Liang-min LD et al. | [Effect of age on hemostasis and plasma level of TXB2 and 6-keto-PGF1 alpha]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732148 |
| Li H | [Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation]. | 1995 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8732157 |
| Cheng Z et al. | Pharmacokinetics and pharmacodynamics of phenylbutazone and oxyphenbutazone in the donkey. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8735424 |
| Jancinová V et al. | Inhibition of blood platelet functions by cationic amphiphilic drugs in relation to their physico-chemical properties. | 1996 | Blood Coagul. Fibrinolysis | pmid:8735816 |
| Lechi C et al. | In vitro study of the anti-aggregating activity of two nitroderivatives of acetylsalicylic acid. | 1996 | Blood Coagul. Fibrinolysis | pmid:8735820 |
| Ravn HB et al. | Magnesium inhibits human platelets. | 1996 | Blood Coagul. Fibrinolysis | pmid:8735829 |