Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Santilli F et al. | Effects of high-amount-high-intensity exercise on in vivo platelet activation: modulation by lipid peroxidation and AGE/RAGE axis. | 2013 | Thromb. Haemost. | pmid:24030807 |
Kapłon-Cieślicka A et al. | Predictors of high platelet reactivity during aspirin treatment in patients with type 2 diabetes. | 2013 | Kardiol Pol | pmid:24065375 |
Jastrzębska M et al. | Factors influencing multiplate whole blood impedance platelet aggregometry measurements, during aspirin treatment in acute ischemic stroke: a pilot study. | 2013 | Blood Coagul. Fibrinolysis | pmid:24071649 |
Lv GY et al. | Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. | 2013 | J Ethnopharmacol | pmid:24080032 |
Li H et al. | Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. | 2013 | PLoS ONE | pmid:24098505 |
d'Emmanuele di Villa Bianca R et al. | Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24019484 |
Sayers BC et al. | Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23642096 |
Reyes JJ et al. | Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood. | 2013 | Eur J Nutr | pmid:22584413 |
Fox T et al. | Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis. | 2013 | Cornea | pmid:23792437 |
Borst O et al. | Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation. | 2013 | Cell. Physiol. Biochem. | pmid:23817201 |
Zhang J et al. | Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. | 2013 | J Ethnopharmacol | pmid:23685195 |
Wei XJ et al. | Effects of carboxymethylpachymaran on signal molecules in chicken immunocytes. | 2013 | Int. J. Biol. Macromol. | pmid:23664932 |
Kang JW et al. | Anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3',5'-tetramethoxy-8-O-4'-neolignan from Myristica fragrans. | 2013 | Phytother Res | pmid:23296979 |
Snider AJ et al. | Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis. | 2013 | PLoS ONE | pmid:23301082 |
Xue YT et al. | Effect of anger on endothelial-derived vasoactive factors in spontaneously hypertensive rats. | 2013 | Heart Lung Circ | pmid:23261325 |
Gao H et al. | Effects of Yerba Mate tea (Ilex paraguariensis) on vascular endothelial function and liver lipoprotein receptor gene expression in hyperlipidemic rats. | 2013 | Fitoterapia | pmid:23266732 |
Reese EA et al. | Gabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder. | 2012 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22841517 |
Olson MT et al. | Effect of assay specificity on the association of urine 11-dehydro thromboxane B2 determination with cardiovascular risk. | 2012 | J. Thromb. Haemost. | pmid:23072449 |
Jarvis GE et al. | A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). | 2012 | J. Thromb. Haemost. | pmid:22103309 |
Alizzi AM et al. | Reduction of post-surgical pericardial adhesions using a pig model. | 2012 | Heart Lung Circ | pmid:22078313 |
Hui C et al. | Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases. | 2012 | Arch. Gynecol. Obstet. | pmid:22083312 |
Hu YY et al. | Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells. | 2012 | Immunol. Invest. | pmid:22087636 |
Shoeb M and Ramana KV | Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. | 2012 | Free Radic. Biol. Med. | pmid:22067901 |
Wang Z et al. | Aspirin resistance in off-pump coronary artery bypass grafting. | 2012 | Eur J Cardiothorac Surg | pmid:21636287 |
Larsen SB et al. | Increased platelet aggregation and serum thromboxane levels in aspirin-treated patients with prior myocardial infarction. | 2012 | Thromb. Haemost. | pmid:22534977 |
Li C et al. | Reversal of the anti-platelet effects of aspirin and clopidogrel. | 2012 | J. Thromb. Haemost. | pmid:22268852 |
RodrÃguez-Vilarrupla A et al. | PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats. | 2012 | J. Hepatol. | pmid:22245887 |
Mullins KB et al. | Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. | 2012 | Vet Anaesth Analg | pmid:22248445 |
Bednar F et al. | Evaluation of aspirin's effect on platelet function early after coronary artery bypass grafting. | 2012 | J. Cardiothorac. Vasc. Anesth. | pmid:22281116 |
Cathcart CJ et al. | Lack of inhibitory effect of acetylsalicylic acid and meloxicam on whole blood platelet aggregation in cats. | 2012 | J Vet Emerg Crit Care (San Antonio) | pmid:22316324 |
Mo J et al. | Expression of interleukin-18 in a rat model of deep vein thrombosis. | 2012 | J Cardiovasc Surg (Torino) | pmid:22318348 |
Hartanto MD et al. | Urinary 11-dehydro-thromboxane Bâ‚‚ and 2,3-dinor-6-keto-prostaglandin-Fâ‚α in healthy post-menopausal and pre-menopausal women receiving aspirin 100 mg. | 2012 | J. Thromb. Thrombolysis | pmid:22311294 |
Smith JP et al. | Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. | 2012 | Hypertension | pmid:22311905 |
Brivio I et al. | The pulmonary pharmacology of [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide] (2NTX-99), an anti-atherotrombotic compound with therapeutic potential in pathological conditions that target lung vasculature. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22342851 |
Lemkes BA et al. | The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. | 2012 | J. Thromb. Haemost. | pmid:22252020 |
Matsuzawa S et al. | Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. | 2012 | Arzneimittelforschung | pmid:22945770 |
Rocca B et al. | The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes. | 2012 | J. Thromb. Haemost. | pmid:22471290 |
Lee JJ et al. | Morusinol extracted from Morus alba inhibits arterial thrombosis and modulates platelet activation for the treatment of cardiovascular disease. | 2012 | J. Atheroscler. Thromb. | pmid:22472211 |
Bruegel M et al. | Sepsis-associated changes of the arachidonic acid metabolism and their diagnostic potential in septic patients. | 2012 | Crit. Care Med. | pmid:22511130 |
Totani L et al. | Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. | 2012 | Thromb. Haemost. | pmid:22436970 |
Ajamieh H et al. | Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation. | 2012 | J. Gastroenterol. Hepatol. | pmid:22432744 |
Shatoor AS et al. | Effect of Hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino Wistar rats. | 2012 | Thromb. Res. | pmid:22261477 |
Brentnall C et al. | Potency and selectivity of carprofen enantiomers for inhibition of bovine cyclooxygenase in whole blood assays. | 2012 | Res. Vet. Sci. | pmid:22703724 |
Peters SM et al. | In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. | 2012 | Vet. Immunol. Immunopathol. | pmid:22648045 |
Zhou MT et al. | Continuous regional arterial infusion with fluorouracil and octreotide attenuates severe acute pancreatitis in a canine model. | 2012 | PLoS ONE | pmid:22655040 |
Saadawi S et al. | Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin Eâ‚‚ and Thromboxane Bâ‚‚ production and platelet activating factor receptor binding. | 2012 | Molecules | pmid:22538486 |
Sadilkova L et al. | The purification step is not crucial in EIA measurements of thromboxane B2 and 11-dehydrothromboxane B2 in human plasma. | 2012 | Clin. Lab. | pmid:22372363 |
Salama MM et al. | Resistance to low-dose aspirin therapy among patients with acute coronary syndrome in relation to associated risk factors. | 2012 | J Clin Pharm Ther | pmid:23121257 |
Yokoyama H et al. | Theoretical investigation of aspirin dosage regimen to exhibit optimal antiplatelet effects and decrease risk of upper gastrointestinal lesions. | 2012 | Biol. Pharm. Bull. | pmid:23047244 |
Liou JT et al. | Levobupivacaine differentially suppresses platelet aggregation by modulating calcium release in a dose-dependent manner. | 2012 | Acta Anaesthesiol Taiwan | pmid:23026170 |