Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Venous Thrombosis D020246 11 associated lipids
Mastocytosis D008415 5 associated lipids
Asthenia D001247 5 associated lipids
Chest Pain D002637 4 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Thrombophilia D019851 6 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Fistula D005402 8 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Varicose Veins D014648 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Macular Edema D008269 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Diseases in Twins D004200 4 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Edema, Cardiac D004489 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Yang Deficiency D016711 3 associated lipids
Bluetongue D001819 1 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Hock CE and Lefer AM Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock. 1984 Circ. Shock pmid:6542462
Ito T et al. Selective thromboxane synthetase inhibitor and ischemic heart disease. 1984 Biomed. Biochim. Acta pmid:6542777
De Clerck F et al. Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. 1984 Agents Actions pmid:6543415
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Thromb. Haemost. pmid:6495252
Stahl RA et al. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. 1984 Am. J. Physiol. pmid:6507633
Kääpä P et al. Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. 1984 Pediatr. Res. pmid:6472947
D'Angelo A et al. Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. 1984 Eur. J. Clin. Invest. pmid:6428908
Takeda H et al. [Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation]. 1984 Kyobu Geka pmid:6389949
Jackson EK et al. Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485. 1984 Life Sci. pmid:6330486
Kawai C New horizons in cardiology. 1984 Int. J. Cardiol. pmid:6334040
Hänsch GM et al. Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. 1984 J. Immunol. pmid:6432907
Brunner D et al. Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus. 1984 Clin Ther pmid:6206948
Gragnoli G et al. [Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics]. 1984 Minerva Med. pmid:6207465
Rachmilewitz D and Karmeli F Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. 1984 Eur. J. Pharmacol. pmid:6152213
Stock JL and Coderre JA Calcitonin enhances production of prostaglandins by stimulated human monocytes. 1984 Prostaglandins pmid:6087420
Yui Y et al. Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. 1984 Circulation pmid:6434196
Coker SJ and Parratt JR The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. 1984 J. Mol. Cell. Cardiol. pmid:6366241
Dembinska-Kieć A et al. Formation of leukotriene C4-like material by rat brain tissue. 1984 Eur. J. Pharmacol. pmid:6426980
Stuart MJ et al. Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. 1984 Pediatrics pmid:6435087
Kelton JG et al. A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. 1984 Thromb. Res. pmid:6740573
Schultze G et al. Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. 1984 Transplant. Proc. pmid:6592863
Morrison AR and Crowley JR Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. 1984 Arch. Biochem. Biophys. pmid:6437329
Ylikorkala O Prostanoids in gynaecology. 1984 Ann. Clin. Res. pmid:6398666
Vapaatalo H et al. Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. 1984 Ann. Clin. Res. pmid:6398981
Dahl ML and Uotila P Salicylate does not interfere with aspirin in human blood in vivo. 1984 Prostaglandins Leukot Med pmid:6585840
Oglesby TD and Gorman RR The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. 1984 Biochim. Biophys. Acta pmid:6424715
Marks JG et al. Contact urticaria and airway obstruction from carbonless copy paper. 1984 Aug 24-31 JAMA pmid:6235381
MacNab MW et al. The effects of a new thromboxane synthetase inhibitor, CGS-13080, in man. 1984 Feb-Mar J Clin Pharmacol pmid:6371062
Buchanan MR and Hirsh J Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits. 1984 Jul-Aug Arteriosclerosis pmid:6380468
Paajanen H et al. Modification of platelet aggregation and thromboxane synthesis by intravascular contrast media. 1984 Jul-Aug Invest Radiol pmid:6434489
De Caterina R et al. Thromboxane-B2 generation during ex-vivo platelet aggregation. 1984 Jul-Sep J. Nucl. Med. Allied Sci. pmid:6530623
Egg D Concentrations of prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 in synovial fluid from patients with inflammatory joint disorders and osteoarthritis. 1984 Mar-Apr Z Rheumatol pmid:6730731
Tanabe M et al. Inhibition of coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion by 2-phenylaminoadenosine (CV-1808) in anesthetized dogs. 1984 May-Jun J. Cardiovasc. Pharmacol. pmid:6202970
Laustiola K et al. Exercise-induced increase in plasma arachidonic acid and thromboxane B2 in healthy men: effect of beta-adrenergic blockade. 1984 May-Jun J. Cardiovasc. Pharmacol. pmid:6202971
Sturm M et al. The measurement of plasma thromboxane B2 and the effect of smoking. 1984 Nov-Dec Clin. Exp. Pharmacol. Physiol. pmid:6536421
Menitove JE et al. Use of prostacyclin to inhibit activation of platelets during preparation of platelet concentrates. 1984 Nov-Dec Transfusion pmid:6390814
Fisher M et al. Selective thromboxane inhibition: a new approach to antiplatelet therapy. 1984 Sep-Oct Stroke pmid:6474531
Uderman HD et al. Thromboxane synthetase inhibitor UK38,485 lowers blood pressure in the adult spontaneously hypertensive rat. 1984 Sep-Oct J. Cardiovasc. Pharmacol. pmid:6209508
Ahlsten G et al. Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. 1985 Prostaglandins Leukot Med pmid:3863152
Rosenkranz B and Frölich JC Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. 1985 Prostaglandins Leukot Med pmid:3864170
Demling RH et al. Early lung dysfunction after major burns: role of edema and vasoactive mediators. 1985 J Trauma pmid:2413227
Myśliwiec M et al. Plasma thromboxane B2 in haemodialysed patients. 1985 Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. pmid:2414174
Luzzatto G et al. PF 4 versus beta TG as evidence for platelet activation in myeloproliferative disorders. 1985 Scand J Haematol pmid:2414843
Yajima M et al. Plasma thromboxane B2, 6-keto PGF1 alpha and cyclic nucleotides levels as related to treadmill exercise test in patients with ischemic heart disease. 1985 Jpn. Circ. J. pmid:2982050
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Kobayashi H et al. Effects of 6-keto-prostaglandin E1 on ascitic hepatoma-130 in vivo comparison with chemotherapeutic agents. 1985 Prostaglandins pmid:3920729
Powell AM et al. Menstrual-PGF2 alpha, PGE2 and TXA2 in normal and dysmenorrheic women and their temporal relationship to dysmenorrhea. 1985 Prostaglandins pmid:3856904
Ylitalo P et al. Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol. 1985 Clin. Pharmacol. Ther. pmid:3899459
Berman B et al. Interferon enhancement of HLA-DR antigen expression on epidermal Langerhans cells. 1985 J. Invest. Dermatol. pmid:2578172
Patrono C et al. Clinical pharmacology of platelet cyclooxygenase inhibition. 1985 Circulation pmid:3933848
VanRollins M et al. Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. 1985 Biochim. Biophys. Acta pmid:3918572
Gee MH et al. Eicosanoids, leukocytes and lung injury. 1985 Prog. Clin. Biol. Res. pmid:3934681
Zavagli G et al. Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment. 1985 Prostaglandins Leukot Med pmid:2997804
Shono F et al. A solid-phase enzyme immunoassay of thromboxane B2. 1985 J. Biochem. pmid:3935648
Sinzinger H Double blind study of the influence of co-dergocrine on platelet parameters in healthy volunteers. 1985 Eur. J. Clin. Pharmacol. pmid:2998802
Greer IA et al. Platelet activation in allergic asthma. 1985 Thromb. Haemost. pmid:2931855
Safai-Kutti S et al. Impaired in vivo platelet reactivity in infantile autism. 1985 Acta Paediatr Scand pmid:2931944
Mikhailidis DP et al. Heparin-induced platelet aggregation in anorexia nervosa and in severe peripheral vascular disease. 1985 Eur. J. Clin. Invest. pmid:3938401
Meese CO et al. Measurement of thromboxane B2 in human urine by isotope dilution and negative ion chemical ionization mass spectrometry. 1985 Biomed. Mass Spectrom. pmid:2932184
Boss AH et al. Effect of incremental doses of aspirin on bleeding time, platelet aggregation and thromboxane production in patients with cerebrovascular disease. 1985 Eur. J. Clin. Invest. pmid:3938412
Ambler J et al. CGS 12970: a novel, long acting thromboxane synthetase inhibitor. 1985 Br. J. Pharmacol. pmid:2932197
Schambelan M et al. Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus. 1985 J. Clin. Invest. pmid:3156147
Velardo B and Lagarde M Differential effect of external calcium on the oxygenated metabolism of endogenous and exogenous arachidonic acid in platelets. 1985 Biochem. Biophys. Res. Commun. pmid:3927915
Klotman PE et al. Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats. 1985 Kidney Int. pmid:2422431
Croft KD et al. Onset of changes in phospholipid fatty acid composition and prostaglandin synthesis following dietary manipulation with n-6 and n-3 fatty acids in the rat. 1985 Biochim. Biophys. Acta pmid:3995069
Eldor A et al. Platelet interaction with subendothelial extracellular matrix: platelet-fibrinogen interactions are essential for platelet aggregation but not for the matrix-induced release reaction. 1985 Blood pmid:3995180
Moncada S and Whittle BJ Biological actions of prostacyclin and its pharmacological use in platelet studies. 1985 Adv. Exp. Med. Biol. pmid:3010671
Preud'homme Y et al. Metabolism of arachidonic acid in rabbit iris and retina. 1985 Invest. Ophthalmol. Vis. Sci. pmid:3930417
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
De Caterina R et al. Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159210
Trimarco B et al. Indomethacin blunts the late phase of nitroglycerin-induced coronary vasodilatation in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159220
Rajtar G et al. Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors. 1985 Biochem. Pharmacol. pmid:3918536
Shikano M et al. Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159226
Prosdocimi M et al. Prostacyclin and thromboxane levels during cardiac ischemia in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159235
Stine RA et al. Failure of percutaneous transluminal coronary angioplasty to stimulate platelet and prostaglandin activity. 1985 Cathet Cardiovasc Diagn pmid:3160477
Liu MC et al. Studies of platelet hyperactivity in patients with ischemic cerebrovascular diseases. III. Platelet hyperactivation in the chronic phase of cerebral thromboembolism. 1985 Taiwan Yi Xue Hui Za Zhi pmid:3160819
Hechtman DH and Jageneau A Inhibition of cold-induced vasoconstriction with ketanserin. 1985 Microvasc. Res. pmid:3160915
Elliott GR et al. Differential regulation of the cyclooxygenase pathway in starch elicited rat peritoneal macrophages by prostaglandin E2, U-44069, a stable endoperoxide analogue and dibutyryl-cyclic AMP. 1985 Eur. J. Pharmacol. pmid:2995076
Weisman SM et al. Platelet-activating factor is a potent stimulus for renal prostaglandin synthesis: possible significance in unilateral ureteral obstruction. 1985 J. Pharmacol. Exp. Ther. pmid:3862805
Bornman MS et al. Elevated thromboxane B2 levels during erection. 1985 S. Afr. Med. J. pmid:3839322
Galli C et al. Modification of brain vascular eicosanoids after pharmacological treatment and ischemia in the rat: drugs and brain vascular eicosanoids. 1985 Cephalalgia pmid:3839438
Casey LC et al. The role of thromboxane in primate endotoxin shock. 1985 J. Surg. Res. pmid:3839548
Jindal SK et al. Regulation of increase in anastomotic blood flow following pulmonary arterial occlusion. 1985 J. Appl. Physiol. pmid:3839787
Narita H et al. Insufficient mobilization of calcium by early breakdown of phosphatidylinositol 4,5-bisphosphate for aggregation of human platelets by collagen. 1985 J. Biochem. pmid:3001036
Garrett RC and Thomas HM Relation of prostanoids to strength of hypoxic vasoconstriction in dogs with lobar atelectasis. 1985 J. Appl. Physiol. pmid:3839788
Horiuchi Y et al. [Studies on changes in histamine levels in the blood of infants and children. Part 7. The time studies of histamine, lipoxygenase metabolites, thromboxe B2 and cyclic AMP release from human platelets and leucocytes on treadmill exercise in asthmatic children]. 1985 Arerugi pmid:3002304
Giani E et al. Heated fat, vitamin E and vascular eicosanoids. 1985 Lipids pmid:3839887
Steinhauer HB et al. Stimulation of peritoneal synthesis of vasoactive prostaglandins during peritonitis in patients on continuous ambulatory peritoneal dialysis. 1985 Eur. J. Clin. Invest. pmid:3921379
DiMinno G et al. Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane. 1985 Blood pmid:2981130
Gairola C and Tai HH Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency. 1985 Biochem. Biophys. Res. Commun. pmid:2998361
Wong C et al. Effect of hydroxyl radical scavenging on endotoxin-induced lung injury. 1985 Surgery pmid:2983450
Jackson EK Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesentery. 1985 J. Clin. Invest. pmid:4077980
Dempsey RJ et al. Polyamine and prostaglandin markers in focal cerebral ischemia. 1985 Neurosurgery pmid:3864030
De Caterina R et al. Equal antiplatelet effects of aspirin 50 or 324 mg/day in patients after acute myocardial infarction. 1985 Thromb. Haemost. pmid:4082090
Delvos U et al. Direct radioimmunological measurement of thromboxane B2 in plasma. 1985 Thromb. Res. pmid:4082109
Semrad SD et al. Flunixin meglumine given in small doses: pharmacokinetics and prostaglandin inhibition in healthy horses. 1985 Am. J. Vet. Res. pmid:4083579
Ding YA et al. Potentiation of adrenaline-induced platelet aggregation by angiotensin II. 1985 Thromb. Haemost. pmid:4089801
Lawson JA et al. Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography--negative-ion chemical ionization mass spectrometry. 1985 Anal. Biochem. pmid:4091270
Salmon JA et al. Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase. 1985 Prostaglandins pmid:2988019
Hutchison AA et al. Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates. 1985 Prostaglandins Leukot Med pmid:3859877