Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Greer IA et al. | Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists. | 1985 | Prostaglandins Leukot Med | pmid:2865745 |
| Mikhailidis DP et al. | The effect of non-specific beta-blockade on metabolic and haemostatic variables during hypoglycaemia. | 1985 | Diabetes Res. | pmid:2866057 |
| Mehta J et al. | Increase in human platelet alpha 2-adrenergic receptor affinity for agonist in unstable angina. | 1985 | J. Lab. Clin. Med. | pmid:2866219 |
| Greer IA et al. | A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation. | 1985 | Thromb. Haemost. | pmid:2867620 |
| Gragnoli G et al. | Effects of somatostatin on the behaviour of thromboxane B2 and beta-thromboglobulin in type I diabetes. | 1985 | Acta Endocrinol. | pmid:2408435 |
| Yardumian DA et al. | Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374. | 1985 | Br. J. Haematol. | pmid:2408653 |
| Patrassi GM et al. | Contact phase of coagulation in diabetes mellitus after aspirin administration. | 1985 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2410343 |
| Brown EM and Swartz SL | Production of prostaglandins by dispersed cells and fragments from bovine parathyroid glands. | 1985 | Prostaglandins | pmid:3883430 |
| Boraschi D et al. | Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons. | 1985 | J. Immunol. | pmid:3923110 |
| Walsh SW | Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. | 1985 | Am. J. Obstet. Gynecol. | pmid:3923838 |
| Stenmark KR et al. | Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. | 1985 | Am. J. Physiol. | pmid:3923843 |
| Jakubowski JA et al. | Cumulative antiplatelet effect of low-dose enteric coated aspirin. | 1985 | Br. J. Haematol. | pmid:3927970 |
| Mehta J et al. | Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides. | 1985 | J. Lab. Clin. Med. | pmid:3928780 |
| Sawada M et al. | Enzyme-immunoassay of thromboxane B2 at the picogram level. | 1985 | Prostaglandins | pmid:3929333 |
| De Caterina R et al. | Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. | 1985 | Eur. Heart J. | pmid:3930246 |
| Mehta P et al. | Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors. | 1985 | Am J Pediatr Hematol Oncol | pmid:2994511 |
| Benigni A et al. | Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated? | 1985 | Am. J. Nephrol. | pmid:2996352 |
| Wenger H et al. | Pulmonary dysfunction secondary to soft-tissue endotoxin. | 1985 | Arch Surg | pmid:3883949 |
| Meyrick B et al. | Endothelial prostacyclin production is a late event in granulocyte migration into bovine pulmonary artery intimal explants. | 1985 | Blood | pmid:3904871 |
| Kubo K and Kobayashi T | Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. | 1985 | Am. Rev. Respir. Dis. | pmid:3898941 |
| Barst RJ and Stalcup SA | Endothelial function in clinical pulmonary hypertension. | 1985 | Chest | pmid:3899537 |
| Pedersen AK and FitzGerald GA | Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing. | 1985 | Clin. Pharmacol. Ther. | pmid:3917387 |
| Pediconi M et al. | Effects of acute and chronic ethanol administration on thromboxane and prostacyclin levels and release in rat brain cortex. | 1985 | Prostaglandins | pmid:3901122 |
| Neri Serneri GG et al. | Abnormal cardiocoronary thromboxane A2 production in patients with unstable angina. | 1985 | Am. Heart J. | pmid:3984828 |
| Barst RJ et al. | Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child. | 1985 | Am. Rev. Respir. Dis. | pmid:3917630 |
| Halenda SP et al. | Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187. | 1985 | J. Biol. Chem. | pmid:3930496 |
| Zahavi J and Zahavi M | Enhanced platelet release reaction, shortened platelet survival time and increased platelet aggregation and plasma thromboxane B2 in chronic obstructive arterial disease. | 1985 | Thromb. Haemost. | pmid:3158092 |
| Roy L et al. | Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease. | 1985 | Am. Heart J. | pmid:3158183 |
| Patterson GA et al. | Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs. | 1985 | J. Appl. Physiol. | pmid:3884582 |
| Valentovic MA and Lubawy WC | Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. | 1985 | Prostaglandins Leukot Med | pmid:3903777 |
| Bergqvist D et al. | The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. | 1985 | Thromb. Res. | pmid:3838828 |
| Stuart MJ et al. | Prostanoids in hemolytic uremic syndrome. | 1985 | J. Pediatr. | pmid:3839015 |
| Nigam S et al. | The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast. | 1985 | Prostaglandins | pmid:3839084 |
| Petroni A et al. | Differential effects of various vasoactive drugs on basal and stimulated levels of TXB2 and 6-keto-PGF1 alpha in rat brain. | 1985 | Prostaglandins | pmid:3839085 |
| Mendieta CF et al. | Biosynthesis of prostaglandins in gingiva of patients with chronic periodontitis. | 1985 | J. Periodontol. | pmid:3919173 |
| Haurand M and Ullrich V | Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. | 1985 | J. Biol. Chem. | pmid:2999104 |
| Hillbom M et al. | Platelet thromboxane formation and bleeding time is influenced by ethanol withdrawal but not by cigarette smoking. | 1985 | Thromb. Haemost. | pmid:4049313 |
| Aviram M et al. | Plasma lipoproteins affect platelet malondialdehyde and thromboxane B2 production. | 1985 | Biochem Med | pmid:4052061 |
| Rinaldo JE and Dauber JH | Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia. | 1985 | Circ. Shock | pmid:4053294 |
| Leffler CW and Busija DW | Prostanoids in cortical subarachnoid cerebrospinal fluid and pial arterial diameter in newborn pigs. | 1985 | Circ. Res. | pmid:4053302 |
| Shohami E and Gross J | An ex vivo method for evaluating prostaglandin synthetase activity in cortical slices of mouse brain. | 1985 | J. Neurochem. | pmid:3923156 |
| Tobian L et al. | Prostaglandin alterations in barely hypertensive Dahl S rats. | 1985 | Trans. Assoc. Am. Physicians | pmid:3842205 |
| Numano F et al. | Coronary spasm, prostaglandin and HLA factors. | 1985 | Jpn. Circ. J. | pmid:3855470 |
| Purkerson ML et al. | Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3855542 |
| Dahl ML and Uotila P | Sodium salicylate does not prevent the inhibitory effect of indomethacin on thromboxane formation in human blood ex vivo. | 1985 | Prostaglandins Leukot Med | pmid:3856282 |
| Miura K et al. | Effect of SA-446, an angiotensin-converting enzyme inhibitor, on renal function in anesthetized dogs: special reference to arachidonic acid metabolites. | 1985 Jan-Feb | J. Cardiovasc. Pharmacol. | pmid:2580127 |
| Olanoff LS et al. | Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia. | 1985 Jan-Feb | J. Cardiovasc. Pharmacol. | pmid:2580129 |
| Hook BG et al. | Experimental coronary artery thrombosis in the absence of thromboxane A2 synthesis: evidence for alternate pathways for coronary thrombosis. | 1985 Jan-Feb | J. Cardiovasc. Pharmacol. | pmid:2580139 |
| Fisher M and Zipser R | Increased excretion of immunoreactive thromboxane B2 in cerebral ischemia. | 1985 Jan-Feb | Stroke | pmid:3966251 |
| Mullane KM and McGiff JC | Platelet depletion and infarct size in an occlusion-reperfusion model of myocardial ischemia in anesthetized dogs. | 1985 Jul-Aug | J. Cardiovasc. Pharmacol. | pmid:2410715 |
| Uyama O et al. | The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in patients with ischemic cerebrovascular disease. | 1985 Mar-Apr | Stroke | pmid:3883580 |
| Fujimoto T et al. | Cerebrovascular injuries induced by activation of platelets in vivo. | 1985 Mar-Apr | Stroke | pmid:3975962 |
| Lamy M et al. | Biochemical pathways of acute lung injury. | 1985 May-Jun | Bull Eur Physiopathol Respir | pmid:3873973 |
| Jolly SR et al. | Platelet depletion in experimental myocardial infarction. | 1985 May-Jun | Basic Res. Cardiol. | pmid:4026785 |
| Hillbom M et al. | Effects of ethanol on platelet function. | 1985 May-Jun | Alcohol | pmid:4026960 |
| Codde JP et al. | Changes in prostanoid synthesis in response to diet and hypertension in one-kidney, one clip rats. | 1985 Nov-Dec | Hypertension | pmid:3908314 |
| Nagatsuka K et al. | A new approach to antithrombotic therapy--evaluation of combined therapy of thromboxane synthetase inhibitor and very low dose of aspirin. | 1985 Sep-Oct | Stroke | pmid:3931302 |
| Hughes RD et al. | 9 beta-methylcarbacyclin, a stable prostacyclin analogue, in prevention of platelet losses during charcoal haemoperfusion. | 1986 | J. Pharm. Pharmacol. | pmid:2869131 |
| Uraemic platelets. | 1986 | Lancet | pmid:2870380 | |
| Roberts MS et al. | Slow-release aspirin and prostaglandin inhibition. | 1986 | Lancet | pmid:2871403 |
| Numano F et al. | Antiaggregative aspirin dosage at the affected vessel wall. | 1986 | Angiology | pmid:2876664 |
| Reilly IA et al. | Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. | 1986 | Circulation | pmid:2938849 |
| Bolton C et al. | A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis. | 1986 | J. Neuroimmunol. | pmid:3455693 |
| Ylikorkala O et al. | Fetal and neonatal prostacyclin and thromboxane in relation to mode of delivery. | 1986 | Arch. Dis. Child. | pmid:3527082 |
| Mäkilä UM et al. | Placental thromboxane and prostacyclin in the regulation of placental blood flow. | 1986 | Obstet Gynecol | pmid:3528955 |
| Laekeman GM et al. | Prostacyclin and thromboxane in benign and malignant breast tumours. | 1986 | Br. J. Cancer | pmid:3530307 |
| Kim RB et al. | Effects of indomethacin on furosemide induced renal prostaglandin synthesis and action in man. | 1986 | Clin Invest Med | pmid:3530574 |
| Bartolini G et al. | Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system. | 1986 | Biochim. Biophys. Acta | pmid:3085720 |
| Chacho KJ et al. | Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay. | 1986 | Am. J. Obstet. Gynecol. | pmid:2940869 |
| Küster LJ et al. | Mechanism of PAF-induced platelet aggregation in man. | 1986 | Thromb. Res. | pmid:3764802 |
| Sadovskaia VL et al. | [Study of prostaglandins and thromboxanes B2 using mass-spectrometry of secondary ions]. | 1986 | Bioorg. Khim. | pmid:3768052 |
| Lelcuk S et al. | Nicotine stimulates pulmonary parenchymal thromboxane synthesis. | 1986 | Surgery | pmid:3775653 |
| Fang YX et al. | Beneficial changes in prostacyclin and thromboxane A2 induced by ginsenosides in myocardial infarction and reperfusion injury in dogs. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2954367 |
| Carrico CJ et al. | Multiple-organ-failure syndrome. | 1986 | Arch Surg | pmid:3484944 |
| Conti P et al. | Augmentation of thromboxane production in vitro by polymorphonuclears and macrophages exposed to IL1/LP. | 1986 | Agents Actions | pmid:3485895 |
| Marasini B et al. | Cigarette smoking and platelet function. | 1986 | Thromb. Res. | pmid:3787563 |
| Matsuo T et al. | A new thrombin inhibitor MD805 and thrombocytopenia encountered with heparin hemodialysis. | 1986 | Thromb. Res. | pmid:3787568 |
| Shibamoto T and Kobayashi T | Acute effect of paraquat on lung fluid balance and prostanoid production in awake sheep. | 1986 | Am. Rev. Respir. Dis. | pmid:3789525 |
| DeCampli WM et al. | Pharmacological, hematological, and physiological effects of a new thromboxane synthetase inhibitor (CGS-13080) during cardiopulmonary bypass in dogs. | 1986 | Ann. Thorac. Surg. | pmid:3789860 |
| Ahmed T et al. | Endotoxin-induced changes in pulmonary hemodynamics and respiratory mechanics. Role of lipoxygenase and cyclooxygenase products. | 1986 | Am. Rev. Respir. Dis. | pmid:3098146 |
| Carey F and Haworth D | Thromboxane synthase inhibition: implications for prostaglandin endoperoxide metabolism. II. Testing the 'redirection hypothesis' in an acute intravenous challenge model. | 1986 | Prostaglandins | pmid:3754057 |
| Zadoff AD et al. | Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep. | 1986 | J. Appl. Physiol. | pmid:3754554 |
| Arima T et al. | [Synthesis of prostaglandins (TXB2 and 6-keto-PGF1 alpha) during cardiopulmonary bypass]. | 1986 | Masui | pmid:3754591 |
| Panchenko EP et al. | [Thromboxane and prostacyclin in patients with stenocardia in induced and spontaneous ischemia of the myocardium]. | 1986 | Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR | pmid:3754753 |
| Shohami E and Gross J | Effects of hypoxia and anoxia on the ex vivo release of prostaglandins from mouse cortical slices. | 1986 | J. Neurochem. | pmid:3464697 |
| Loo MH et al. | Effect of thromboxane inhibition on renal blood flow in dogs with complete unilateral ureteral obstruction. | 1986 | J. Urol. | pmid:3464764 |
| Yardumian DA et al. | Platelet function studies during and after infusions of ZK 36374, a stable prostacyclin analogue, to healthy volunteers. | 1986 | Haemostasis | pmid:2422095 |
| Hartung HP et al. | Substance P: binding properties and studies on cellular responses in guinea pig macrophages. | 1986 | J. Immunol. | pmid:2422264 |
| Craig-Schmidt MC et al. | The essential fatty acid deficient chicken as a model for cystic fibrosis. | 1986 | Am. J. Clin. Nutr. | pmid:3466523 |
| Fareed J et al. | Molecular markers of hemostatic activation in atherosclerosis: a new concept in diagnostic profiling of endogenous pathophysiologic transition. | 1986 | Semin. Thromb. Hemost. | pmid:2943019 |
| Kudo K et al. | Urinary excretion of TXB2 after angiotensin converting enzyme inhibition in hypertensive patients. | 1986 | Prostaglandins Leukot Med | pmid:3006084 |
| Addonizio VP et al. | Effects of verapamil and diltiazem on human platelet function. | 1986 | Am. J. Physiol. | pmid:3006516 |
| Uehara S et al. | Effects of the calcium antagonist nifedipine on thromboxane B2 level and platelet aggregation in hypertensive patients. | 1986 | Arzneimittelforschung | pmid:3814228 |
| Karmali RA et al. | Eicosanoids and metastasis: experimental aspects in Lewis lung carcinoma. | 1986 | Cancer Biochem. Biophys. | pmid:3815323 |
| Säynävälammi P et al. | Inhibition of angiotensin-converting enzyme with quinapril (CI-906): investigation of antihypertensive mechanisms in spontaneously hypertensive rats. | 1986 | J. Pharmacol. Exp. Ther. | pmid:3007740 |
| Ogletree ML et al. | Influence of steroidal and nonsteroidal anti-inflammatory agents on the accumulation of arachidonic acid metabolites in plasma and lung lymph after endotoxemia in awake sheep. Measurements of prostacyclin and thromboxane metabolites and 12-HETE. | 1986 | Am. Rev. Respir. Dis. | pmid:3079978 |
| Bloom A et al. | Evidence against a platelet cyclooxygenase defect in uraemic subjects on chronic haemodialysis. | 1986 | Br. J. Haematol. | pmid:3080018 |
| Al-Hassan JM et al. | Vasoconstrictor components in the Arabian Gulf catfish (Arius thalassinus, Ruppell) proteinaceous skin secretion. | 1986 | Toxicon | pmid:3824400 |
| Hoult JR et al. | Failure of anti-inflammatory steroids to inhibit prostaglandin release from the hydronephrotic rabbit kidney. | 1986 | Agents Actions | pmid:3962772 |
| Guarner C et al. | Renal prostaglandins in cirrhosis of the liver. | 1986 | Clin. Sci. | pmid:3516533 |