Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Serebruany VL et al. | Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor? | 1997 | Mol. Aspects Med. | pmid:9266521 |
Chang TS et al. | Thromboxane A2 synthase inhibition and thromboxane A2 receptor blockade by 2-[(4-cyanophenyl)amino]-3-chloro-1,4-naphthalenedione (NQ-Y15) in rat platelets. | 1997 | Biochem. Pharmacol. | pmid:9271330 |
Azevedo I et al. | Increased spontaneous release of tumour necrosis factor-alpha by alveolar macrophages from wheezy infants. | 1997 | Eur. Respir. J. | pmid:9272917 |
Ku K et al. | Influences of dietary omega-3 polyunsaturated fatty acids on the recovery of cardiac and renal functions after preservation in hyperlipidemic rats. | 1997 | Transplantation | pmid:9275102 |
Xing X and Xia S | [The injury of liver sinusoidal endothelial cells in a rat's isolated liver perfusion (ILP) model for regional chemotherapy]. | 1996 | Zhonghua Wai Ke Za Zhi | pmid:9275689 |
Lewis K et al. | Effect of neuropeptide Y on bradykinin-induced release of prostacyclin and thromboxane from guinea pig perfused lung. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9276148 |
Berg J et al. | Isoenzyme-specific cyclooxygenase inhibitors: a whole cell assay system using the human erythroleukemic cell line HEL and the human monocytic cell line Mono Mac 6. | 1997 | J Pharmacol Toxicol Methods | pmid:9279772 |
Freese R and Mutanen M | Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. | 1997 | Am. J. Clin. Nutr. | pmid:9280178 |
Santillan-Doherty P et al. | Plasma thromboxane B2 concentrations and pulmonary vascular resistance during lung reperfusion. | 1997 Jul-Aug | J Invest Surg | pmid:9284000 |
Cipollone F et al. | Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina. | 1997 | Circulation | pmid:9286937 |
Trang LE et al. | Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. | 1977 | Scand. J. Rheumatol. | pmid:929121 |
Abate A et al. | Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. | 1997 | Inflamm. Res. | pmid:9297549 |
Tanaka M et al. | Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats. | 1997 | Biol. Neonate | pmid:9303217 |
Berlin I et al. | [Comparison between effects of morning and evening administration of effervescent calcium carbasalate (equivalent of 160 mg aspirin) on the gastroduodenal mucosa in healthy volunteers]. | 1997 | Pathol. Biol. | pmid:9309270 |
Swails WS et al. | Effect of a fish oil structured lipid-based diet on prostaglandin release from mononuclear cells in cancer patients after surgery. | 1997 Sep-Oct | JPEN J Parenter Enteral Nutr | pmid:9323688 |
Uteshev DB and Uteshev BS | [Adhesive molecules as drugs and objects of pharmacological effect in myocardial ischemia and reperfusion]. | 1997 May-Jun | Eksp Klin Farmakol | pmid:9324410 |
Moser L et al. | ACE inhibitor effects on platelet function in stages I-II hypertension. | 1997 | J. Cardiovasc. Pharmacol. | pmid:9335405 |
Matrougui K et al. | Impaired nitric oxide- and prostaglandin-mediated responses to flow in resistance arteries of hypertensive rats. | 1997 | Hypertension | pmid:9336397 |
Hashimoto Y et al. | Characteristics of protein kinase C-independent exocytosis in human platelets. | 1997 | Thromb. Res. | pmid:9336873 |
Chavali SR et al. | Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. | 1997 | Int. Arch. Allergy Immunol. | pmid:9338609 |