Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Venous Thrombosis D020246 11 associated lipids
Mastocytosis D008415 5 associated lipids
Asthenia D001247 5 associated lipids
Chest Pain D002637 4 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Thrombophilia D019851 6 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Fistula D005402 8 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Varicose Veins D014648 7 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Macular Edema D008269 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Diseases in Twins D004200 4 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Edema, Cardiac D004489 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Yang Deficiency D016711 3 associated lipids
Bluetongue D001819 1 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Drowning D004332 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Radiculopathy D011843 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Durando MM et al. Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization. 1998 J. Leukoc. Biol. pmid:9715266
Hsiao G et al. Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb. 1998 Biol. Pharm. Bull. pmid:9703250
Ingster LM and Feinleib M Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. 1998 Am J Public Health pmid:9702172
Iida T et al. The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats. 1998 Pancreas pmid:9700944
Fagugli RM et al. Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. 1998 Clin. Nephrol. pmid:9696430
Levy M et al. Cerebrospinal fluid prostaglandins after systemic dipyrone intake. 1998 Clin. Pharmacol. Ther. pmid:9695726
Murphy NP et al. Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. 1998 J. Pharmacol. Exp. Ther. pmid:9694954
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Lebel B et al. Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. 1998 Int. Arch. Allergy Immunol. pmid:9693278
Napoli E and Franco N [Thromboxane A2 production in the pathogenesis of diabetic complications]. 1998 Minerva Endocrinol. pmid:9691631
Bell JG et al. Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9690713
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Tewes KS et al. Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. 1998 Anal. Biochem. pmid:9683522
De La Cruz JP et al. Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. 1998 Eur. J. Pharmacol. pmid:9683018
Onizuka M et al. Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). 1998 Surg. Today pmid:9681611
Cheng Z et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. 1998 Inflammation pmid:9675607
Miyamoto A et al. The role of thromboxane A2 in regulating porcine basilar arterial tone. 1998 J. Vet. Pharmacol. Ther. pmid:9673964
Sheu JR et al. Inhibitory mechanisms of naloxone on human platelets. 1998 Jul-Aug Clin. Exp. Pharmacol. Physiol. pmid:9673433
Kunitoh H et al. A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. 1998 J Asthma pmid:9669829
Geertsen PF et al. Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. 1998 Clin. Sci. pmid:9662488