Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypercapnia D006935 5 associated lipids
Asthenia D001247 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Snapper JR et al. Effects of platelet depletion on the unanesthetized sheep's pulmonary response to endotoxemia. 1984 J. Clin. Invest. pmid:6501570
Giani E et al. Sex differences in platelet thromboxane and arterial prostacyclin production in control and n-6 fatty acid supplemented rats. 1984 Prostaglandins pmid:6441187
Chan PK and Gentry PA Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol. 1984 Food Chem. Toxicol. pmid:6540739
Moufarrij NA et al. Thromboxane synthetase inhibition in acute focal cerebral ischemia in cats. 1984 J. Neurosurg. pmid:6542131
Hock CE and Lefer AM Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock. 1984 Circ. Shock pmid:6542462
Katz JM et al. Inhibition of prostaglandin action and bone resorption by copper. 1984 Ann. Rheum. Dis. pmid:6441529
Ito T et al. Selective thromboxane synthetase inhibitor and ischemic heart disease. 1984 Biomed. Biochim. Acta pmid:6542777
De Clerck F et al. Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. 1984 Agents Actions pmid:6543415
Menys VC and Davies JA Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben). 1984 Lab. Invest. pmid:6546403
Pedersen AK et al. Inhibition of thromboxane biosynthesis in serum: limitations of the measurement of immunoreactive 6-keto-PGF1 alpha. 1984 Thromb. Res. pmid:6546456
Krishnamurthi S et al. Regulation of human platelet activation--analysis of cyclooxygenase and cyclic AMP-dependent pathways. 1984 Biochem. Pharmacol. pmid:6091666
Novo S et al. Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs. 1984 Adv. Exp. Med. Biol. pmid:6546467
Ford WD et al. Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations. 1984 Arch. Dis. Child. pmid:6546658
Rosenblum WI and Hirsh PD Some interrelationships between glucose levels thromboxane production and prostacyclin production in normal and diabetic mice. 1984 Prostaglandins pmid:6546804
Le Breton GC et al. 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone: a potent inhibitor of the blood platelet cyclo-oxygenase. 1984 Prostaglandins pmid:6427851
Saldeen P et al. Thromboxane production in umbilical vein grafts. 1984 Thromb. Res. pmid:6546814
Schwartz D et al. Renal arachidonic acid metabolism and cellular changes in the rabbit renal vein constricted kidney: inflammation as a common process in renal injury models. 1984 Prostaglandins pmid:6427853
Bush LR et al. Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries. 1984 Circulation pmid:6546902
Mitsuhashi N and Kato J Bioconversion of arachidonic acid to prostaglandins and related compounds in human myometrium and uterine cervix. 1984 Endocrinol. Jpn. pmid:6442700
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Benedetto C et al. Production of prostacyclin, 6-keto-PGF1 alpha and thromboxane B2 by incubated samples of umbilical vessels: a comparison of methods for expressing the results on dry weight, wet weight, protein or DNA bases. 1984 Prostaglandins pmid:6390522
Heinonen PK and Metsä-Ketelä T Prostaglandin and thromboxane production in ovarian cancer tissue. 1984 Gynecol. Obstet. Invest. pmid:6396175
Chen LS et al. Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension. 1984 Jpn Heart J pmid:6549401
Ishihara Y et al. [Cigarette smoking and lung metabolism--effect of cigarette smoking on blood levels of 6-keto PGF1 alpha, thromboxane B2 and lipoperoxide in healthy volunteers]. 1984 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6549510
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Thromb. Haemost. pmid:6495252
Stahl RA et al. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. 1984 Am. J. Physiol. pmid:6507633
Kääpä P et al. Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. 1984 Pediatr. Res. pmid:6472947
Gachályi B et al. In vitro effect of cimetidine on ADP induced platelet aggregation and thromboxane A2 synthesis in man. 1984 Thromb. Res. pmid:6474407
Brown CG and Poyser NL Studies on ovarian prostaglandin production in relation to ovulation in the rat. 1984 J. Reprod. Fertil. pmid:6595406
Fitzpatrick F et al. Development of a gas chromatographic-mass spectrometric method using a stable isotope internal standard for quantitation of thromboxane B2. 1984 Thromb. Res. pmid:6474413
Mitrovic D et al. Anti-inflammatory drugs, prostanoid and proteoglycan production by cultured bovine articular chondrocytes. 1984 Prostaglandins pmid:6595718
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Tohoku J. Exp. Med. pmid:6474447
Prinz RA et al. Platelet activation by human pancreatic fluid. 1984 J. Surg. Res. pmid:6482425
Wilson L and Huang LS Temporal response of uterine prostaglandins to estradiol treatment in the ovariectomized-pregnant rat. 1984 Prostaglandins pmid:6484214
Walinsky P et al. Thromboxane A2 in acute myocardial infarction. 1984 Am. Heart J. pmid:6485997
D'Angelo A et al. Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. 1984 Eur. J. Clin. Invest. pmid:6428908
Baughman RP et al. Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis. 1984 Am. Rev. Respir. Dis. pmid:6388445
Ninnemann JL and Stockland AE Participation of prostaglandin E in immunosuppression following thermal injury. 1984 J Trauma pmid:6231383
DiSesa VJ et al. Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization. 1984 Ann. Thorac. Surg. pmid:6388516
Sekiya K and Okuda H Inhibitory action of soluble elastin on thromboxane B2 formation in blood platelets. 1984 Biochim. Biophys. Acta pmid:6320905
Takeda H et al. [Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation]. 1984 Kyobu Geka pmid:6389949
Olanoff LS et al. Effects of oleic acid on pulmonary capillary leak and thromboxanes. 1984 J. Surg. Res. pmid:6233456
Jackson EK et al. Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485. 1984 Life Sci. pmid:6330486
Hartung HP et al. Release of prostaglandin E and thromboxane from macrophages by stimulation with factor H. 1984 Clin. Exp. Immunol. pmid:6234114
Uotila P et al. Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. 1984 Prostaglandins pmid:6335260
Kawai C New horizons in cardiology. 1984 Int. J. Cardiol. pmid:6334040
Hänsch GM et al. Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. 1984 J. Immunol. pmid:6432907
Robson MC et al. A new explanation for the progressive tissue loss in electrical injuries. 1984 Plast. Reconstr. Surg. pmid:6422484
Huang HC Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom. 1984 Toxicon pmid:6206608
Brunner D et al. Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus. 1984 Clin Ther pmid:6206948
Gragnoli G et al. [Effects of ticlopidine on the plasma levels of beta-thromboglobulin and thromboxane B2 in types 1 and 2 diabetics]. 1984 Minerva Med. pmid:6207465
Rachmilewitz D and Karmeli F Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. 1984 Eur. J. Pharmacol. pmid:6152213
Stock JL and Coderre JA Calcitonin enhances production of prostaglandins by stimulated human monocytes. 1984 Prostaglandins pmid:6087420
Triolo G et al. Circulating immune complexes and platelet thromboxane synthesis in patients with insulin-dependent (type I) diabetes mellitus. 1984 Diabetes pmid:6611280
Yui Y et al. Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. 1984 Circulation pmid:6434196
Lee EC et al. Functional responses of tumor cells to phorbol esters: role for prostaglandins. 1984 Oncology pmid:6587276
Coker SJ and Parratt JR The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. 1984 J. Mol. Cell. Cardiol. pmid:6366241
Salmon JA et al. Benoxaprofen does not inhibit formation of leukotriene B4 in a model of acute inflammation. 1984 Biochem. Pharmacol. pmid:6089840
Alster P and Wennmalm A Effect of nicotine on the formation of prostacyclin-like activity and thromboxane in rabbit aorta and platelets. 1984 Br. J. Pharmacol. pmid:6367870
Girotti MJ et al. Effects of immunization on cardiopulmonary alterations of gram-negative endotoxemia. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6368499
Dembinska-Kieć A et al. Formation of leukotriene C4-like material by rat brain tissue. 1984 Eur. J. Pharmacol. pmid:6426980
Stuart MJ et al. Differences in thromboxane production between neonatal and adult platelets in response to arachidonic acid and epinephrine. 1984 Pediatr. Res. pmid:6435080
Stuart MJ et al. Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. 1984 Pediatrics pmid:6435087
Pan IQ et al. Alteration of platelet responses to metabolites of arachidonic acid by oral contraceptives. 1984 Br. J. Haematol. pmid:6089860
Serhan CN et al. Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. 1984 Prostaglandins pmid:6328582
Shohami E and Sidi A Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation. 1984 J. Cereb. Blood Flow Metab. pmid:6363432
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by capillary gas chromatography and negative ion chemical ionization mass spectrometry. 1984 J. Chromatogr. pmid:6736155
Kelton JG et al. A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. 1984 Thromb. Res. pmid:6740573
Schultze G et al. Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. 1984 Transplant. Proc. pmid:6592863
Zipser RD et al. Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome. 1984 Gastroenterology pmid:6593268
Koskimies AI et al. Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility. 1984 Acta Obstet Gynecol Scand Suppl pmid:6594012
Branski D et al. Prostaglandins in small intestinal mucosa of children with celiac disease. 1984 J. Pediatr. Gastroenterol. Nutr. pmid:6594493
Woodcock BE et al. The platelet defect in acute myeloid leukaemia. 1984 J. Clin. Pathol. pmid:6595273
Ogushi F et al. [In vitro release of arachidonate metabolites by human alveolar macrophages]. 1984 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6595434
Bommer J et al. Plastic filing from dialysis tubing induces prostanoid release from macrophages. 1984 Kidney Int. pmid:6595463
Brandt R et al. Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. 1984 Prostaglandins Leukot Med pmid:6597450
Chiba S et al. Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. 1984 Prostaglandins Leukot Med pmid:6597456
Holgate ST and Robinson C 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-Prostaglandin I1, (U-60,257) stimulates prostaglandin D2 and inhibits thromboxane B2 release from ionophore challenged human dispersed lung cells. 1984 Br. J. Pharmacol. pmid:6439267
Morrison AR and Crowley JR Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. 1984 Arch. Biochem. Biophys. pmid:6437329
Holgate ST et al. Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release. 1984 J. Immunol. pmid:6206153
Takeda H et al. [Alternations in coagulation and fibrinolysis associated with extracorporeal circulation--the role of vasoactive prostanoids]. 1984 Rinsho Kyobu Geka pmid:6395300
Tada M et al. Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery. 1984 J. Mol. Cell. Cardiol. pmid:6398370
Ylikorkala O Prostanoids in gynaecology. 1984 Ann. Clin. Res. pmid:6398666
DeRubertis FR et al. Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products. 1984 J. Clin. Invest. pmid:6438153
Vapaatalo H et al. Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. 1984 Ann. Clin. Res. pmid:6398981
Wang JP et al. XC 386: a new antiplatelet agent. 1984 Thromb. Res. pmid:6438827
Axelrod L and Cornelius P Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade. 1984 Prostaglandins pmid:6440213
Zimmermann I et al. [Influence of vagus nerve, histamine, prostaglandin and catecholamine on airway obstruction]. 1984 Respiration pmid:6473921
Chan CC et al. Inhibition of prostanoid-mediated platelet aggregation in vivo and in vitro by 3-hydroxymethyl-dibenzo(b,f)thiepin 5,5-dioxide (L-640,035). 1984 J. Pharmacol. Exp. Ther. pmid:6423813
Dahl ML and Uotila P Salicylate does not interfere with aspirin in human blood in vivo. 1984 Prostaglandins Leukot Med pmid:6585840
Dahl ML and Uotila P Thromboxane formation during blood clotting is decreased by verapamil. 1984 Prostaglandins Leukot Med pmid:6585842
Higgins AJ and Lees P Arachidonic acid metabolites in carrageenin-induced equine inflammatory exudate. 1984 J. Vet. Pharmacol. Ther. pmid:6423835
Hall ER et al. The reduction of potential TXB2 levels when serum is preincubated at room temperature. 1984 Prostaglandins Leukot Med pmid:6585846
Codde JP et al. Validation of the direct radioimmunoassay of prostanoids in serum and kidney. 1984 Prostaglandins Leukot Med pmid:6587406
Shaala S et al. Local effect of thromboxane B2 on the contractility of the human non pregnant uterus. 1984 Prostaglandins Leukot Med pmid:6587408
Higgins AJ et al. Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate. 1984 Cornell Vet pmid:6587959
Meydani M et al. Effects of dietary methionine, methylmercury, and atrazine on ex-vivo synthesis of prostaglandin E1 and thromboxane B2. 1984 Prostaglandins Leukot Med pmid:6588393
Branski D et al. Effect of cimetidine on human gastric and duodenal prostanoid synthesis. 1984 Scand. J. Gastroenterol. pmid:6589742
Oglesby TD and Gorman RR The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. 1984 Biochim. Biophys. Acta pmid:6424715
Grignani G et al. Activation of platelet prostaglandin biosynthesis pathway during neoplastic cell-induced platelet aggregation. 1984 Thromb. Res. pmid:6729776